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Riedel's Thyroiditis with Intense FDG Uptake Demonstrated on FDG PET/CT.

Mansberg R, Bency R, Shen L, Bui C, Park K - Mol Imaging Radionucl Ther (2015)

Bottom Line: Clinical examination revealed diffusely enlarged, firm, non-tender thyroid gland.The goitre reduced in size with thyroid hormone replacement and steroids, however the patient was lost to follow up.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: Nepean Hospital, Clinic of PET and Nuclear Medicine, Penrith, Australia. E-mail: mansberg@usyd.edu.au.

ABSTRACT
A 39 year old female presented with rapidly enlarging goitre, minimal obstructive symptoms and no constitutional symptoms. Clinical examination revealed diffusely enlarged, firm, non-tender thyroid gland. Biochemical investigations showed subclinical hypothyroidism, positive thyroid antibodies and unremarkable inflammatory markers. Ultrasound examination and CT scan of the neck were suspicious of Riedels thyroiditis. The patient was referred for a FDG PET scan to evaluate for systemic fibro-inflammatory process or lymphoma. Subsequent core biopsy of the thyroid gland demonstrated a chronic inflammatory process with fibrosis consistent with Riedels thyroiditis. A FDG PET/CT study showed diffuse FDG uptake in the thyroid gland and no abnormal retroperitoneal FDG uptake elsewhere to suggest active retroperitoneal fibrosis. The goitre reduced in size with thyroid hormone replacement and steroids, however the patient was lost to follow up.

No MeSH data available.


Related in: MedlinePlus

Axial image from neck CT demonstrated asymmetrically enlarged thyroid gland (right left) with lobulated appearance and mild compression of the right side of the trachea (Solid white arrow).
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f2: Axial image from neck CT demonstrated asymmetrically enlarged thyroid gland (right left) with lobulated appearance and mild compression of the right side of the trachea (Solid white arrow).

Mentions: Thyroid ultrasound demonstrated diffusely hypo echoic, asymmetrically enlarged thyroid gland (right>left) with diffusely increased vascularity, but with no discrete focal mass lesions. Figure 1 (only right thyroid lobe shown): Contrast enhanced diagnostic CT of the Neck, chest, abdomen and pelvis was performed. Axial image from neck CT demonstrated asymmetrically enlarged thyroid gland (right>left) with lobulated appearance and mild compression of the right side of the trachea (Solid white arrow) (Figure 2). There was no evidence of direct involvement of surrounding structures in the neck or of retroperitoneal fibrosis.


Riedel's Thyroiditis with Intense FDG Uptake Demonstrated on FDG PET/CT.

Mansberg R, Bency R, Shen L, Bui C, Park K - Mol Imaging Radionucl Ther (2015)

Axial image from neck CT demonstrated asymmetrically enlarged thyroid gland (right left) with lobulated appearance and mild compression of the right side of the trachea (Solid white arrow).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4372770&req=5

f2: Axial image from neck CT demonstrated asymmetrically enlarged thyroid gland (right left) with lobulated appearance and mild compression of the right side of the trachea (Solid white arrow).
Mentions: Thyroid ultrasound demonstrated diffusely hypo echoic, asymmetrically enlarged thyroid gland (right>left) with diffusely increased vascularity, but with no discrete focal mass lesions. Figure 1 (only right thyroid lobe shown): Contrast enhanced diagnostic CT of the Neck, chest, abdomen and pelvis was performed. Axial image from neck CT demonstrated asymmetrically enlarged thyroid gland (right>left) with lobulated appearance and mild compression of the right side of the trachea (Solid white arrow) (Figure 2). There was no evidence of direct involvement of surrounding structures in the neck or of retroperitoneal fibrosis.

Bottom Line: Clinical examination revealed diffusely enlarged, firm, non-tender thyroid gland.The goitre reduced in size with thyroid hormone replacement and steroids, however the patient was lost to follow up.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: Nepean Hospital, Clinic of PET and Nuclear Medicine, Penrith, Australia. E-mail: mansberg@usyd.edu.au.

ABSTRACT
A 39 year old female presented with rapidly enlarging goitre, minimal obstructive symptoms and no constitutional symptoms. Clinical examination revealed diffusely enlarged, firm, non-tender thyroid gland. Biochemical investigations showed subclinical hypothyroidism, positive thyroid antibodies and unremarkable inflammatory markers. Ultrasound examination and CT scan of the neck were suspicious of Riedels thyroiditis. The patient was referred for a FDG PET scan to evaluate for systemic fibro-inflammatory process or lymphoma. Subsequent core biopsy of the thyroid gland demonstrated a chronic inflammatory process with fibrosis consistent with Riedels thyroiditis. A FDG PET/CT study showed diffuse FDG uptake in the thyroid gland and no abnormal retroperitoneal FDG uptake elsewhere to suggest active retroperitoneal fibrosis. The goitre reduced in size with thyroid hormone replacement and steroids, however the patient was lost to follow up.

No MeSH data available.


Related in: MedlinePlus