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Factors associated with untreated diabetes: analysis of data from 20,496 participants in the Japanese National Health and Nutrition Survey.

Goto M, Goto A, Ikeda N, Noda H, Shibuya K, Noda M - PLoS ONE (2015)

Bottom Line: Individuals aged 20 years and older were included in the analysis.We conducted a multinomial logistic regression analysis to determine factors associated with untreated diabetes relative to non-diabetic individuals.Participants with untreated diabetes were significantly more likely than non-diabetic participants to be male, older, and currently smoking, have lower HDL cholesterol levels and higher BMI, non-HDL cholesterol levels, and systolic blood pressure.

View Article: PubMed Central - PubMed

Affiliation: Department of Diabetes Research, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo, Japan.

ABSTRACT

Objective: We aimed to examine factors associated with untreated diabetes in a nationally representative sample of the Japanese population.

Research design and methods: We pooled data from the Japanese National Health and Nutrition Survey from 2005 to 2009 (n = 20,496). Individuals aged 20 years and older were included in the analysis. We classified participants as having diabetes if they had HbA1c levels ≥6.5% (≥48 mmol/mol). People with diabetes who self-reported that they were not currently receiving diabetic treatment were considered to be untreated. We conducted a multinomial logistic regression analysis to determine factors associated with untreated diabetes relative to non-diabetic individuals.

Results: Of 20,496 participants who were included in the analysis, untreated diabetes was present in 748 (3.6%). Among participants with untreated diabetes, 48.3% were previously diagnosed with diabetes, and 46.5% had HbA1c levels ≥7.0% (≥53 mmol/mol). Participants with untreated diabetes were significantly more likely than non-diabetic participants to be male, older, and currently smoking, have lower HDL cholesterol levels and higher BMI, non-HDL cholesterol levels, and systolic blood pressure.

Conclusions: A substantial proportion of people in Japan with untreated diabetes have poor glycemic control. Targeting relevant factors for untreated diabetes in screening programs may be effective to enhance the treatment and control of diabetes.

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Related in: MedlinePlus

Distribution of HbA1c values among people with untreated diabetes (n = 748).Abbreviations: HbA1c, hemoglobin A1c.
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pone.0118749.g002: Distribution of HbA1c values among people with untreated diabetes (n = 748).Abbreviations: HbA1c, hemoglobin A1c.

Mentions: Out of 20,496 participants included in this study, 748 (3.6%) had untreated diabetes and 1,213 (5.9%) had treated diabetes (Fig. 1). Compared to people without diabetes, people with untreated diabetes had a significantly larger proportion of men, had significantly higher age, HbA1c levels, BMI, total and non-HDL cholesterol levels, triglyceride levels, and blood pressure, had significantly lower HDL cholesterol levels, and reported significantly higher rates of exercise habits and past and current smoking (Table 1). Among the 748 people with untreated diabetes, 361 (48.3%) were previously diagnosed with diabetes, and 348 (46.5%) had HbA1c levels ≥7.0% [≥53 mmol/mol] (Fig. 2).


Factors associated with untreated diabetes: analysis of data from 20,496 participants in the Japanese National Health and Nutrition Survey.

Goto M, Goto A, Ikeda N, Noda H, Shibuya K, Noda M - PLoS ONE (2015)

Distribution of HbA1c values among people with untreated diabetes (n = 748).Abbreviations: HbA1c, hemoglobin A1c.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4355906&req=5

pone.0118749.g002: Distribution of HbA1c values among people with untreated diabetes (n = 748).Abbreviations: HbA1c, hemoglobin A1c.
Mentions: Out of 20,496 participants included in this study, 748 (3.6%) had untreated diabetes and 1,213 (5.9%) had treated diabetes (Fig. 1). Compared to people without diabetes, people with untreated diabetes had a significantly larger proportion of men, had significantly higher age, HbA1c levels, BMI, total and non-HDL cholesterol levels, triglyceride levels, and blood pressure, had significantly lower HDL cholesterol levels, and reported significantly higher rates of exercise habits and past and current smoking (Table 1). Among the 748 people with untreated diabetes, 361 (48.3%) were previously diagnosed with diabetes, and 348 (46.5%) had HbA1c levels ≥7.0% [≥53 mmol/mol] (Fig. 2).

Bottom Line: Individuals aged 20 years and older were included in the analysis.We conducted a multinomial logistic regression analysis to determine factors associated with untreated diabetes relative to non-diabetic individuals.Participants with untreated diabetes were significantly more likely than non-diabetic participants to be male, older, and currently smoking, have lower HDL cholesterol levels and higher BMI, non-HDL cholesterol levels, and systolic blood pressure.

View Article: PubMed Central - PubMed

Affiliation: Department of Diabetes Research, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo, Japan.

ABSTRACT

Objective: We aimed to examine factors associated with untreated diabetes in a nationally representative sample of the Japanese population.

Research design and methods: We pooled data from the Japanese National Health and Nutrition Survey from 2005 to 2009 (n = 20,496). Individuals aged 20 years and older were included in the analysis. We classified participants as having diabetes if they had HbA1c levels ≥6.5% (≥48 mmol/mol). People with diabetes who self-reported that they were not currently receiving diabetic treatment were considered to be untreated. We conducted a multinomial logistic regression analysis to determine factors associated with untreated diabetes relative to non-diabetic individuals.

Results: Of 20,496 participants who were included in the analysis, untreated diabetes was present in 748 (3.6%). Among participants with untreated diabetes, 48.3% were previously diagnosed with diabetes, and 46.5% had HbA1c levels ≥7.0% (≥53 mmol/mol). Participants with untreated diabetes were significantly more likely than non-diabetic participants to be male, older, and currently smoking, have lower HDL cholesterol levels and higher BMI, non-HDL cholesterol levels, and systolic blood pressure.

Conclusions: A substantial proportion of people in Japan with untreated diabetes have poor glycemic control. Targeting relevant factors for untreated diabetes in screening programs may be effective to enhance the treatment and control of diabetes.

Show MeSH
Related in: MedlinePlus