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Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation.

Misra SR, Shankar YU, Rastogi V, Maragathavalli G - Contemp Clin Dent (2015)

Bottom Line: Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement.Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge.A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Medicine and Radiology, Institute of Dental Sciences, Bhubaneswar, Odisha, India.

ABSTRACT
Malignancy is characterized by anaplasia, invasiveness, and metastasis. Primary oral squamous cell carcinoma is the most prevalent oral malignancy, but secondary malignancy from distant sites have also been reported. Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement. Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge. Hence, in the differential diagnosis of malignant tumors of the oral cavity, it is essential to consider the occurrence of both primary as well as metastatic tumors despite the low incidence of the latter. A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis.

No MeSH data available.


Related in: MedlinePlus

Panoramic radiograph showing a localized, ill-defined mixed radiolucent-radiopaque lesion in the left body of the mandible
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Related In: Results  -  Collection

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Figure 3: Panoramic radiograph showing a localized, ill-defined mixed radiolucent-radiopaque lesion in the left body of the mandible

Mentions: Panoramic radiograph revealed ill-defined mixed radiopaque-radiolucent lesion with irregular bone destruction in 33–35 region. Hyperostosis was seen in the periapical region of 36, 37 which appeared to be separated from the surrounding bone [Figure 3].


Metastatic hepatocellular carcinoma in the maxilla and mandible, an extremely rare presentation.

Misra SR, Shankar YU, Rastogi V, Maragathavalli G - Contemp Clin Dent (2015)

Panoramic radiograph showing a localized, ill-defined mixed radiolucent-radiopaque lesion in the left body of the mandible
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4374307&req=5

Figure 3: Panoramic radiograph showing a localized, ill-defined mixed radiolucent-radiopaque lesion in the left body of the mandible
Mentions: Panoramic radiograph revealed ill-defined mixed radiopaque-radiolucent lesion with irregular bone destruction in 33–35 region. Hyperostosis was seen in the periapical region of 36, 37 which appeared to be separated from the surrounding bone [Figure 3].

Bottom Line: Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement.Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge.A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Medicine and Radiology, Institute of Dental Sciences, Bhubaneswar, Odisha, India.

ABSTRACT
Malignancy is characterized by anaplasia, invasiveness, and metastasis. Primary oral squamous cell carcinoma is the most prevalent oral malignancy, but secondary malignancy from distant sites have also been reported. Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement. Such secondary neoplasms do not have any pathognomonic clinical or radiologic findings, and therefore they pose a diagnostic challenge. Hence, in the differential diagnosis of malignant tumors of the oral cavity, it is essential to consider the occurrence of both primary as well as metastatic tumors despite the low incidence of the latter. A rare case of HCC metastasizing to both the maxilla and mandible is presented, in which the patient succumbed to the disease as a result of the delay in diagnosis.

No MeSH data available.


Related in: MedlinePlus