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An Overlap of Angiolymphoid Hyperplasia with Eosinophilia and Kimura's Disease: Successful Treatment of Skin Lesions with Cryotherapy.

Reddy PK, Prasad AL, Sumathy TK, Shivaswamy KN, Ranganathan C - Indian J Dermatol (2015 Mar-Apr)

Bottom Line: A CT chest revealed left axillary lymphadenopathy.ALHE and KD are common in the head and neck region, but no reports of an overlap, presenting with lesions in the axillae are available to date, to the best of our knowledge.Response of skin lesions to cryotherapy is highlighted.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, M.S. Ramaiah Medical College and Teaching Hospital, Bangalore, Karnataka, India.

ABSTRACT
Kimura's disease is characterized by a triad of painless subcutaneous masses, eosinophilia in the peripheral blood and in tissues with marked increase in Serum Ig E. Angiolymphoid hyperplasia with eosinophilia (ALHE) manifests with the presence of dermal papules and nodules. Unique clinical, histopathological, and biochemical findings are noted in these individual entities. A 32-year-female presented with multiple nodules in the axillae for 2 years. Peripheral smear showed eosinophilia with AEC of 6080. Histopathological examination showed features of overlap. Antinuclear antibody immunoflorescence was was negative. CD31, CD34, and FVIII were positive in vascular component. A CT chest revealed left axillary lymphadenopathy. The patient was treated with Cryotherapy and there was complete regression of skin lesions, with no recurrence after 1 year of follow-up. ALHE and KD are common in the head and neck region, but no reports of an overlap, presenting with lesions in the axillae are available to date, to the best of our knowledge. Response of skin lesions to cryotherapy is highlighted.

No MeSH data available.


Related in: MedlinePlus

Complete regression of lesions following cryotherapy
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Figure 8: Complete regression of lesions following cryotherapy

Mentions: Skin lesions were treated with cryotherapy. Two to three freeze–thaw cycles with 10-s freezing and 2-min thawing per session were done at weekly intervals for 2 weeks. There was complete regression of skin lesions [Figures 7 and 8] with no recurrence after 1 year of follow-up. There were no episodes of Raynaud's phenomenon after 1 year of follow-up.


An Overlap of Angiolymphoid Hyperplasia with Eosinophilia and Kimura's Disease: Successful Treatment of Skin Lesions with Cryotherapy.

Reddy PK, Prasad AL, Sumathy TK, Shivaswamy KN, Ranganathan C - Indian J Dermatol (2015 Mar-Apr)

Complete regression of lesions following cryotherapy
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4372959&req=5

Figure 8: Complete regression of lesions following cryotherapy
Mentions: Skin lesions were treated with cryotherapy. Two to three freeze–thaw cycles with 10-s freezing and 2-min thawing per session were done at weekly intervals for 2 weeks. There was complete regression of skin lesions [Figures 7 and 8] with no recurrence after 1 year of follow-up. There were no episodes of Raynaud's phenomenon after 1 year of follow-up.

Bottom Line: A CT chest revealed left axillary lymphadenopathy.ALHE and KD are common in the head and neck region, but no reports of an overlap, presenting with lesions in the axillae are available to date, to the best of our knowledge.Response of skin lesions to cryotherapy is highlighted.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, M.S. Ramaiah Medical College and Teaching Hospital, Bangalore, Karnataka, India.

ABSTRACT
Kimura's disease is characterized by a triad of painless subcutaneous masses, eosinophilia in the peripheral blood and in tissues with marked increase in Serum Ig E. Angiolymphoid hyperplasia with eosinophilia (ALHE) manifests with the presence of dermal papules and nodules. Unique clinical, histopathological, and biochemical findings are noted in these individual entities. A 32-year-female presented with multiple nodules in the axillae for 2 years. Peripheral smear showed eosinophilia with AEC of 6080. Histopathological examination showed features of overlap. Antinuclear antibody immunoflorescence was was negative. CD31, CD34, and FVIII were positive in vascular component. A CT chest revealed left axillary lymphadenopathy. The patient was treated with Cryotherapy and there was complete regression of skin lesions, with no recurrence after 1 year of follow-up. ALHE and KD are common in the head and neck region, but no reports of an overlap, presenting with lesions in the axillae are available to date, to the best of our knowledge. Response of skin lesions to cryotherapy is highlighted.

No MeSH data available.


Related in: MedlinePlus