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A microfluidic device based on an evaporation-driven micropump.

Nie C, Frijns AJ, Mandamparambil R, den Toonder JM - Biomed Microdevices (2015)

Bottom Line: Typical results show that with 1 to 61 pores (diameter = 250 μm, pitch = 500 μm) flow rates of 7.3 × 10(-3) to 1.2 × 10(-1) μL/min are achieved.The results are theoretically analyzed using an evaporation model that includes an evaporation correction factor.The theoretical and experimental results are in good agreement.

View Article: PubMed Central - PubMed

Affiliation: Department of Mechanical Engineering, Eindhoven University of Technology, P.O. Box 513, 5600 MB, Eindhoven, The Netherlands.

ABSTRACT
In this paper we introduce a microfluidic device ultimately to be applied as a wearable sweat sensor. We show proof-of-principle of the microfluidic functions of the device, namely fluid collection and continuous fluid flow pumping. A filter-paper based layer, that eventually will form the interface between the device and the skin, is used to collect the fluid (e.g., sweat) and enter this into the microfluidic device. A controllable evaporation driven pump is used to drive a continuous fluid flow through a microfluidic channel and over a sensing area. The key element of the pump is a micro-porous membrane mounted at the channel outlet, such that a pore array with a regular hexagonal arrangement is realized through which the fluid evaporates, which drives the flow within the channel. The system is completely fabricated on flexible polyethylene terephthalate (PET) foils, which can be the backbone material for flexible electronics applications, such that it is compatible with volume production approaches like Roll-to-Roll technology. The evaporation rate can be controlled by varying the outlet geometry and the temperature. The generated flows are analyzed experimentally using Particle Tracking Velocimetry (PTV). Typical results show that with 1 to 61 pores (diameter = 250 μm, pitch = 500 μm) flow rates of 7.3 × 10(-3) to 1.2 × 10(-1) μL/min are achieved. When the surface temperature is increased by 9.4°C, the flow rate is increased by 130 %. The results are theoretically analyzed using an evaporation model that includes an evaporation correction factor. The theoretical and experimental results are in good agreement.

No MeSH data available.


The geometrical channel parameters used for the 2D-PTV analysis
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Fig4: The geometrical channel parameters used for the 2D-PTV analysis

Mentions: The x-coordinate is along the channel length, in the flow direction. We choose the mid-point of the rectangular cross-section channel as the origin (y,z) = (0,0). The geometrical parameters b and c are half of the width and half of the height of the cross-section respectively (see Fig. 4).Fig. 4


A microfluidic device based on an evaporation-driven micropump.

Nie C, Frijns AJ, Mandamparambil R, den Toonder JM - Biomed Microdevices (2015)

The geometrical channel parameters used for the 2D-PTV analysis
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4372687&req=5

Fig4: The geometrical channel parameters used for the 2D-PTV analysis
Mentions: The x-coordinate is along the channel length, in the flow direction. We choose the mid-point of the rectangular cross-section channel as the origin (y,z) = (0,0). The geometrical parameters b and c are half of the width and half of the height of the cross-section respectively (see Fig. 4).Fig. 4

Bottom Line: Typical results show that with 1 to 61 pores (diameter = 250 μm, pitch = 500 μm) flow rates of 7.3 × 10(-3) to 1.2 × 10(-1) μL/min are achieved.The results are theoretically analyzed using an evaporation model that includes an evaporation correction factor.The theoretical and experimental results are in good agreement.

View Article: PubMed Central - PubMed

Affiliation: Department of Mechanical Engineering, Eindhoven University of Technology, P.O. Box 513, 5600 MB, Eindhoven, The Netherlands.

ABSTRACT
In this paper we introduce a microfluidic device ultimately to be applied as a wearable sweat sensor. We show proof-of-principle of the microfluidic functions of the device, namely fluid collection and continuous fluid flow pumping. A filter-paper based layer, that eventually will form the interface between the device and the skin, is used to collect the fluid (e.g., sweat) and enter this into the microfluidic device. A controllable evaporation driven pump is used to drive a continuous fluid flow through a microfluidic channel and over a sensing area. The key element of the pump is a micro-porous membrane mounted at the channel outlet, such that a pore array with a regular hexagonal arrangement is realized through which the fluid evaporates, which drives the flow within the channel. The system is completely fabricated on flexible polyethylene terephthalate (PET) foils, which can be the backbone material for flexible electronics applications, such that it is compatible with volume production approaches like Roll-to-Roll technology. The evaporation rate can be controlled by varying the outlet geometry and the temperature. The generated flows are analyzed experimentally using Particle Tracking Velocimetry (PTV). Typical results show that with 1 to 61 pores (diameter = 250 μm, pitch = 500 μm) flow rates of 7.3 × 10(-3) to 1.2 × 10(-1) μL/min are achieved. When the surface temperature is increased by 9.4°C, the flow rate is increased by 130 %. The results are theoretically analyzed using an evaporation model that includes an evaporation correction factor. The theoretical and experimental results are in good agreement.

No MeSH data available.