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A case report of ultrasound-guided interstitial brachytherapy for abdominal wall metastases of ovarian cancer.

Shi D, Wu N, Zhao H, He M, Han D, Cheng G - J Contemp Brachytherapy (2015)

Bottom Line: The patient is a 44-year-old female with a diagnosis of stage IA ovarian cancer.After surgery and two cycles of chemotherapy with paclitaxel and carboplatin, the patient noticed dull pain in the lower abdomen and found a mass located in the subcutaneous tissue, below the operative incision.A diagnostic biopsy showed abdominal wall metastases.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun, China ; These two authors contributed equally to this work.

ABSTRACT

Purpose: To report the treatment effect of interstitial brachytherapy for abdominal wall metastases of ovarian cancer.

Material and methods: The patient is a 44-year-old female with a diagnosis of stage IA ovarian cancer. After surgery and two cycles of chemotherapy with paclitaxel and carboplatin, the patient noticed dull pain in the lower abdomen and found a mass located in the subcutaneous tissue, below the operative incision. A diagnostic biopsy showed abdominal wall metastases. After external radiotherapy with a dose of 39.6 Gy in 22 fractions, the residual tumor was treated with interstitial brachytherapy under ultrasound guidance. The brachytherapy dose was 18 Gy in 6 fractions of 3 Gy each.

Results: After 3 weeks of brachytherapy, the tumor had disappeared completely. Interstitial brachytherapy was feasible.

Conclusions: Interstitial brachytherapy may be a proposed treatment strategy for inoperable superficial metastases, especially for low radiosensitivity cancer.

No MeSH data available.


Related in: MedlinePlus

The MR of abdominal wall (A, B) before, and (C, D) 3 weeks after brachytherapy
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Figure 0007: The MR of abdominal wall (A, B) before, and (C, D) 3 weeks after brachytherapy

Mentions: During the follow-up examination in the 3rd week after brachytherapy, remission of the metastatic cancer was observed. The abdominal wall mass had disappeared according to the MR results (see Fig. 7). During the follow-up visit (2 months after therapy), only radiation-induced skin injury (RTOG, Grade 1) was observed. According to the recent follow-up over 5 months after therapy, there were no signs or symptoms of abdominal complications and no evidence of recurrence at the site of re-irradiation. Chemotherapy will be continued depending on the personal tolerance and general patient condition.


A case report of ultrasound-guided interstitial brachytherapy for abdominal wall metastases of ovarian cancer.

Shi D, Wu N, Zhao H, He M, Han D, Cheng G - J Contemp Brachytherapy (2015)

The MR of abdominal wall (A, B) before, and (C, D) 3 weeks after brachytherapy
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4371059&req=5

Figure 0007: The MR of abdominal wall (A, B) before, and (C, D) 3 weeks after brachytherapy
Mentions: During the follow-up examination in the 3rd week after brachytherapy, remission of the metastatic cancer was observed. The abdominal wall mass had disappeared according to the MR results (see Fig. 7). During the follow-up visit (2 months after therapy), only radiation-induced skin injury (RTOG, Grade 1) was observed. According to the recent follow-up over 5 months after therapy, there were no signs or symptoms of abdominal complications and no evidence of recurrence at the site of re-irradiation. Chemotherapy will be continued depending on the personal tolerance and general patient condition.

Bottom Line: The patient is a 44-year-old female with a diagnosis of stage IA ovarian cancer.After surgery and two cycles of chemotherapy with paclitaxel and carboplatin, the patient noticed dull pain in the lower abdomen and found a mass located in the subcutaneous tissue, below the operative incision.A diagnostic biopsy showed abdominal wall metastases.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun, China ; These two authors contributed equally to this work.

ABSTRACT

Purpose: To report the treatment effect of interstitial brachytherapy for abdominal wall metastases of ovarian cancer.

Material and methods: The patient is a 44-year-old female with a diagnosis of stage IA ovarian cancer. After surgery and two cycles of chemotherapy with paclitaxel and carboplatin, the patient noticed dull pain in the lower abdomen and found a mass located in the subcutaneous tissue, below the operative incision. A diagnostic biopsy showed abdominal wall metastases. After external radiotherapy with a dose of 39.6 Gy in 22 fractions, the residual tumor was treated with interstitial brachytherapy under ultrasound guidance. The brachytherapy dose was 18 Gy in 6 fractions of 3 Gy each.

Results: After 3 weeks of brachytherapy, the tumor had disappeared completely. Interstitial brachytherapy was feasible.

Conclusions: Interstitial brachytherapy may be a proposed treatment strategy for inoperable superficial metastases, especially for low radiosensitivity cancer.

No MeSH data available.


Related in: MedlinePlus