Cardiac telocytes: serial dynamic images in cell culture.
Bottom Line: We used a protocol that favoured interstitial cell selection from adult mouse myocardium.Videomicroscopy showed dynamic interactions of neighbour TC during the network formation.During their movement, TC leave behind distal segments (podomeres) of their Tp as guiding marks for the neighbouring cells to follow during network rearrangement.
Affiliation: Department of Cellular and Molecular Medicine, 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania.Show MeSH
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Mentions: Figure 1 shows that some cells in the 48-hr-old culture, which correspond to the TC morphological profile, extend very long and thin Tp that reach out and temporarily interconnect with similar cells in a primary network-like layout. Cell culture confirms repetitive Tp structure shown in electron microscopy (EM) studies , of alternating thin segments (podomeres) and dilations (podoms). The mobility, as well as the plasticity of Tp, is based on this moniliform ‘design’.
Affiliation: Department of Cellular and Molecular Medicine, 'Carol Davila' University of Medicine and Pharmacy, Bucharest, Romania.