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Cystic multiglandular maternal hyperparathyroidism diagnosed by neonatal hypocalcemic seizures.

Long K, Cartwright T, Sloan D, Lee C - J Surg Case Rep (2015)

Bottom Line: Concomitant evaluation of the mother revealed both elevated ionized calcium (5.9 mg/dl) and PTH (116 pg/ml).The infant was stabilized and discharged home.After increasing calcium supplementation appropriately, he was monitored with weekly office visits.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of General Surgery, University of Kentucky, Lexington, KY, USA Divsion of Endocrine Surgery, University of Kentucky, Lexington, KY, USA kristin.long@uky.edu.

No MeSH data available.


Related in: MedlinePlus

(a) Intraoperative photograph showing cystic parathyroid glands. (b) Cystic parathyroid glands.
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RJV031F1: (a) Intraoperative photograph showing cystic parathyroid glands. (b) Cystic parathyroid glands.

Mentions: The patient was diagnosed with primary hyperparathyroidism likely due to multiglandular disease and was prepared for parathyroidectomy. After an extensive exploration, three significantly enlarged cystic glands were identified and removed (Fig. 1). Intraoperative PTH levels dropped appropriately after parathyroidectomy, thyroid lobectomy and cervical thymectomy from a baseline of 104 pg/ml to a final value of 41.1 pg/ml. Pathology noted three hypercellular, cystic parathyroid glands with mucoid degeneration weighing 6.200, 1.846 and 0.110 g as well as a separate 3 mm focus of hypercellular parathyroid tissue in the pretracheal tissue. The calcium the morning after surgery was normal at 8.7 mg/dl.Figure 1:


Cystic multiglandular maternal hyperparathyroidism diagnosed by neonatal hypocalcemic seizures.

Long K, Cartwright T, Sloan D, Lee C - J Surg Case Rep (2015)

(a) Intraoperative photograph showing cystic parathyroid glands. (b) Cystic parathyroid glands.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4374092&req=5

RJV031F1: (a) Intraoperative photograph showing cystic parathyroid glands. (b) Cystic parathyroid glands.
Mentions: The patient was diagnosed with primary hyperparathyroidism likely due to multiglandular disease and was prepared for parathyroidectomy. After an extensive exploration, three significantly enlarged cystic glands were identified and removed (Fig. 1). Intraoperative PTH levels dropped appropriately after parathyroidectomy, thyroid lobectomy and cervical thymectomy from a baseline of 104 pg/ml to a final value of 41.1 pg/ml. Pathology noted three hypercellular, cystic parathyroid glands with mucoid degeneration weighing 6.200, 1.846 and 0.110 g as well as a separate 3 mm focus of hypercellular parathyroid tissue in the pretracheal tissue. The calcium the morning after surgery was normal at 8.7 mg/dl.Figure 1:

Bottom Line: Concomitant evaluation of the mother revealed both elevated ionized calcium (5.9 mg/dl) and PTH (116 pg/ml).The infant was stabilized and discharged home.After increasing calcium supplementation appropriately, he was monitored with weekly office visits.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of General Surgery, University of Kentucky, Lexington, KY, USA Divsion of Endocrine Surgery, University of Kentucky, Lexington, KY, USA kristin.long@uky.edu.

No MeSH data available.


Related in: MedlinePlus