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The role of PET-CT in radiotherapy planning of solid tumours.

Jelercic S, Rajer M - Radiol Oncol (2015)

Bottom Line: PET-CT is becoming more and more important in various aspects of oncology.Until recently it was used mainly as part of diagnostic procedures and for evaluation of treatment results.Standard anatomical imaging used to select and delineate RT target volumes can be enriched by the information on tumour biology gained by PET-CT.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiotherapy, Institute of Oncology Ljubljana, Ljubljana, Slovenia.

ABSTRACT

Background: PET-CT is becoming more and more important in various aspects of oncology. Until recently it was used mainly as part of diagnostic procedures and for evaluation of treatment results. With development of personalized radiotherapy, volumetric and radiobiological characteristics of individual tumour have become integrated in the multistep radiotherapy (RT) planning process. Standard anatomical imaging used to select and delineate RT target volumes can be enriched by the information on tumour biology gained by PET-CT. In this review we explore the current and possible future role of PET-CT in radiotherapy treatment planning. After general explanation, we assess its role in radiotherapy of those solid tumours for which PET-CT is being used most.

Conclusions: In the nearby future PET-CT will be an integral part of the most radiotherapy treatment planning procedures in an every-day clinical practice. Apart from a clear role in radiation planning of lung cancer, with forthcoming clinical trials, we will get more evidence of the optimal use of PET-CT in radiotherapy planning of other solid tumours.

No MeSH data available.


Related in: MedlinePlus

PET-CT images of 51-year old male with metastatic squamous cell carcinoma of unknown origin in cervical lymph nodes. The origin was found by PET-CT and later confirmed by a biopsy.
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f2-rado-49-01-01: PET-CT images of 51-year old male with metastatic squamous cell carcinoma of unknown origin in cervical lymph nodes. The origin was found by PET-CT and later confirmed by a biopsy.

Mentions: PET may also be of help in searching for the index tumour in patients presented with lymph node metastases of squamous cell carcinoma from unknown primary to the neck.51 Although detection rate of primary tumour ranges from 24%–44% as reviewed by Strojan et al.52, PET-CT should be performed when no primary lesion is suggested after thorough physical examination, indirect laryngoscopy and CT/MRI (Figure 2).51


The role of PET-CT in radiotherapy planning of solid tumours.

Jelercic S, Rajer M - Radiol Oncol (2015)

PET-CT images of 51-year old male with metastatic squamous cell carcinoma of unknown origin in cervical lymph nodes. The origin was found by PET-CT and later confirmed by a biopsy.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4362600&req=5

f2-rado-49-01-01: PET-CT images of 51-year old male with metastatic squamous cell carcinoma of unknown origin in cervical lymph nodes. The origin was found by PET-CT and later confirmed by a biopsy.
Mentions: PET may also be of help in searching for the index tumour in patients presented with lymph node metastases of squamous cell carcinoma from unknown primary to the neck.51 Although detection rate of primary tumour ranges from 24%–44% as reviewed by Strojan et al.52, PET-CT should be performed when no primary lesion is suggested after thorough physical examination, indirect laryngoscopy and CT/MRI (Figure 2).51

Bottom Line: PET-CT is becoming more and more important in various aspects of oncology.Until recently it was used mainly as part of diagnostic procedures and for evaluation of treatment results.Standard anatomical imaging used to select and delineate RT target volumes can be enriched by the information on tumour biology gained by PET-CT.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiotherapy, Institute of Oncology Ljubljana, Ljubljana, Slovenia.

ABSTRACT

Background: PET-CT is becoming more and more important in various aspects of oncology. Until recently it was used mainly as part of diagnostic procedures and for evaluation of treatment results. With development of personalized radiotherapy, volumetric and radiobiological characteristics of individual tumour have become integrated in the multistep radiotherapy (RT) planning process. Standard anatomical imaging used to select and delineate RT target volumes can be enriched by the information on tumour biology gained by PET-CT. In this review we explore the current and possible future role of PET-CT in radiotherapy treatment planning. After general explanation, we assess its role in radiotherapy of those solid tumours for which PET-CT is being used most.

Conclusions: In the nearby future PET-CT will be an integral part of the most radiotherapy treatment planning procedures in an every-day clinical practice. Apart from a clear role in radiation planning of lung cancer, with forthcoming clinical trials, we will get more evidence of the optimal use of PET-CT in radiotherapy planning of other solid tumours.

No MeSH data available.


Related in: MedlinePlus