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Secondary Syphilid Developing Over Healed Lesions of Varicella: Wolf's Isotopic Response?

Gayen T, Shome K, Bandyopadhyay D, Roy S, Gharami RC - Indian J Dermatol (2015 Mar-Apr)

Bottom Line: Isotopic response is a distinctive phenomenon in which a new skin disorder occurs at the site of another, unrelated, and already healed skin disease.Most of the cases documented in the literature were associated with herpes zoster as primary disease while the list of "second" diseases is quite long.We report here a hitherto unreported occurrence of isotopic response in which secondary syphilis occurred on the healed lesions of varicella.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Medical College and Hospital, Kolkata, West Bengal, India.

ABSTRACT
Isotopic response is a distinctive phenomenon in which a new skin disorder occurs at the site of another, unrelated, and already healed skin disease. Most of the cases documented in the literature were associated with herpes zoster as primary disease while the list of "second" diseases is quite long. We report here a hitherto unreported occurrence of isotopic response in which secondary syphilis occurred on the healed lesions of varicella.

No MeSH data available.


Related in: MedlinePlus

Intense upper dermal infiltrate composed primarily of plasma cells (H and E, ×100)
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Figure 4: Intense upper dermal infiltrate composed primarily of plasma cells (H and E, ×100)

Mentions: On histopathology, there was hyperkeratosis with parakeratosis and acanthosis. There was dermal edema, profuse pandermal infiltration of chronic inflammatory cells, chiefly plasma cells and lymphocytes [Figure 4]. She was given injection benzathine penicillin (2.4 million units) intramuscularly, which resulted in rapid clinical improvement within a few days.


Secondary Syphilid Developing Over Healed Lesions of Varicella: Wolf's Isotopic Response?

Gayen T, Shome K, Bandyopadhyay D, Roy S, Gharami RC - Indian J Dermatol (2015 Mar-Apr)

Intense upper dermal infiltrate composed primarily of plasma cells (H and E, ×100)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4372916&req=5

Figure 4: Intense upper dermal infiltrate composed primarily of plasma cells (H and E, ×100)
Mentions: On histopathology, there was hyperkeratosis with parakeratosis and acanthosis. There was dermal edema, profuse pandermal infiltration of chronic inflammatory cells, chiefly plasma cells and lymphocytes [Figure 4]. She was given injection benzathine penicillin (2.4 million units) intramuscularly, which resulted in rapid clinical improvement within a few days.

Bottom Line: Isotopic response is a distinctive phenomenon in which a new skin disorder occurs at the site of another, unrelated, and already healed skin disease.Most of the cases documented in the literature were associated with herpes zoster as primary disease while the list of "second" diseases is quite long.We report here a hitherto unreported occurrence of isotopic response in which secondary syphilis occurred on the healed lesions of varicella.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Medical College and Hospital, Kolkata, West Bengal, India.

ABSTRACT
Isotopic response is a distinctive phenomenon in which a new skin disorder occurs at the site of another, unrelated, and already healed skin disease. Most of the cases documented in the literature were associated with herpes zoster as primary disease while the list of "second" diseases is quite long. We report here a hitherto unreported occurrence of isotopic response in which secondary syphilis occurred on the healed lesions of varicella.

No MeSH data available.


Related in: MedlinePlus