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Clinical applications of anterior segment optical coherence tomography.

Lim SH - J Ophthalmol (2015)

Bottom Line: Anterior segment optical coherence tomography (AS-OCT) was recently developed and has become a crucial tool in clinical practice.AS-OCT is a noncontact imaging device that provides the detailed structure of the anterior part of the eyes.The author also presents some interesting cases demonstrated via AS-OCT.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Yeungnam University College of Medicine, Daegu, Republic of Korea ; Department of Ophthalmology, Daegu Veterans Health Service Medical Center, 60 Wolgok-ro, Dalseo-Gu, Daegu 704-802, Republic of Korea.

ABSTRACT
Anterior segment optical coherence tomography (AS-OCT) was recently developed and has become a crucial tool in clinical practice. AS-OCT is a noncontact imaging device that provides the detailed structure of the anterior part of the eyes. In this review, the author will discuss the various clinical applications of AS-OCT, such as the normal findings, tear meniscus measurement, ocular surface disease (e.g., pterygium, pinguecula, and scleromalacia), architectural analysis after cataract surgery, post-LASIK keratectasia, Descemet's membrane detachment, evaluation of corneal graft after keratoplasty, corneal deposits (corneal dystrophies and corneal verticillata), keratitis, anterior segment tumors, and glaucoma evaluation (angle assessment, morphological analysis of the filtering bleb after trabeculectomy, or glaucoma drainage device implantation surgery). The author also presents some interesting cases demonstrated via AS-OCT.

No MeSH data available.


Related in: MedlinePlus

Anterior segment OCT images after trabeculectomies. Vertical and horizontal OCT sections (left column) demonstrate various parameters: internal cavity extent (a), bleb height (b), internal cavity height (c), and bleb wall thickness (d). Right upper images demonstrate thick bleb wall and high internal reflectivity suggesting bleb failure. Right lower images demonstrate relatively thin bleb wall and multiple-layer appearance with low internal reflectivity with good IOP control.
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fig12: Anterior segment OCT images after trabeculectomies. Vertical and horizontal OCT sections (left column) demonstrate various parameters: internal cavity extent (a), bleb height (b), internal cavity height (c), and bleb wall thickness (d). Right upper images demonstrate thick bleb wall and high internal reflectivity suggesting bleb failure. Right lower images demonstrate relatively thin bleb wall and multiple-layer appearance with low internal reflectivity with good IOP control.

Mentions: Although OCT was not developed to evaluate the filtering bleb, AS-OCT can visualize filtering blebs and can reveal the details of their morphology (Figure 12) [61]. Many articles have described the association of the bleb morphology and IOP control. Nakano et al. [62] predicted bleb failure based on the bleb wall uniformity in developing bleb after trabeculectomy. They reported that the multiple-layer appearance had a good bleb function after six months. Tominaga et al. [63] also stated that the low-reflectivity wall and the presence of episcleral fluid were associated with good IOP controls after trabeculectomy. Pfenninger et al. [64] demonstrated the correlation between the internal reflectivity of the fluid-filled cavity and IOP control after the recent trabeculectomy. The AS-OCT results, however, revealed no significant association between reflectivity and IOP control in Ahmed glaucoma valve (AGV) surgeries, and the maximum bleb wall was thinner in the surgical success group compared with the surgical failure group [65]. Recently, the 3D AS-OCT technique allows a detailed evaluation of the internal morphology of filtering blebs and precise identification of the filtration opening on the scleral flap margin after trabeculectomy [66].


Clinical applications of anterior segment optical coherence tomography.

Lim SH - J Ophthalmol (2015)

Anterior segment OCT images after trabeculectomies. Vertical and horizontal OCT sections (left column) demonstrate various parameters: internal cavity extent (a), bleb height (b), internal cavity height (c), and bleb wall thickness (d). Right upper images demonstrate thick bleb wall and high internal reflectivity suggesting bleb failure. Right lower images demonstrate relatively thin bleb wall and multiple-layer appearance with low internal reflectivity with good IOP control.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4363581&req=5

fig12: Anterior segment OCT images after trabeculectomies. Vertical and horizontal OCT sections (left column) demonstrate various parameters: internal cavity extent (a), bleb height (b), internal cavity height (c), and bleb wall thickness (d). Right upper images demonstrate thick bleb wall and high internal reflectivity suggesting bleb failure. Right lower images demonstrate relatively thin bleb wall and multiple-layer appearance with low internal reflectivity with good IOP control.
Mentions: Although OCT was not developed to evaluate the filtering bleb, AS-OCT can visualize filtering blebs and can reveal the details of their morphology (Figure 12) [61]. Many articles have described the association of the bleb morphology and IOP control. Nakano et al. [62] predicted bleb failure based on the bleb wall uniformity in developing bleb after trabeculectomy. They reported that the multiple-layer appearance had a good bleb function after six months. Tominaga et al. [63] also stated that the low-reflectivity wall and the presence of episcleral fluid were associated with good IOP controls after trabeculectomy. Pfenninger et al. [64] demonstrated the correlation between the internal reflectivity of the fluid-filled cavity and IOP control after the recent trabeculectomy. The AS-OCT results, however, revealed no significant association between reflectivity and IOP control in Ahmed glaucoma valve (AGV) surgeries, and the maximum bleb wall was thinner in the surgical success group compared with the surgical failure group [65]. Recently, the 3D AS-OCT technique allows a detailed evaluation of the internal morphology of filtering blebs and precise identification of the filtration opening on the scleral flap margin after trabeculectomy [66].

Bottom Line: Anterior segment optical coherence tomography (AS-OCT) was recently developed and has become a crucial tool in clinical practice.AS-OCT is a noncontact imaging device that provides the detailed structure of the anterior part of the eyes.The author also presents some interesting cases demonstrated via AS-OCT.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Yeungnam University College of Medicine, Daegu, Republic of Korea ; Department of Ophthalmology, Daegu Veterans Health Service Medical Center, 60 Wolgok-ro, Dalseo-Gu, Daegu 704-802, Republic of Korea.

ABSTRACT
Anterior segment optical coherence tomography (AS-OCT) was recently developed and has become a crucial tool in clinical practice. AS-OCT is a noncontact imaging device that provides the detailed structure of the anterior part of the eyes. In this review, the author will discuss the various clinical applications of AS-OCT, such as the normal findings, tear meniscus measurement, ocular surface disease (e.g., pterygium, pinguecula, and scleromalacia), architectural analysis after cataract surgery, post-LASIK keratectasia, Descemet's membrane detachment, evaluation of corneal graft after keratoplasty, corneal deposits (corneal dystrophies and corneal verticillata), keratitis, anterior segment tumors, and glaucoma evaluation (angle assessment, morphological analysis of the filtering bleb after trabeculectomy, or glaucoma drainage device implantation surgery). The author also presents some interesting cases demonstrated via AS-OCT.

No MeSH data available.


Related in: MedlinePlus