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A bio-catalytically driven Janus mesoporous silica cluster motor with magnetic guidance.

Ma X, Sanchez S - Chem. Commun. (Camb.) (2015)

Bottom Line: A bio-catalytic Janus motor based on the mesoporous silica cluster (JMSC) is fabricated.Chemically conjugated catalase triggers the decomposition of H2O2 to produce driving force by bubble propulsion, while a metallic (Ni) coating layer allows for magnetic guidance of the motor.The JMSC motor can act as a delivery vehicle with cargo loading inside its mesopores.

View Article: PubMed Central - PubMed

Affiliation: Max Planck Institute for Intelligent Systems, Heisenbergstraße 3, 70569 Stuttgart, Germany. sanchez@is.mpg.de.

ABSTRACT
A bio-catalytic Janus motor based on the mesoporous silica cluster (JMSC) is fabricated. Chemically conjugated catalase triggers the decomposition of H2O2 to produce driving force by bubble propulsion, while a metallic (Ni) coating layer allows for magnetic guidance of the motor. The JMSC motor can act as a delivery vehicle with cargo loading inside its mesopores.

No MeSH data available.


Related in: MedlinePlus

(a) Schematic illustration and (b) video snaps of bio-catalytic reaction driven motion of a catalase conjugated JMSC motor under magnetic guidance with 3 wt% H2O2 (scale bar = 200 μm).
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fig4: (a) Schematic illustration and (b) video snaps of bio-catalytic reaction driven motion of a catalase conjugated JMSC motor under magnetic guidance with 3 wt% H2O2 (scale bar = 200 μm).

Mentions: Then, an external magnetic field was applied by using a permanent magnet, illustrated in Fig. 4a. Under magnetic guidance, the movement direction can be readily changed by varying the orientation of the magnetic field, as the trajectory was shown in Fig. 4b by the red curve. The JMSC motor indicated by the black arrow effectively produced bubbles to provide the driving force for the motor. We also observed the motion of the JMSC by bubble propulsion with H2O2 concentration as low as 1.5 wt%. The lower limit of H2O2 fuel concentration was found to be about 1 wt%, under which value bubble generation could barely be observed. Clearly, the JMSC motor was driven by the bubble propulsion mechanism. The bubble generation should be attributed to the rough surface with small cavities at the catalytic side of the JMSC motor. However, even under the same concentration of H2O2, the bubble generation rate, bubble size and speed of the motors varied a lot (Videos S3 and S4, ESI†), which can be explained by the non-uniform size and irregular shape of the JMSC motors given by uncontrolled aggregation of MSNPs during the synthesis.


A bio-catalytically driven Janus mesoporous silica cluster motor with magnetic guidance.

Ma X, Sanchez S - Chem. Commun. (Camb.) (2015)

(a) Schematic illustration and (b) video snaps of bio-catalytic reaction driven motion of a catalase conjugated JMSC motor under magnetic guidance with 3 wt% H2O2 (scale bar = 200 μm).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4362447&req=5

fig4: (a) Schematic illustration and (b) video snaps of bio-catalytic reaction driven motion of a catalase conjugated JMSC motor under magnetic guidance with 3 wt% H2O2 (scale bar = 200 μm).
Mentions: Then, an external magnetic field was applied by using a permanent magnet, illustrated in Fig. 4a. Under magnetic guidance, the movement direction can be readily changed by varying the orientation of the magnetic field, as the trajectory was shown in Fig. 4b by the red curve. The JMSC motor indicated by the black arrow effectively produced bubbles to provide the driving force for the motor. We also observed the motion of the JMSC by bubble propulsion with H2O2 concentration as low as 1.5 wt%. The lower limit of H2O2 fuel concentration was found to be about 1 wt%, under which value bubble generation could barely be observed. Clearly, the JMSC motor was driven by the bubble propulsion mechanism. The bubble generation should be attributed to the rough surface with small cavities at the catalytic side of the JMSC motor. However, even under the same concentration of H2O2, the bubble generation rate, bubble size and speed of the motors varied a lot (Videos S3 and S4, ESI†), which can be explained by the non-uniform size and irregular shape of the JMSC motors given by uncontrolled aggregation of MSNPs during the synthesis.

Bottom Line: A bio-catalytic Janus motor based on the mesoporous silica cluster (JMSC) is fabricated.Chemically conjugated catalase triggers the decomposition of H2O2 to produce driving force by bubble propulsion, while a metallic (Ni) coating layer allows for magnetic guidance of the motor.The JMSC motor can act as a delivery vehicle with cargo loading inside its mesopores.

View Article: PubMed Central - PubMed

Affiliation: Max Planck Institute for Intelligent Systems, Heisenbergstraße 3, 70569 Stuttgart, Germany. sanchez@is.mpg.de.

ABSTRACT
A bio-catalytic Janus motor based on the mesoporous silica cluster (JMSC) is fabricated. Chemically conjugated catalase triggers the decomposition of H2O2 to produce driving force by bubble propulsion, while a metallic (Ni) coating layer allows for magnetic guidance of the motor. The JMSC motor can act as a delivery vehicle with cargo loading inside its mesopores.

No MeSH data available.


Related in: MedlinePlus