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Screening for major depressive disorder with the Patient Health Questionnaire (PHQ-9 and PHQ-2) in an outpatient clinic staffed by primary care physicians in Japan: a case control study.

Suzuki K, Kumei S, Ohhira M, Nozu T, Okumura T - PLoS ONE (2015)

Bottom Line: The best cut-off points for the PHQ-9 and PHQ-2 summary scores were ≥11 (sensitivity 0.76, specificity 0.81) and ≥3 (sensitivity 0.76, specificity 0.82), respectively.No relationship was observed between the age and PHQ-9 scores.The PHQ-9 and PHQ-2 were useful instruments for screening for major depressive disorders.

View Article: PubMed Central - PubMed

Affiliation: Department of General Medicine, Asahikawa University Hospital, Asahikawa, Hokkaido, Japan; Department of General Internal Medicine, Asahikawa City Hospital, Asahikawa, Hokkaido, Japan.

ABSTRACT

Objective: The Patient Health Questionnaire (PHQ-9) is a self-report questionnaire commonly used to screen for depression, with ≥8-11 generally recommended as the cut-off. In Japan, studies of the validity of the PHQ-9 and PHQ-2 have been limited. In this study, we examined the utility of the PHQ-9 and PHQ-2 at an outpatient clinic in a Medical University Hospital in Japan.

Methods: New consecutive outpatients were included in the study. We administered the PHQ-9 to 574 patients, and acquired complete PHQ-9 and PHQ-2 data for 521 patients. Major depressive disorders were diagnosed according to the DSM-IV-TR.

Results: Forty-two patients were diagnosed with major depressive disorders. The mean PHQ-9 (15.7) and PHQ-2 (3.8) scores of the patients with major depressive disorders were significantly higher than the scores of the patients without depression (6.0 (PHQ-9) and 1.8 (PHQ-2)). The best cut-off points for the PHQ-9 and PHQ-2 summary scores were ≥11 (sensitivity 0.76, specificity 0.81) and ≥3 (sensitivity 0.76, specificity 0.82), respectively. No relationship was observed between the age and PHQ-9 scores.

Conclusion: The PHQ-9 and PHQ-2 were useful instruments for screening for major depressive disorders. The best cut-off point for the PHQ-9 summary score should be ≥11 to detect depression in the primary care setting in Japan.

No MeSH data available.


Related in: MedlinePlus

The relationship between the age and PHQ-9 total scores of the patients.ND: non-depressed, D: depressed.
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pone.0119147.g002: The relationship between the age and PHQ-9 total scores of the patients.ND: non-depressed, D: depressed.

Mentions: Fig. 2 shows the relationship between the age and the PHQ-9 total scores. The Pearson’s product-moment correlation revealed no correlation between age and the PHQ-9 total scores in not only depressed patients, but also in patients without depression.


Screening for major depressive disorder with the Patient Health Questionnaire (PHQ-9 and PHQ-2) in an outpatient clinic staffed by primary care physicians in Japan: a case control study.

Suzuki K, Kumei S, Ohhira M, Nozu T, Okumura T - PLoS ONE (2015)

The relationship between the age and PHQ-9 total scores of the patients.ND: non-depressed, D: depressed.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4366166&req=5

pone.0119147.g002: The relationship between the age and PHQ-9 total scores of the patients.ND: non-depressed, D: depressed.
Mentions: Fig. 2 shows the relationship between the age and the PHQ-9 total scores. The Pearson’s product-moment correlation revealed no correlation between age and the PHQ-9 total scores in not only depressed patients, but also in patients without depression.

Bottom Line: The best cut-off points for the PHQ-9 and PHQ-2 summary scores were ≥11 (sensitivity 0.76, specificity 0.81) and ≥3 (sensitivity 0.76, specificity 0.82), respectively.No relationship was observed between the age and PHQ-9 scores.The PHQ-9 and PHQ-2 were useful instruments for screening for major depressive disorders.

View Article: PubMed Central - PubMed

Affiliation: Department of General Medicine, Asahikawa University Hospital, Asahikawa, Hokkaido, Japan; Department of General Internal Medicine, Asahikawa City Hospital, Asahikawa, Hokkaido, Japan.

ABSTRACT

Objective: The Patient Health Questionnaire (PHQ-9) is a self-report questionnaire commonly used to screen for depression, with ≥8-11 generally recommended as the cut-off. In Japan, studies of the validity of the PHQ-9 and PHQ-2 have been limited. In this study, we examined the utility of the PHQ-9 and PHQ-2 at an outpatient clinic in a Medical University Hospital in Japan.

Methods: New consecutive outpatients were included in the study. We administered the PHQ-9 to 574 patients, and acquired complete PHQ-9 and PHQ-2 data for 521 patients. Major depressive disorders were diagnosed according to the DSM-IV-TR.

Results: Forty-two patients were diagnosed with major depressive disorders. The mean PHQ-9 (15.7) and PHQ-2 (3.8) scores of the patients with major depressive disorders were significantly higher than the scores of the patients without depression (6.0 (PHQ-9) and 1.8 (PHQ-2)). The best cut-off points for the PHQ-9 and PHQ-2 summary scores were ≥11 (sensitivity 0.76, specificity 0.81) and ≥3 (sensitivity 0.76, specificity 0.82), respectively. No relationship was observed between the age and PHQ-9 scores.

Conclusion: The PHQ-9 and PHQ-2 were useful instruments for screening for major depressive disorders. The best cut-off point for the PHQ-9 summary score should be ≥11 to detect depression in the primary care setting in Japan.

No MeSH data available.


Related in: MedlinePlus