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Identification of telocytes in skeletal muscle interstitium: implication for muscle regeneration.

Popescu LM, Manole E, Serboiu CS, Manole CG, Suciu LC, Gherghiceanu M, Popescu BO - J. Cell. Mol. Med. (2011)

Bottom Line: The same phenotypic profile was demonstrated in cell cultures.We also described non-satellite (resident) progenitor cell niche.In culture, TCs (but not satellite cells) emerge from muscle explants and form networks suggesting a key role in muscle regeneration and repair, at least after trauma.

View Article: PubMed Central - PubMed

Affiliation: Department of Cellular and Molecular Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. LMP@jcmm.org

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Mouse skeletal muscle in cell culture. The same cell was analysed by (A) phase contrast microscopy and (B) fluorescence microscopy after labelling the mitochondria of living cells with MitoTracker Green FM. Mitochondria are concentrated around the cell nucleus and within the podoms (arrows). Photographic reconstruction; original magnification: 1000×.
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fig12: Mouse skeletal muscle in cell culture. The same cell was analysed by (A) phase contrast microscopy and (B) fluorescence microscopy after labelling the mitochondria of living cells with MitoTracker Green FM. Mitochondria are concentrated around the cell nucleus and within the podoms (arrows). Photographic reconstruction; original magnification: 1000×.

Mentions: The dilations along Tps, called podoms, accommodate many mitochondria as shown by fluorescent labelling of living cells with the lipophylic, selective dye MitoTracker Green FM, which is concentrated by active mitochondria (Fig. 12).


Identification of telocytes in skeletal muscle interstitium: implication for muscle regeneration.

Popescu LM, Manole E, Serboiu CS, Manole CG, Suciu LC, Gherghiceanu M, Popescu BO - J. Cell. Mol. Med. (2011)

Mouse skeletal muscle in cell culture. The same cell was analysed by (A) phase contrast microscopy and (B) fluorescence microscopy after labelling the mitochondria of living cells with MitoTracker Green FM. Mitochondria are concentrated around the cell nucleus and within the podoms (arrows). Photographic reconstruction; original magnification: 1000×.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4373336&req=5

fig12: Mouse skeletal muscle in cell culture. The same cell was analysed by (A) phase contrast microscopy and (B) fluorescence microscopy after labelling the mitochondria of living cells with MitoTracker Green FM. Mitochondria are concentrated around the cell nucleus and within the podoms (arrows). Photographic reconstruction; original magnification: 1000×.
Mentions: The dilations along Tps, called podoms, accommodate many mitochondria as shown by fluorescent labelling of living cells with the lipophylic, selective dye MitoTracker Green FM, which is concentrated by active mitochondria (Fig. 12).

Bottom Line: The same phenotypic profile was demonstrated in cell cultures.We also described non-satellite (resident) progenitor cell niche.In culture, TCs (but not satellite cells) emerge from muscle explants and form networks suggesting a key role in muscle regeneration and repair, at least after trauma.

View Article: PubMed Central - PubMed

Affiliation: Department of Cellular and Molecular Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. LMP@jcmm.org

Show MeSH
Related in: MedlinePlus