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Intravenous contrast media application using cone-beam computed tomography in a rabbit model.

Kim MS, Kim BY, Choi HY, Choi YJ, Oh SH, Kang JH, Lee SR, Kang JH, Kim GT, Choi YS, Hwang EH - Imaging Sci Dent (2015)

Bottom Line: An adequate contrast medium injection parameter for facilitating effective CE-CBCT was a 5-mL injection before exposure combined with a continuous 5-mL injection during scanning.The CE-CBCT images demonstrated adequate opacification of the soft tissues and vascular structures.The vascular structures and soft tissue lesions appeared well delineated in the CE-CBCT images, which was probably due to the superior spatial resolution of CE-CBCT compared to other techniques, such as multislice computed tomography.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral and Maxillofacial Radiology, School of Dentistry, Kyung Hee University, Seoul, Korea.

ABSTRACT

Purpose: This study was performed to evaluate the feasibility of visualizing soft tissue lesions and vascular structures using contrast-enhanced cone-beam computed tomography (CE-CBCT) after the intravenous administration of a contrast medium in an animal model.

Materials and methods: CBCT was performed on six rabbits after a contrast medium was administered using an injection dose of 2 mL/kg body weight and an injection rate of 1 mL/s via the ear vein or femoral vein under general anesthesia. Artificial soft tissue lesions were created through the transplantation of autologous fatty tissue into the salivary gland. Volume rendering reconstruction, maximum intensity projection, and multiplanar reconstruction images were reconstructed and evaluated in order to visualize soft tissue contrast and vascular structures.

Results: The contrast enhancement of soft tissue was possible using all contrast medium injection parameters. An adequate contrast medium injection parameter for facilitating effective CE-CBCT was a 5-mL injection before exposure combined with a continuous 5-mL injection during scanning. Artificial soft tissue lesions were successfully created in the animals. The CE-CBCT images demonstrated adequate opacification of the soft tissues and vascular structures.

Conclusion: Despite limited soft tissue resolution, the opacification of vascular structures was observed and artificial soft tissue lesions were visualized with sufficient contrast to the surrounding structures. The vascular structures and soft tissue lesions appeared well delineated in the CE-CBCT images, which was probably due to the superior spatial resolution of CE-CBCT compared to other techniques, such as multislice computed tomography.

No MeSH data available.


Related in: MedlinePlus

The graph shows the contrast density in CBCT according to the study protocol of the contrast media administration for contrast enhancement.
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Figure 8: The graph shows the contrast density in CBCT according to the study protocol of the contrast media administration for contrast enhancement.

Mentions: The anatomy of the carotid arteries and the nutrient vessels to the SMGs in the neck region was clearly visible in all modalities. Subsequently, both reviewers determined that all VRT images obtained by CBCT were of good diagnostic quality. Type 3 reconstructed CBCT MIP images were assessed to evaluate variation among the different methods of administrating the contrast medium. The delineation of vessels and SMGs was sharper in Type 3 images, and therefore the borders of the nutrient vessels and the anatomy of the SMGs were much more visible, indicating sharp contrast enhancement. The results of the measurements are given in Figure 8.


Intravenous contrast media application using cone-beam computed tomography in a rabbit model.

Kim MS, Kim BY, Choi HY, Choi YJ, Oh SH, Kang JH, Lee SR, Kang JH, Kim GT, Choi YS, Hwang EH - Imaging Sci Dent (2015)

The graph shows the contrast density in CBCT according to the study protocol of the contrast media administration for contrast enhancement.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4362989&req=5

Figure 8: The graph shows the contrast density in CBCT according to the study protocol of the contrast media administration for contrast enhancement.
Mentions: The anatomy of the carotid arteries and the nutrient vessels to the SMGs in the neck region was clearly visible in all modalities. Subsequently, both reviewers determined that all VRT images obtained by CBCT were of good diagnostic quality. Type 3 reconstructed CBCT MIP images were assessed to evaluate variation among the different methods of administrating the contrast medium. The delineation of vessels and SMGs was sharper in Type 3 images, and therefore the borders of the nutrient vessels and the anatomy of the SMGs were much more visible, indicating sharp contrast enhancement. The results of the measurements are given in Figure 8.

Bottom Line: An adequate contrast medium injection parameter for facilitating effective CE-CBCT was a 5-mL injection before exposure combined with a continuous 5-mL injection during scanning.The CE-CBCT images demonstrated adequate opacification of the soft tissues and vascular structures.The vascular structures and soft tissue lesions appeared well delineated in the CE-CBCT images, which was probably due to the superior spatial resolution of CE-CBCT compared to other techniques, such as multislice computed tomography.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral and Maxillofacial Radiology, School of Dentistry, Kyung Hee University, Seoul, Korea.

ABSTRACT

Purpose: This study was performed to evaluate the feasibility of visualizing soft tissue lesions and vascular structures using contrast-enhanced cone-beam computed tomography (CE-CBCT) after the intravenous administration of a contrast medium in an animal model.

Materials and methods: CBCT was performed on six rabbits after a contrast medium was administered using an injection dose of 2 mL/kg body weight and an injection rate of 1 mL/s via the ear vein or femoral vein under general anesthesia. Artificial soft tissue lesions were created through the transplantation of autologous fatty tissue into the salivary gland. Volume rendering reconstruction, maximum intensity projection, and multiplanar reconstruction images were reconstructed and evaluated in order to visualize soft tissue contrast and vascular structures.

Results: The contrast enhancement of soft tissue was possible using all contrast medium injection parameters. An adequate contrast medium injection parameter for facilitating effective CE-CBCT was a 5-mL injection before exposure combined with a continuous 5-mL injection during scanning. Artificial soft tissue lesions were successfully created in the animals. The CE-CBCT images demonstrated adequate opacification of the soft tissues and vascular structures.

Conclusion: Despite limited soft tissue resolution, the opacification of vascular structures was observed and artificial soft tissue lesions were visualized with sufficient contrast to the surrounding structures. The vascular structures and soft tissue lesions appeared well delineated in the CE-CBCT images, which was probably due to the superior spatial resolution of CE-CBCT compared to other techniques, such as multislice computed tomography.

No MeSH data available.


Related in: MedlinePlus