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Editorial: Innovative steps toward understanding sinonasal disease, improving diagnostics and optimizing patient care.

Carr TF - Am J Rhinol Allergy (2014 Sep-Oct)

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The September issue of the American Journal of Rhinology and Allergy includes a variety of original research publications and review articles which serve to expand our knowledge of disease and physiology, identify novel concepts in disease diagnosis and management, and encourage us to welcome a multidisciplinary approach to patient care... Subsequent symptom and endoscopic scoring showed that HSI had no impact upon postoperative outcomes... Although HSI significantly decreased IL-17a cytokine levels in the mucus at 1 and 3 months postoperatively, this effect was not seen for TNF-alpha, IL-6, or IL-10... Asthma was diagnosed in 26 patients (65%), a new diagnosis for a quarter of the patients... Atopy was not significantly associated with CRSwNP or asthma... Finally, in a novel study, Deniz and colleagues quantified mucociliary dysfunction, as measured by saccharin test, in patients with varying degrees of obstructive sleep apnea syndrome... They found that severe obstructive sleep apnea patients had significant deterioration in nasal mucociliary dysfunction when compared with control patients, putting this group at risk for sinonasal infection... Many patients experienced ocular or pulmonary symptoms, especially in patients with more severe symptoms... House dust mites were found to be the most significant allergens among these patients... Multiple articles in this issue focus on advancing clinical knowledge of sinonasal structures... A review article of respiratory epithelial adenomatoid hamartoma (REAH) features and treatment outcomes by Nguyen et al reports that REAH is a relatively common finding in nasal polyposis, may contribute to olfactory dysfunction, and endoscopic resection of this tissue can improve nasal obstruction and sense of smell... ElBadawey et al sought to assess the impact of three frontal sinus procedures – balloon sinuplasty, frontal recess clearance, or endoscopic modified Lothrop procedure – on quality of life as measured by the Glasgow Benefit inventory and SNOT22 questionnaires... This group found significant symptom and quality of life benefit from all three frontal sinus procedures... They found that adding DW-MRI increased sensitivity, specificity, negative and positive predictive values for differentiating between benign and malignant processes, encouraging the use of this modality in workup of sinonasal tumors.

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Tara F. Carr, M.D.
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Editorial: Innovative steps toward understanding sinonasal disease, improving diagnostics and optimizing patient care.

Carr TF - Am J Rhinol Allergy (2014 Sep-Oct)

Tara F. Carr, M.D.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4374133&req=5

FU1: Tara F. Carr, M.D.

View Article: PubMed Central - PubMed

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

The September issue of the American Journal of Rhinology and Allergy includes a variety of original research publications and review articles which serve to expand our knowledge of disease and physiology, identify novel concepts in disease diagnosis and management, and encourage us to welcome a multidisciplinary approach to patient care... Subsequent symptom and endoscopic scoring showed that HSI had no impact upon postoperative outcomes... Although HSI significantly decreased IL-17a cytokine levels in the mucus at 1 and 3 months postoperatively, this effect was not seen for TNF-alpha, IL-6, or IL-10... Asthma was diagnosed in 26 patients (65%), a new diagnosis for a quarter of the patients... Atopy was not significantly associated with CRSwNP or asthma... Finally, in a novel study, Deniz and colleagues quantified mucociliary dysfunction, as measured by saccharin test, in patients with varying degrees of obstructive sleep apnea syndrome... They found that severe obstructive sleep apnea patients had significant deterioration in nasal mucociliary dysfunction when compared with control patients, putting this group at risk for sinonasal infection... Many patients experienced ocular or pulmonary symptoms, especially in patients with more severe symptoms... House dust mites were found to be the most significant allergens among these patients... Multiple articles in this issue focus on advancing clinical knowledge of sinonasal structures... A review article of respiratory epithelial adenomatoid hamartoma (REAH) features and treatment outcomes by Nguyen et al reports that REAH is a relatively common finding in nasal polyposis, may contribute to olfactory dysfunction, and endoscopic resection of this tissue can improve nasal obstruction and sense of smell... ElBadawey et al sought to assess the impact of three frontal sinus procedures – balloon sinuplasty, frontal recess clearance, or endoscopic modified Lothrop procedure – on quality of life as measured by the Glasgow Benefit inventory and SNOT22 questionnaires... This group found significant symptom and quality of life benefit from all three frontal sinus procedures... They found that adding DW-MRI increased sensitivity, specificity, negative and positive predictive values for differentiating between benign and malignant processes, encouraging the use of this modality in workup of sinonasal tumors.

Show MeSH