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Multiple painless cutaneous nodules.

Khodaee M, Amir M, Spittler J, Abdollahi M - Indian J Dermatol (2015 Mar-Apr)

View Article: PubMed Central - PubMed

Affiliation: Department of Family Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA.

AUTOMATICALLY GENERATED EXCERPT
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A 34-year-old gentleman presents with three asymptomatic skin nodules on his lower abdomen, right flank, and lower back that have been enlarging for 4 months... He denies any weight change, fatigue, or other symptoms... Past medical history is significant for a “similar” lesion on his buttock which was removed and diagnosed as a trichilemmal (pilar) cyst 4 years ago... Histological examination of the right flank tumor revealed a trichilemmal cyst... Only IADVL members residing in India are allowed to take part in IJD® QUIZ... The editors, editorial board members, advisors and employees of the journal and members of their immediate family are not eligible to take part in IJD® QUIZ... Persons other than Indian nationals, or Indian nationals living out of India are ineligible to enter the IJD® QUIZ... This round will be closed on March 31, 2015... The results will be declared online on April 1, 2015... Shraddha Uprety, PGIMER, Chandigarh Resham Vasani, Anand Polyclinic, Matunga, Mumbai Jimish Bagadia, K.J.Somaiya hospital, Mumbai Sarina Jain, Ankan Gupta, Sumit Gupta, Anuj Tenani, Sahil Mrigpuri, Ishad Aggarwal, Gitesh Sawatkar, Sonal Tibrewal, Anup Kumar Tiwary, Anuradha, Pallavi Jha, Prameela Talakola, Poonam Puri, Sonali Bhat, Swetha Jain, Akhilesh Behra, Manisha thapa, Sourabh Jain, Tirthankar Gayen, Rakesh Kumar Patel, Jaydip Tank, Shruti Alhad Jadhav, Koyani Pooja, Anisha Sethi, Surajit Gorai, Samkit Shah, Vishal Chugh, Somodyuti Chandra, Sumit Sethi, Anirban Das, Riti Bhatia, Vishal Gupta, Katrodiya Nilesh, Ashish Jagati, Mugdha Jhamwar, Sanjay Bosamiya, Anupama, Suneil Pravin Gandhi, Geeti Khullar, Angoori Gnaneshwar Rao, Shamma Aboobacker, Keerthi Subramaniam, Sudhir Nayak U.K., M.Pavan Kumar, C.Vijay Krishna, Shiti Bose, Priyanka Jain, Suman Patra, Pooja Agarwal, Jasveen Kaur, Anuradha Kakkanatt Babu, Kusuma M R, Vinitha Gopalakrishnan, S... Chidambara Murthy, Khushboo Gupta, Alice Eleanor, Y, V... Ramesh

No MeSH data available.


Immunohistochemistry depicting diffuse and strong positive nuclear and cytoplasmic response with S100 protein (original magnification ×4)
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Figure 4: Immunohistochemistry depicting diffuse and strong positive nuclear and cytoplasmic response with S100 protein (original magnification ×4)

Mentions: Histological examination of the right flank tumor revealed a trichilemmal cyst. The hematoxylin-eosin-stained sections of the tumor on the lower abdomen [Figure 1] showed a non-encapsulated dermal tumor composed of irregularly arranged sheets of large polyhedral cells with small central hyperchromatic nuclei and abundant granular eosinophilic cytoplasm [Figure 3]. There was no evidence of necrosis, cytologic atypia, or mitotic figures. The overlying epidermis was relatively unremarkable with an intact basal layer, granular layer, and stratum corneum. Pseudoepitheliomatous hyperplasia was not seen. The tumor cells showed diffuse, strong nuclear and cytoplasmic staining with S100 protein [Figure 4] and strong cytoplasmic staining with CD68 [Figure 5]. The periodic acid-Schiff (PAS) stain was not performed.


Multiple painless cutaneous nodules.

Khodaee M, Amir M, Spittler J, Abdollahi M - Indian J Dermatol (2015 Mar-Apr)

Immunohistochemistry depicting diffuse and strong positive nuclear and cytoplasmic response with S100 protein (original magnification ×4)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4372925&req=5

Figure 4: Immunohistochemistry depicting diffuse and strong positive nuclear and cytoplasmic response with S100 protein (original magnification ×4)
Mentions: Histological examination of the right flank tumor revealed a trichilemmal cyst. The hematoxylin-eosin-stained sections of the tumor on the lower abdomen [Figure 1] showed a non-encapsulated dermal tumor composed of irregularly arranged sheets of large polyhedral cells with small central hyperchromatic nuclei and abundant granular eosinophilic cytoplasm [Figure 3]. There was no evidence of necrosis, cytologic atypia, or mitotic figures. The overlying epidermis was relatively unremarkable with an intact basal layer, granular layer, and stratum corneum. Pseudoepitheliomatous hyperplasia was not seen. The tumor cells showed diffuse, strong nuclear and cytoplasmic staining with S100 protein [Figure 4] and strong cytoplasmic staining with CD68 [Figure 5]. The periodic acid-Schiff (PAS) stain was not performed.

View Article: PubMed Central - PubMed

Affiliation: Department of Family Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA.

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

A 34-year-old gentleman presents with three asymptomatic skin nodules on his lower abdomen, right flank, and lower back that have been enlarging for 4 months... He denies any weight change, fatigue, or other symptoms... Past medical history is significant for a “similar” lesion on his buttock which was removed and diagnosed as a trichilemmal (pilar) cyst 4 years ago... Histological examination of the right flank tumor revealed a trichilemmal cyst... Only IADVL members residing in India are allowed to take part in IJD® QUIZ... The editors, editorial board members, advisors and employees of the journal and members of their immediate family are not eligible to take part in IJD® QUIZ... Persons other than Indian nationals, or Indian nationals living out of India are ineligible to enter the IJD® QUIZ... This round will be closed on March 31, 2015... The results will be declared online on April 1, 2015... Shraddha Uprety, PGIMER, Chandigarh Resham Vasani, Anand Polyclinic, Matunga, Mumbai Jimish Bagadia, K.J.Somaiya hospital, Mumbai Sarina Jain, Ankan Gupta, Sumit Gupta, Anuj Tenani, Sahil Mrigpuri, Ishad Aggarwal, Gitesh Sawatkar, Sonal Tibrewal, Anup Kumar Tiwary, Anuradha, Pallavi Jha, Prameela Talakola, Poonam Puri, Sonali Bhat, Swetha Jain, Akhilesh Behra, Manisha thapa, Sourabh Jain, Tirthankar Gayen, Rakesh Kumar Patel, Jaydip Tank, Shruti Alhad Jadhav, Koyani Pooja, Anisha Sethi, Surajit Gorai, Samkit Shah, Vishal Chugh, Somodyuti Chandra, Sumit Sethi, Anirban Das, Riti Bhatia, Vishal Gupta, Katrodiya Nilesh, Ashish Jagati, Mugdha Jhamwar, Sanjay Bosamiya, Anupama, Suneil Pravin Gandhi, Geeti Khullar, Angoori Gnaneshwar Rao, Shamma Aboobacker, Keerthi Subramaniam, Sudhir Nayak U.K., M.Pavan Kumar, C.Vijay Krishna, Shiti Bose, Priyanka Jain, Suman Patra, Pooja Agarwal, Jasveen Kaur, Anuradha Kakkanatt Babu, Kusuma M R, Vinitha Gopalakrishnan, S... Chidambara Murthy, Khushboo Gupta, Alice Eleanor, Y, V... Ramesh

No MeSH data available.