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Multiple myeloma presenting with a maxillary lesion as the first sign.

Ramaiah KK, Joshi V, Thayi SR, Sathyanarayana P, Patil P, Ahmed Z - Imaging Sci Dent (2015)

Bottom Line: The mass had become enlarged after the teeth were extracted 15 days previously.Radiographs demonstrated multiple punched-out radiolucent lesions in the skull and pelvic region.Computed tomography images showed a soft tissue density mass in the left maxilla, eroding the floor and walls of the maxillary sinus.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Medicine and Radiology, Navodaya Dental College and Hospital, Raichur, India.

ABSTRACT
Multiple myeloma is a clonal neoplastic proliferation of terminally differentiated B-lymphocytes involving the skeletal system in a multifocal fashion. Its oral manifestations are less common in the maxilla than in the mandible due to the lower amount of hemopoietic bone marrow in the maxilla. We report the case of a 50-year-old man who presented with a mass in the left maxillary alveolar region with tooth mobility. The mass had become enlarged after the teeth were extracted 15 days previously. Radiographs demonstrated multiple punched-out radiolucent lesions in the skull and pelvic region. Computed tomography images showed a soft tissue density mass in the left maxilla, eroding the floor and walls of the maxillary sinus. Although several analytical techniques were used to characterize the lesion, it was finally confirmed as multiple myeloma through immunohistochemistry.

No MeSH data available.


Related in: MedlinePlus

An extraoral photograph shows diffuse swelling in the left middle third of the face.
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Figure 1: An extraoral photograph shows diffuse swelling in the left middle third of the face.

Mentions: A 50-year-old man presented with a diffuse swelling in the left maxillary alveolar region with mobility of the adjacent teeth. The upper left first and second molars had been extracted 15 days previously due to pain; following the extraction, the lesion became enlarged (Fig. 1). Diffuse swelling in the left maxillary region had obliterated the left nasolabial fold extraorally. A sessile, soft, non-pulsatile, non-tender, non-hemorrhagic intraoral mass extended from the left maxillary second premolar to the tuberosity region, and extended medially up to the midpalatine raphe (Fig. 2). The lymph nodes were not palpable. The clinically considered differential diagnoses were carcinoma of the maxillary sinus and metastatic carcinoma.


Multiple myeloma presenting with a maxillary lesion as the first sign.

Ramaiah KK, Joshi V, Thayi SR, Sathyanarayana P, Patil P, Ahmed Z - Imaging Sci Dent (2015)

An extraoral photograph shows diffuse swelling in the left middle third of the face.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4362992&req=5

Figure 1: An extraoral photograph shows diffuse swelling in the left middle third of the face.
Mentions: A 50-year-old man presented with a diffuse swelling in the left maxillary alveolar region with mobility of the adjacent teeth. The upper left first and second molars had been extracted 15 days previously due to pain; following the extraction, the lesion became enlarged (Fig. 1). Diffuse swelling in the left maxillary region had obliterated the left nasolabial fold extraorally. A sessile, soft, non-pulsatile, non-tender, non-hemorrhagic intraoral mass extended from the left maxillary second premolar to the tuberosity region, and extended medially up to the midpalatine raphe (Fig. 2). The lymph nodes were not palpable. The clinically considered differential diagnoses were carcinoma of the maxillary sinus and metastatic carcinoma.

Bottom Line: The mass had become enlarged after the teeth were extracted 15 days previously.Radiographs demonstrated multiple punched-out radiolucent lesions in the skull and pelvic region.Computed tomography images showed a soft tissue density mass in the left maxilla, eroding the floor and walls of the maxillary sinus.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Medicine and Radiology, Navodaya Dental College and Hospital, Raichur, India.

ABSTRACT
Multiple myeloma is a clonal neoplastic proliferation of terminally differentiated B-lymphocytes involving the skeletal system in a multifocal fashion. Its oral manifestations are less common in the maxilla than in the mandible due to the lower amount of hemopoietic bone marrow in the maxilla. We report the case of a 50-year-old man who presented with a mass in the left maxillary alveolar region with tooth mobility. The mass had become enlarged after the teeth were extracted 15 days previously. Radiographs demonstrated multiple punched-out radiolucent lesions in the skull and pelvic region. Computed tomography images showed a soft tissue density mass in the left maxilla, eroding the floor and walls of the maxillary sinus. Although several analytical techniques were used to characterize the lesion, it was finally confirmed as multiple myeloma through immunohistochemistry.

No MeSH data available.


Related in: MedlinePlus