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The value of spirometry and exercise challenge test to diagnose and monitor children with asthma.

van den Wijngaart LS, Roukema J, Merkus PJ - Respirol Case Rep (2015)

Bottom Line: Asthma is defined as a chronic inflammatory disease of the airways with characteristic symptoms including recurrent episodes of wheezing, breathlessness, chest tightness, and coughing.It may result in abnormalities of ventilator function, which can be assessed by different pulmonary function tests.In this case report, we present a 15-year-old boy with asthma and illustrate the value and limitations of spirometry and exercise challenge test in daily practice.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Division of Respiratory Medicine, Radboud University Medical Centre, Amalia Children's Hospital Nijmegen, The Netherlands.

ABSTRACT
Asthma is defined as a chronic inflammatory disease of the airways with characteristic symptoms including recurrent episodes of wheezing, breathlessness, chest tightness, and coughing. It may result in abnormalities of ventilator function, which can be assessed by different pulmonary function tests. In this case report, we present a 15-year-old boy with asthma and illustrate the value and limitations of spirometry and exercise challenge test in daily practice.

No MeSH data available.


Related in: MedlinePlus

Reversible obstruction after 5 days of treatment with systemic corticosteroids. Blue curve (pre-bronchodilation): Forced vital capacity (FVC) 4.62 L (99% of predicted), forced expiratory volume in 1 sec (FEV1) 3.73 L (96% of predicted), FEV1/FVC 81% (97% of predicted), maximum midexpiratory flow (FEV0.25–0.75) 3.40 L (79% of predicted). Red curve (post-bronchodilation): FVC 4.79 L (103% of predicted), FEV1 3.95 L (102% of predicted), FEV1/FVC 83% (99% of predicted), maximum midexpiratory flow (FEV0.25–0.75) 3.68 L (90% of predicted).
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fig03: Reversible obstruction after 5 days of treatment with systemic corticosteroids. Blue curve (pre-bronchodilation): Forced vital capacity (FVC) 4.62 L (99% of predicted), forced expiratory volume in 1 sec (FEV1) 3.73 L (96% of predicted), FEV1/FVC 81% (97% of predicted), maximum midexpiratory flow (FEV0.25–0.75) 3.40 L (79% of predicted). Red curve (post-bronchodilation): FVC 4.79 L (103% of predicted), FEV1 3.95 L (102% of predicted), FEV1/FVC 83% (99% of predicted), maximum midexpiratory flow (FEV0.25–0.75) 3.68 L (90% of predicted).

Mentions: At a regular visit a week later, he still had no complaints of dyspnea in rest. However, auscultation revealed diminished breath sounds with a prolonged expirium. Spirometry results confirmed a rather severe airways obstruction (Figure 2). He was treated with systemic corticosteroids (prednisolone 40 mg twice daily for 5 days) and frequent use of beta-2 mimetics (salbutamol). Spirometry was repeated after 1 week (Figure 3), showing an improved flow-volume loop.


The value of spirometry and exercise challenge test to diagnose and monitor children with asthma.

van den Wijngaart LS, Roukema J, Merkus PJ - Respirol Case Rep (2015)

Reversible obstruction after 5 days of treatment with systemic corticosteroids. Blue curve (pre-bronchodilation): Forced vital capacity (FVC) 4.62 L (99% of predicted), forced expiratory volume in 1 sec (FEV1) 3.73 L (96% of predicted), FEV1/FVC 81% (97% of predicted), maximum midexpiratory flow (FEV0.25–0.75) 3.40 L (79% of predicted). Red curve (post-bronchodilation): FVC 4.79 L (103% of predicted), FEV1 3.95 L (102% of predicted), FEV1/FVC 83% (99% of predicted), maximum midexpiratory flow (FEV0.25–0.75) 3.68 L (90% of predicted).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4364795&req=5

fig03: Reversible obstruction after 5 days of treatment with systemic corticosteroids. Blue curve (pre-bronchodilation): Forced vital capacity (FVC) 4.62 L (99% of predicted), forced expiratory volume in 1 sec (FEV1) 3.73 L (96% of predicted), FEV1/FVC 81% (97% of predicted), maximum midexpiratory flow (FEV0.25–0.75) 3.40 L (79% of predicted). Red curve (post-bronchodilation): FVC 4.79 L (103% of predicted), FEV1 3.95 L (102% of predicted), FEV1/FVC 83% (99% of predicted), maximum midexpiratory flow (FEV0.25–0.75) 3.68 L (90% of predicted).
Mentions: At a regular visit a week later, he still had no complaints of dyspnea in rest. However, auscultation revealed diminished breath sounds with a prolonged expirium. Spirometry results confirmed a rather severe airways obstruction (Figure 2). He was treated with systemic corticosteroids (prednisolone 40 mg twice daily for 5 days) and frequent use of beta-2 mimetics (salbutamol). Spirometry was repeated after 1 week (Figure 3), showing an improved flow-volume loop.

Bottom Line: Asthma is defined as a chronic inflammatory disease of the airways with characteristic symptoms including recurrent episodes of wheezing, breathlessness, chest tightness, and coughing.It may result in abnormalities of ventilator function, which can be assessed by different pulmonary function tests.In this case report, we present a 15-year-old boy with asthma and illustrate the value and limitations of spirometry and exercise challenge test in daily practice.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Division of Respiratory Medicine, Radboud University Medical Centre, Amalia Children's Hospital Nijmegen, The Netherlands.

ABSTRACT
Asthma is defined as a chronic inflammatory disease of the airways with characteristic symptoms including recurrent episodes of wheezing, breathlessness, chest tightness, and coughing. It may result in abnormalities of ventilator function, which can be assessed by different pulmonary function tests. In this case report, we present a 15-year-old boy with asthma and illustrate the value and limitations of spirometry and exercise challenge test in daily practice.

No MeSH data available.


Related in: MedlinePlus