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Patient-reported outcome measures for asthma: a systematic review.

Worth A, Hammersley V, Knibb R, Flokstra-de-Blok B, DunnGalvin A, Walker S, Dubois AE, Sheikh A - NPJ Prim Care Respir Med (2014)

Bottom Line: Patient-reported outcome measures (PROMs) are measures of the outcome of treatment(s) reported directly by the patient or carer.We identified 28 generic PROMs commonly used in conjunction with asthma-specific instruments.In particular, there is a need to ensure these are validated for use in clinical settings, acceptable to patients, caregivers and clinicians, and yield meaningful outcomes.

View Article: PubMed Central - PubMed

Affiliation: Allergy & Respiratory Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK.

ABSTRACT

Background: Patient-reported outcome measures (PROMs) are measures of the outcome of treatment(s) reported directly by the patient or carer. There is increasing international policy interest in using these to assess the impact of clinical care.

Aims: To identify suitably validated PROMs for asthma and examine their potential for use in clinical settings.

Methods: We systematically searched MEDLINE, EMBASE and Web of Science databases from 1990 onwards to identify PROMs for asthma. These were critically appraised, then narratively synthesised. We also identified the generic PROMs commonly used alongside asthma-specific PROMs.

Results: We identified 68 PROMs for asthma, 13 of which were selected through screening as being adequately developed to warrant full-quality appraisal: 8 for adults, 4 for children and 1 for a child's caregiver. The PROMs found to be sufficiently well validated to offer promise for use in clinical settings were the Asthma Quality of Life Questionnaire (AQLQ) and mini-AQLQ for adults, and Pediatric Asthma Quality of Life Questionnaire for children. Rhinasthma was considered promising in simultaneously assessing the impact of asthma and rhinitis in those with coexistent disease. We identified 28 generic PROMs commonly used in conjunction with asthma-specific instruments.

Conclusions: We identified asthma PROMs that offer the greatest potential for use in clinical settings. Further work is needed to assess whether these are fit-for-purpose for use in clinical practice with individual patients. In particular, there is a need to ensure these are validated for use in clinical settings, acceptable to patients, caregivers and clinicians, and yield meaningful outcomes.

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Related in: MedlinePlus

Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow diagram. PROM, patient-reported outcome measure.
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fig1: Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow diagram. PROM, patient-reported outcome measure.

Mentions: Our searches identified 6,316 papers, from which we identified 593 papers on PROMs’ developmental work. Among these, we identified 68 PROMs for asthma; 13 were selected through screening as being sufficiently well developed and validated to merit full-quality appraisal: 8 for adults, 4 for children and 1 for a child’s caregiver (see Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow diagram, Figure 1).


Patient-reported outcome measures for asthma: a systematic review.

Worth A, Hammersley V, Knibb R, Flokstra-de-Blok B, DunnGalvin A, Walker S, Dubois AE, Sheikh A - NPJ Prim Care Respir Med (2014)

Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow diagram. PROM, patient-reported outcome measure.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4373322&req=5

fig1: Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow diagram. PROM, patient-reported outcome measure.
Mentions: Our searches identified 6,316 papers, from which we identified 593 papers on PROMs’ developmental work. Among these, we identified 68 PROMs for asthma; 13 were selected through screening as being sufficiently well developed and validated to merit full-quality appraisal: 8 for adults, 4 for children and 1 for a child’s caregiver (see Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow diagram, Figure 1).

Bottom Line: Patient-reported outcome measures (PROMs) are measures of the outcome of treatment(s) reported directly by the patient or carer.We identified 28 generic PROMs commonly used in conjunction with asthma-specific instruments.In particular, there is a need to ensure these are validated for use in clinical settings, acceptable to patients, caregivers and clinicians, and yield meaningful outcomes.

View Article: PubMed Central - PubMed

Affiliation: Allergy & Respiratory Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK.

ABSTRACT

Background: Patient-reported outcome measures (PROMs) are measures of the outcome of treatment(s) reported directly by the patient or carer. There is increasing international policy interest in using these to assess the impact of clinical care.

Aims: To identify suitably validated PROMs for asthma and examine their potential for use in clinical settings.

Methods: We systematically searched MEDLINE, EMBASE and Web of Science databases from 1990 onwards to identify PROMs for asthma. These were critically appraised, then narratively synthesised. We also identified the generic PROMs commonly used alongside asthma-specific PROMs.

Results: We identified 68 PROMs for asthma, 13 of which were selected through screening as being adequately developed to warrant full-quality appraisal: 8 for adults, 4 for children and 1 for a child's caregiver. The PROMs found to be sufficiently well validated to offer promise for use in clinical settings were the Asthma Quality of Life Questionnaire (AQLQ) and mini-AQLQ for adults, and Pediatric Asthma Quality of Life Questionnaire for children. Rhinasthma was considered promising in simultaneously assessing the impact of asthma and rhinitis in those with coexistent disease. We identified 28 generic PROMs commonly used in conjunction with asthma-specific instruments.

Conclusions: We identified asthma PROMs that offer the greatest potential for use in clinical settings. Further work is needed to assess whether these are fit-for-purpose for use in clinical practice with individual patients. In particular, there is a need to ensure these are validated for use in clinical settings, acceptable to patients, caregivers and clinicians, and yield meaningful outcomes.

Show MeSH
Related in: MedlinePlus