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Etiologic and epidemiologic pattern of urolithiasis in north iran;review of 10-year findings.

Mohammadjafari H, Barzin M, Salehifar E, Khademi Kord M, Aalaee A, Mohammadjafari R - Iran J Pediatr (2014)

Bottom Line: Nearly all (99%) stones lay in kidney., 35.1% had metabolic, 10% infective and 4.1% obstructive trends, 110 children had no definable etiology.Hypercalciuria (25.5%) hyperoxaluria (18.4%) and hypocitraturia (18.1%) were more frequent than uricosuria (8.5%) and cystinuria (3.1%) Metabolic derangement plays significant role in stone formation in our area.Patients should be carefully evaluated considering this point of view.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Cellular and Molecular Research Center, Faculty of Medicine.

ABSTRACT

Objective: To determine epidemiologic and metabolic characteristics of renal stone in the northern Iran.

Methods: We prospectively analyzed demographic, clinical and metabolic findings in children less than 16 years old with renal stone revealed by ultrasonography from September 2003 to May 2012. Evaluations included serum and urine measurement of main elements predisposing patients to stone formation. Findings : 271 children (160 males) aged 2 months to 16-years (mean 30 months) were evaluated. 91 (33.6%) had a positive family history, abdominal discomfort (18.8%), UTI (11.8%) and hematuria (11.4%) were main presenting features. 45 children were diagnosed accidentally without any specific compliant. Nearly all (99%) stones lay in kidney., 35.1% had metabolic, 10% infective and 4.1% obstructive trends, 110 children had no definable etiology. Hypercalciuria (25.5%) hyperoxaluria (18.4%) and hypocitraturia (18.1%) were more frequent than uricosuria (8.5%) and cystinuria (3.1%)

Conclusion: Metabolic derangement plays significant role in stone formation in our area. Patients should be carefully evaluated considering this point of view.

No MeSH data available.


Related in: MedlinePlus

Location of stones
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Figure 1: Location of stones

Mentions: We studied 271 patients 2 mo to 16 years (mean 30 months) of age. One hundred and eleven were females, and the male to female ratio was 1.44. Patients were followed at least 6 (in average 22.3) months. Abdominal pain, infection and hematuria were the leading presenting features but many patients were diagnosed incidentally (Table 2). 91 (33.6%) patients had a positive family history of urolithiasis, most commonly (9.6%) giving a history of stone in father. The stone size ranged from 2 to 17 mm with average size of 4.8±2.7 mm. Most of stones (268, 99%) lay in kidneys (Fig 1).


Etiologic and epidemiologic pattern of urolithiasis in north iran;review of 10-year findings.

Mohammadjafari H, Barzin M, Salehifar E, Khademi Kord M, Aalaee A, Mohammadjafari R - Iran J Pediatr (2014)

Location of stones
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4359607&req=5

Figure 1: Location of stones
Mentions: We studied 271 patients 2 mo to 16 years (mean 30 months) of age. One hundred and eleven were females, and the male to female ratio was 1.44. Patients were followed at least 6 (in average 22.3) months. Abdominal pain, infection and hematuria were the leading presenting features but many patients were diagnosed incidentally (Table 2). 91 (33.6%) patients had a positive family history of urolithiasis, most commonly (9.6%) giving a history of stone in father. The stone size ranged from 2 to 17 mm with average size of 4.8±2.7 mm. Most of stones (268, 99%) lay in kidneys (Fig 1).

Bottom Line: Nearly all (99%) stones lay in kidney., 35.1% had metabolic, 10% infective and 4.1% obstructive trends, 110 children had no definable etiology.Hypercalciuria (25.5%) hyperoxaluria (18.4%) and hypocitraturia (18.1%) were more frequent than uricosuria (8.5%) and cystinuria (3.1%) Metabolic derangement plays significant role in stone formation in our area.Patients should be carefully evaluated considering this point of view.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Cellular and Molecular Research Center, Faculty of Medicine.

ABSTRACT

Objective: To determine epidemiologic and metabolic characteristics of renal stone in the northern Iran.

Methods: We prospectively analyzed demographic, clinical and metabolic findings in children less than 16 years old with renal stone revealed by ultrasonography from September 2003 to May 2012. Evaluations included serum and urine measurement of main elements predisposing patients to stone formation. Findings : 271 children (160 males) aged 2 months to 16-years (mean 30 months) were evaluated. 91 (33.6%) had a positive family history, abdominal discomfort (18.8%), UTI (11.8%) and hematuria (11.4%) were main presenting features. 45 children were diagnosed accidentally without any specific compliant. Nearly all (99%) stones lay in kidney., 35.1% had metabolic, 10% infective and 4.1% obstructive trends, 110 children had no definable etiology. Hypercalciuria (25.5%) hyperoxaluria (18.4%) and hypocitraturia (18.1%) were more frequent than uricosuria (8.5%) and cystinuria (3.1%)

Conclusion: Metabolic derangement plays significant role in stone formation in our area. Patients should be carefully evaluated considering this point of view.

No MeSH data available.


Related in: MedlinePlus