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Rescue therapy using an endobronchial valve and digital air leak monitoring in Invasive Pulmonary Aspergillosis.

Tsim S, Paton L, Nicholson F, Blyth KG - Respir Med Case Rep (2014)

Bottom Line: In this case report, we describe the utilisation of two recently developed technologies for the successful management of a persistent air leak (PAL) in a critically ill patient in whom cardiothoracic surgical intervention was not possible.We report the case of a young leukaemic woman with a PAL complicating Invasive Pulmonary Aspergillosis (IPA), who was effectively managed using an Endobronchial Valve, supplemented by objective, digital air leak data provided by a Thopaz(®) device (Medela, Switzerland).

View Article: PubMed Central - PubMed

Affiliation: Department of Respiratory Medicine, Southern General Hospital, Glasgow G51 4TF, United Kingdom.

ABSTRACT
In this case report, we describe the utilisation of two recently developed technologies for the successful management of a persistent air leak (PAL) in a critically ill patient in whom cardiothoracic surgical intervention was not possible. We report the case of a young leukaemic woman with a PAL complicating Invasive Pulmonary Aspergillosis (IPA), who was effectively managed using an Endobronchial Valve, supplemented by objective, digital air leak data provided by a Thopaz(®) device (Medela, Switzerland).

No MeSH data available.


Related in: MedlinePlus

A single axial image from a Thoracic Computed Tomography (CT) scan acquired on Day 110 in a leukaemic patient with Invasive Pulmonary Aspergillosis (IPA). A 4 mm endobronchial valve (Zephyr®, Pulmonx Inc. Neuchatel, Switzerland) is demonstrated within the lingular segmental bronchus proximal to an alveolar-pleural fistula caused by rupture of a fungal mass lesion. There has been a significant improvement in the previously demonstrated left-sided pneumothorax.
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fig3: A single axial image from a Thoracic Computed Tomography (CT) scan acquired on Day 110 in a leukaemic patient with Invasive Pulmonary Aspergillosis (IPA). A 4 mm endobronchial valve (Zephyr®, Pulmonx Inc. Neuchatel, Switzerland) is demonstrated within the lingular segmental bronchus proximal to an alveolar-pleural fistula caused by rupture of a fungal mass lesion. There has been a significant improvement in the previously demonstrated left-sided pneumothorax.

Mentions: Repeat CT imaging 2 weeks later demonstrated satisfactory positioning of the EBV and significant lung re-expansion (see Fig. 3). The remaining 12F ICD was removed 2 weeks later, following a 48-h period during which no measurable air leak had been detected on Thopaz®. The patient expectorated the EBV 3 weeks later without any adverse effect and was eventually discharged home following a 5-month admission. Prolonged antifungal therapy and continuing IV Arsenic and ATRA are planned. Her most recent bone marrow aspirate demonstrates continued molecular remission and she has been referred for allogeneic HSCT.


Rescue therapy using an endobronchial valve and digital air leak monitoring in Invasive Pulmonary Aspergillosis.

Tsim S, Paton L, Nicholson F, Blyth KG - Respir Med Case Rep (2014)

A single axial image from a Thoracic Computed Tomography (CT) scan acquired on Day 110 in a leukaemic patient with Invasive Pulmonary Aspergillosis (IPA). A 4 mm endobronchial valve (Zephyr®, Pulmonx Inc. Neuchatel, Switzerland) is demonstrated within the lingular segmental bronchus proximal to an alveolar-pleural fistula caused by rupture of a fungal mass lesion. There has been a significant improvement in the previously demonstrated left-sided pneumothorax.
© Copyright Policy - CC BY-NC-SA
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4356032&req=5

fig3: A single axial image from a Thoracic Computed Tomography (CT) scan acquired on Day 110 in a leukaemic patient with Invasive Pulmonary Aspergillosis (IPA). A 4 mm endobronchial valve (Zephyr®, Pulmonx Inc. Neuchatel, Switzerland) is demonstrated within the lingular segmental bronchus proximal to an alveolar-pleural fistula caused by rupture of a fungal mass lesion. There has been a significant improvement in the previously demonstrated left-sided pneumothorax.
Mentions: Repeat CT imaging 2 weeks later demonstrated satisfactory positioning of the EBV and significant lung re-expansion (see Fig. 3). The remaining 12F ICD was removed 2 weeks later, following a 48-h period during which no measurable air leak had been detected on Thopaz®. The patient expectorated the EBV 3 weeks later without any adverse effect and was eventually discharged home following a 5-month admission. Prolonged antifungal therapy and continuing IV Arsenic and ATRA are planned. Her most recent bone marrow aspirate demonstrates continued molecular remission and she has been referred for allogeneic HSCT.

Bottom Line: In this case report, we describe the utilisation of two recently developed technologies for the successful management of a persistent air leak (PAL) in a critically ill patient in whom cardiothoracic surgical intervention was not possible.We report the case of a young leukaemic woman with a PAL complicating Invasive Pulmonary Aspergillosis (IPA), who was effectively managed using an Endobronchial Valve, supplemented by objective, digital air leak data provided by a Thopaz(®) device (Medela, Switzerland).

View Article: PubMed Central - PubMed

Affiliation: Department of Respiratory Medicine, Southern General Hospital, Glasgow G51 4TF, United Kingdom.

ABSTRACT
In this case report, we describe the utilisation of two recently developed technologies for the successful management of a persistent air leak (PAL) in a critically ill patient in whom cardiothoracic surgical intervention was not possible. We report the case of a young leukaemic woman with a PAL complicating Invasive Pulmonary Aspergillosis (IPA), who was effectively managed using an Endobronchial Valve, supplemented by objective, digital air leak data provided by a Thopaz(®) device (Medela, Switzerland).

No MeSH data available.


Related in: MedlinePlus