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Microwave-assisted Extraction of Alantolactone and Isoalantolactone from Inula helenium.

Zhao YM, Wang J, Liu HB, Guo CY, Zhang WM - Indian J Pharm Sci (2015 Jan-Feb)

Bottom Line: Microwave-assisted extraction was used for the extraction of alantolactone and isoalantolactone from Inula helenium.The optimal extracting process of the alantolactone and isoalantolactone from the root of the Inula helenium was 1 g plant sample (sifted through 140 mesh) mixed with 15 ml of 80% ethanol solution, microwave radiation 120 s at 50°.Under these optimal conditions, the yield of alantolactone and isoalantolactone was 31.83±2.08 mg/g and 21.25±1.37 mg/g, respectively.

View Article: PubMed Central - PubMed

Affiliation: Department of Pharmacy, Hebei North University, No.11 Zuanshi South Road, Zhangjiakou-075 000, China.

ABSTRACT
Microwave-assisted extraction was used for the extraction of alantolactone and isoalantolactone from Inula helenium. Effects of various experimental factors including ethanol concentration, particle size, microwave radiation time, the ratio of material to liquid and extraction temperature on yield of alantolactone and isoalantolactone were evaluated. The optimal extracting process of the alantolactone and isoalantolactone from the root of the Inula helenium was 1 g plant sample (sifted through 140 mesh) mixed with 15 ml of 80% ethanol solution, microwave radiation 120 s at 50°. Under these optimal conditions, the yield of alantolactone and isoalantolactone was 31.83±2.08 mg/g and 21.25±1.37 mg/g, respectively. Compared with heat reflux extraction, ultrasound-assisted extraction, microwave-assisted extraction was more efficient and timesaving for the extraction of alantolactone and isoalantolactone from Inula helenium.

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Related in: MedlinePlus

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Mentions: In order to achieve the maximum of alantolactone and isoalantolactone extraction efficiency, different durations of microwave radiation (30, 60, 120, 180, 240, 360 s) was experimented. Other experimental conditions were the ratio of material to solvent (80% ethanol) at 1:10, and the extraction temperature were 50°. The yield of alantolactone and isoalantolactone under different microwave radiation time was shown in fig. 3. The yield of alantolactone and isoalantolactone increased rapidly within 30 s, and come to its maximum on 120 s, then almost unchanged. Longer extraction time may have negative effects because of degeneration or conversion of products. Therefore, in the subsequent experiments, 120 s was chosen as the extraction time.


Microwave-assisted Extraction of Alantolactone and Isoalantolactone from Inula helenium.

Zhao YM, Wang J, Liu HB, Guo CY, Zhang WM - Indian J Pharm Sci (2015 Jan-Feb)

© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4355875&req=5

Mentions: In order to achieve the maximum of alantolactone and isoalantolactone extraction efficiency, different durations of microwave radiation (30, 60, 120, 180, 240, 360 s) was experimented. Other experimental conditions were the ratio of material to solvent (80% ethanol) at 1:10, and the extraction temperature were 50°. The yield of alantolactone and isoalantolactone under different microwave radiation time was shown in fig. 3. The yield of alantolactone and isoalantolactone increased rapidly within 30 s, and come to its maximum on 120 s, then almost unchanged. Longer extraction time may have negative effects because of degeneration or conversion of products. Therefore, in the subsequent experiments, 120 s was chosen as the extraction time.

Bottom Line: Microwave-assisted extraction was used for the extraction of alantolactone and isoalantolactone from Inula helenium.The optimal extracting process of the alantolactone and isoalantolactone from the root of the Inula helenium was 1 g plant sample (sifted through 140 mesh) mixed with 15 ml of 80% ethanol solution, microwave radiation 120 s at 50°.Under these optimal conditions, the yield of alantolactone and isoalantolactone was 31.83±2.08 mg/g and 21.25±1.37 mg/g, respectively.

View Article: PubMed Central - PubMed

Affiliation: Department of Pharmacy, Hebei North University, No.11 Zuanshi South Road, Zhangjiakou-075 000, China.

ABSTRACT
Microwave-assisted extraction was used for the extraction of alantolactone and isoalantolactone from Inula helenium. Effects of various experimental factors including ethanol concentration, particle size, microwave radiation time, the ratio of material to liquid and extraction temperature on yield of alantolactone and isoalantolactone were evaluated. The optimal extracting process of the alantolactone and isoalantolactone from the root of the Inula helenium was 1 g plant sample (sifted through 140 mesh) mixed with 15 ml of 80% ethanol solution, microwave radiation 120 s at 50°. Under these optimal conditions, the yield of alantolactone and isoalantolactone was 31.83±2.08 mg/g and 21.25±1.37 mg/g, respectively. Compared with heat reflux extraction, ultrasound-assisted extraction, microwave-assisted extraction was more efficient and timesaving for the extraction of alantolactone and isoalantolactone from Inula helenium.

No MeSH data available.


Related in: MedlinePlus