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Primitive neuroectodermal tumor in the spinal canal: A case report.

Meng XT, He SS - Oncol Lett (2015)

Bottom Line: The current study reports a case of PNET in a 60-year-old female, which presented clinically as an intraspinal tumor, causing symptoms of lower back pain, numbness and pain in the right lower extremity.Following primary therapy, the symptoms of spinal cord compression were relieved.After a further four months, the tumors recurred and the patient succumbed to the disease.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopaedics, Shanghai Tenth People's Hospital Affiliated to Tongji University, Shanghai 200072, P.R. China.

ABSTRACT

Primitive neuroectodermal tumors (PNETs) are rare tumors of uncertain histogenesis that occur predominantly in children and young adults. The current study reports a case of PNET in a 60-year-old female, which presented clinically as an intraspinal tumor, causing symptoms of lower back pain, numbness and pain in the right lower extremity. The patient underwent tumorectomy. Following primary therapy, the symptoms of spinal cord compression were relieved. The patient underwent several courses of radiotherapy following surgery but refused to continue with chemotherapy. After a further four months, the tumors recurred and the patient succumbed to the disease.

No MeSH data available.


Related in: MedlinePlus

Contrast enhanced magnetic resonance imaging of the lumbar spine revealed (A) a 4.9×2.1×1.8 cm homogeneously enhanced and (B) ill-defined mass from vertebrae L2–L3.
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f1-ol-09-04-1934: Contrast enhanced magnetic resonance imaging of the lumbar spine revealed (A) a 4.9×2.1×1.8 cm homogeneously enhanced and (B) ill-defined mass from vertebrae L2–L3.

Mentions: A 60-year-old female was admitted to Shanghai Tenth People’s Hospital Affiliated to Tongji University (Shanghai, China) due to a one-year history of increasing lower back pain, worsening numbness and pain on the back of the right thigh. The patient did not smoke or consume alcohol, and was suffering from diabetes, which was managed by a controlled diet. Initially, the patient’s blood pressure was 130/80 mmHg (normal range, 100–130/60–90 mmHg), with a regular pulse of 80 beats/min (normal range, 60–100 beats/min) and a respiratory rate of 18 breaths/min (normal range, 20–40 breaths/min). The patient was afebrile. On physical examination, hypoesthesia was detected on the back of the thigh and the knee jerk reflex was found to be reduced. In the straight leg raising test an angle of 30° was achieved. The results of all laboratory tests, including complete blood count, renal, bone, hepatic, and coagulation profiles, lactate dehydrogenase, carcinoembryonic antigen, α-fetoprotein, carbohydrate antigen (CA) 19-9 and CA12-5 levels, were normal. Computed tomography (CT) imaging of the lumbar spine revealed a 4.9×2.1×1.8 cm mass with ill-defined margins from the L2–L3 vertebrae (Fig. 1). The lesion was isointense on the T1-weighted image and iso- to hyperintense on the T2-weighted image. Abdominal and pelvic CT imaging and chest X-ray did not reveal any lesions. No evidence of ascites, or retroperitoneal or mesenteric lymphatic metastases was observed.


Primitive neuroectodermal tumor in the spinal canal: A case report.

Meng XT, He SS - Oncol Lett (2015)

Contrast enhanced magnetic resonance imaging of the lumbar spine revealed (A) a 4.9×2.1×1.8 cm homogeneously enhanced and (B) ill-defined mass from vertebrae L2–L3.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4356409&req=5

f1-ol-09-04-1934: Contrast enhanced magnetic resonance imaging of the lumbar spine revealed (A) a 4.9×2.1×1.8 cm homogeneously enhanced and (B) ill-defined mass from vertebrae L2–L3.
Mentions: A 60-year-old female was admitted to Shanghai Tenth People’s Hospital Affiliated to Tongji University (Shanghai, China) due to a one-year history of increasing lower back pain, worsening numbness and pain on the back of the right thigh. The patient did not smoke or consume alcohol, and was suffering from diabetes, which was managed by a controlled diet. Initially, the patient’s blood pressure was 130/80 mmHg (normal range, 100–130/60–90 mmHg), with a regular pulse of 80 beats/min (normal range, 60–100 beats/min) and a respiratory rate of 18 breaths/min (normal range, 20–40 breaths/min). The patient was afebrile. On physical examination, hypoesthesia was detected on the back of the thigh and the knee jerk reflex was found to be reduced. In the straight leg raising test an angle of 30° was achieved. The results of all laboratory tests, including complete blood count, renal, bone, hepatic, and coagulation profiles, lactate dehydrogenase, carcinoembryonic antigen, α-fetoprotein, carbohydrate antigen (CA) 19-9 and CA12-5 levels, were normal. Computed tomography (CT) imaging of the lumbar spine revealed a 4.9×2.1×1.8 cm mass with ill-defined margins from the L2–L3 vertebrae (Fig. 1). The lesion was isointense on the T1-weighted image and iso- to hyperintense on the T2-weighted image. Abdominal and pelvic CT imaging and chest X-ray did not reveal any lesions. No evidence of ascites, or retroperitoneal or mesenteric lymphatic metastases was observed.

Bottom Line: The current study reports a case of PNET in a 60-year-old female, which presented clinically as an intraspinal tumor, causing symptoms of lower back pain, numbness and pain in the right lower extremity.Following primary therapy, the symptoms of spinal cord compression were relieved.After a further four months, the tumors recurred and the patient succumbed to the disease.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopaedics, Shanghai Tenth People's Hospital Affiliated to Tongji University, Shanghai 200072, P.R. China.

ABSTRACT

Primitive neuroectodermal tumors (PNETs) are rare tumors of uncertain histogenesis that occur predominantly in children and young adults. The current study reports a case of PNET in a 60-year-old female, which presented clinically as an intraspinal tumor, causing symptoms of lower back pain, numbness and pain in the right lower extremity. The patient underwent tumorectomy. Following primary therapy, the symptoms of spinal cord compression were relieved. The patient underwent several courses of radiotherapy following surgery but refused to continue with chemotherapy. After a further four months, the tumors recurred and the patient succumbed to the disease.

No MeSH data available.


Related in: MedlinePlus