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Hemato-biochemical responses to packing in donkeys administered ascorbic acid during the harmattan season.

Olaifa F, Ayo JO, Ambali SF, Rekwot PI - J. Vet. Med. Sci. (2012)

Bottom Line: Experiments were performed to investigate the effect of ascorbic acid (AA) in reducing hemato-biochemical changes in pack donkeys during the cold-dry (harmattan) season.The eosinophil count increased significantly (P<0.05) in experimental and control donkeys post packing.In conclusion, packing exerted significant adverse effects on the hematological parameters ameliorated by AA administration.

View Article: PubMed Central - PubMed

Affiliation: Department of Veterinary Physiology and Pharmacology, Ahmadu Bello University, Zaria, Nigeria.

ABSTRACT
Experiments were performed to investigate the effect of ascorbic acid (AA) in reducing hemato-biochemical changes in pack donkeys during the cold-dry (harmattan) season. Six experimental donkeys administered orally AA (200 mg/kg) and six control donkeys not administered ascorbic acid were subjected to packing. Blood samples were collected from all donkeys for hematological and biochemical analyses. In the control donkeys, packed cell volume (PCV), erythrocyte count and hemoglobin concentration (Hb) decreased significantly (P<0.05) at the end of packing. In the experimental donkeys, there was no significant difference between the pre- and post-packing values of PCV, erythrocyte count and Hb. In the control donkeys, the neutrophil and neutrophil:lymphocyte ratio increased significantly (P<0.05) post packing, but in the experimental donkeys, the pre- and post-packing values were not significantly different. The eosinophil count increased significantly (P<0.05) in experimental and control donkeys post packing. In conclusion, packing exerted significant adverse effects on the hematological parameters ameliorated by AA administration. AA may modulate neutrophilia and induce a considerable alteration of erythroid markers in donkeys subjected to packing during the harmattan season.

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a) Total leukocyte counts (Leukocytes) and differential leukocyte counts (Neutrophils, Lymphocytes, Monocytes and Eosinophils) of donkeys administered ascorbic acid (Experimental) and donkeys not administered ascorbic acid (Control). The white columns represent pre-packing values (n=6). The black columns represent post packing (n=6). Total leukocyte counts and differential leucocyte counts were measured as described in section 2. Values and bars are the mean ± SE (n=6) and P<0.05. b) Neutrophil:lymphocyte ratio of donkeys administered ascorbic acid (Experimental) and donkeys not administered ascorbic acid (Control). The white columns represent pre-packing values (n=6). The black columns represent post packing values (n=6). Neutrophil:lymphocyte ratio was measured as described in section 2. Values and bars are the mean ± SE (n=6) and P<0.05.
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fig_002: a) Total leukocyte counts (Leukocytes) and differential leukocyte counts (Neutrophils, Lymphocytes, Monocytes and Eosinophils) of donkeys administered ascorbic acid (Experimental) and donkeys not administered ascorbic acid (Control). The white columns represent pre-packing values (n=6). The black columns represent post packing (n=6). Total leukocyte counts and differential leucocyte counts were measured as described in section 2. Values and bars are the mean ± SE (n=6) and P<0.05. b) Neutrophil:lymphocyte ratio of donkeys administered ascorbic acid (Experimental) and donkeys not administered ascorbic acid (Control). The white columns represent pre-packing values (n=6). The black columns represent post packing values (n=6). Neutrophil:lymphocyte ratio was measured as described in section 2. Values and bars are the mean ± SE (n=6) and P<0.05.

Mentions: There were no significant changes between the pre- and post-packing total leukocyte counts obtained in each group (Fig. 2aFig. 2.


Hemato-biochemical responses to packing in donkeys administered ascorbic acid during the harmattan season.

Olaifa F, Ayo JO, Ambali SF, Rekwot PI - J. Vet. Med. Sci. (2012)

a) Total leukocyte counts (Leukocytes) and differential leukocyte counts (Neutrophils, Lymphocytes, Monocytes and Eosinophils) of donkeys administered ascorbic acid (Experimental) and donkeys not administered ascorbic acid (Control). The white columns represent pre-packing values (n=6). The black columns represent post packing (n=6). Total leukocyte counts and differential leucocyte counts were measured as described in section 2. Values and bars are the mean ± SE (n=6) and P<0.05. b) Neutrophil:lymphocyte ratio of donkeys administered ascorbic acid (Experimental) and donkeys not administered ascorbic acid (Control). The white columns represent pre-packing values (n=6). The black columns represent post packing values (n=6). Neutrophil:lymphocyte ratio was measured as described in section 2. Values and bars are the mean ± SE (n=6) and P<0.05.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4363013&req=5

fig_002: a) Total leukocyte counts (Leukocytes) and differential leukocyte counts (Neutrophils, Lymphocytes, Monocytes and Eosinophils) of donkeys administered ascorbic acid (Experimental) and donkeys not administered ascorbic acid (Control). The white columns represent pre-packing values (n=6). The black columns represent post packing (n=6). Total leukocyte counts and differential leucocyte counts were measured as described in section 2. Values and bars are the mean ± SE (n=6) and P<0.05. b) Neutrophil:lymphocyte ratio of donkeys administered ascorbic acid (Experimental) and donkeys not administered ascorbic acid (Control). The white columns represent pre-packing values (n=6). The black columns represent post packing values (n=6). Neutrophil:lymphocyte ratio was measured as described in section 2. Values and bars are the mean ± SE (n=6) and P<0.05.
Mentions: There were no significant changes between the pre- and post-packing total leukocyte counts obtained in each group (Fig. 2aFig. 2.

Bottom Line: Experiments were performed to investigate the effect of ascorbic acid (AA) in reducing hemato-biochemical changes in pack donkeys during the cold-dry (harmattan) season.The eosinophil count increased significantly (P<0.05) in experimental and control donkeys post packing.In conclusion, packing exerted significant adverse effects on the hematological parameters ameliorated by AA administration.

View Article: PubMed Central - PubMed

Affiliation: Department of Veterinary Physiology and Pharmacology, Ahmadu Bello University, Zaria, Nigeria.

ABSTRACT
Experiments were performed to investigate the effect of ascorbic acid (AA) in reducing hemato-biochemical changes in pack donkeys during the cold-dry (harmattan) season. Six experimental donkeys administered orally AA (200 mg/kg) and six control donkeys not administered ascorbic acid were subjected to packing. Blood samples were collected from all donkeys for hematological and biochemical analyses. In the control donkeys, packed cell volume (PCV), erythrocyte count and hemoglobin concentration (Hb) decreased significantly (P<0.05) at the end of packing. In the experimental donkeys, there was no significant difference between the pre- and post-packing values of PCV, erythrocyte count and Hb. In the control donkeys, the neutrophil and neutrophil:lymphocyte ratio increased significantly (P<0.05) post packing, but in the experimental donkeys, the pre- and post-packing values were not significantly different. The eosinophil count increased significantly (P<0.05) in experimental and control donkeys post packing. In conclusion, packing exerted significant adverse effects on the hematological parameters ameliorated by AA administration. AA may modulate neutrophilia and induce a considerable alteration of erythroid markers in donkeys subjected to packing during the harmattan season.

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