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A case of multicentric carcinoid in a patient with psoriatic spondyloarthropathy.

George N, Depala A, Al Sweedan L, Chakravarty K - Case Rep Rheumatol (2015)

Bottom Line: We describe the first case of a patient presenting with multicentric carcinoid occurring in the lung and subsequently in the rectum, with chronic psoriatic arthritis.Initial presentation of carcinoid syndrome in this patient was insidious and atypical with few symptoms, including shortness of breath and long standing abdominal bloating.The case we report describes a rare presentation of carcinoid syndrome in chronic psoriatic arthropathy.

View Article: PubMed Central - PubMed

Affiliation: North Central Thames Foundation School, London NW3 2P, UK.

ABSTRACT
We describe the first case of a patient presenting with multicentric carcinoid occurring in the lung and subsequently in the rectum, with chronic psoriatic arthritis. Although reports have been published regarding carcinoid syndrome occurring alongside rheumatoid arthritis, no reports have been made on such a case. Initial presentation of carcinoid syndrome in this patient was insidious and atypical with few symptoms, including shortness of breath and long standing abdominal bloating. Several years later a sudden change in bowel habit prompted a colonoscopy with biopsy that revealed a carcinoid rectal polyp. The case we report describes a rare presentation of carcinoid syndrome in chronic psoriatic arthropathy.

No MeSH data available.


Related in: MedlinePlus

(a) Chest X-ray showed a 2 cm round opacity (white arrow) over the lower end of the right hilum with an inferiorly extending band shadow. (b) Transverse section chest contrast-enhanced computed tomography confirmed a 26 mm by 23 mm irregularly round lesion (black arrow) located at the bifurcation of the posterior segmental division of the lower lobe bronchus. There is further extension posteroinferiorly of the irregular soft tissue (arrowhead) contiguous from the lesion towards the costophrenic angle and diaphragm with pleural thickening.
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Related In: Results  -  Collection


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fig1: (a) Chest X-ray showed a 2 cm round opacity (white arrow) over the lower end of the right hilum with an inferiorly extending band shadow. (b) Transverse section chest contrast-enhanced computed tomography confirmed a 26 mm by 23 mm irregularly round lesion (black arrow) located at the bifurcation of the posterior segmental division of the lower lobe bronchus. There is further extension posteroinferiorly of the irregular soft tissue (arrowhead) contiguous from the lesion towards the costophrenic angle and diaphragm with pleural thickening.

Mentions: We present a case of a 54-year-old Caucasian lady, who three months following the diagnosis of PsA, presented with persistent cough and worsening dyspnoea at her outpatient clinic appointment. On examination, the patient had reduced chest expansion on the right side and a dull percussion note at the right lower zone. There was no clubbing and no lymphadenopathy. Urgent chest X-rays showed a suspicious 2 cm lesion in the right lower zone. During this time, the patient was being worked up for specific disease-modifying antirheumatic drug (DMARD) therapy, which was halted due to the unusual chest symptoms and imaging abnormalities. CT-guided transthoracic biopsy confirmed a 26 × 23 mm soft tissue lesion located at the bifurcation of the lower lobe bronchus. No mediastinal lymphadenopathy was noted. Histological analysis of the biopsy tissue revealed a benign typical carcinoid tumour (Figure 1).


A case of multicentric carcinoid in a patient with psoriatic spondyloarthropathy.

George N, Depala A, Al Sweedan L, Chakravarty K - Case Rep Rheumatol (2015)

(a) Chest X-ray showed a 2 cm round opacity (white arrow) over the lower end of the right hilum with an inferiorly extending band shadow. (b) Transverse section chest contrast-enhanced computed tomography confirmed a 26 mm by 23 mm irregularly round lesion (black arrow) located at the bifurcation of the posterior segmental division of the lower lobe bronchus. There is further extension posteroinferiorly of the irregular soft tissue (arrowhead) contiguous from the lesion towards the costophrenic angle and diaphragm with pleural thickening.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4353421&req=5

fig1: (a) Chest X-ray showed a 2 cm round opacity (white arrow) over the lower end of the right hilum with an inferiorly extending band shadow. (b) Transverse section chest contrast-enhanced computed tomography confirmed a 26 mm by 23 mm irregularly round lesion (black arrow) located at the bifurcation of the posterior segmental division of the lower lobe bronchus. There is further extension posteroinferiorly of the irregular soft tissue (arrowhead) contiguous from the lesion towards the costophrenic angle and diaphragm with pleural thickening.
Mentions: We present a case of a 54-year-old Caucasian lady, who three months following the diagnosis of PsA, presented with persistent cough and worsening dyspnoea at her outpatient clinic appointment. On examination, the patient had reduced chest expansion on the right side and a dull percussion note at the right lower zone. There was no clubbing and no lymphadenopathy. Urgent chest X-rays showed a suspicious 2 cm lesion in the right lower zone. During this time, the patient was being worked up for specific disease-modifying antirheumatic drug (DMARD) therapy, which was halted due to the unusual chest symptoms and imaging abnormalities. CT-guided transthoracic biopsy confirmed a 26 × 23 mm soft tissue lesion located at the bifurcation of the lower lobe bronchus. No mediastinal lymphadenopathy was noted. Histological analysis of the biopsy tissue revealed a benign typical carcinoid tumour (Figure 1).

Bottom Line: We describe the first case of a patient presenting with multicentric carcinoid occurring in the lung and subsequently in the rectum, with chronic psoriatic arthritis.Initial presentation of carcinoid syndrome in this patient was insidious and atypical with few symptoms, including shortness of breath and long standing abdominal bloating.The case we report describes a rare presentation of carcinoid syndrome in chronic psoriatic arthropathy.

View Article: PubMed Central - PubMed

Affiliation: North Central Thames Foundation School, London NW3 2P, UK.

ABSTRACT
We describe the first case of a patient presenting with multicentric carcinoid occurring in the lung and subsequently in the rectum, with chronic psoriatic arthritis. Although reports have been published regarding carcinoid syndrome occurring alongside rheumatoid arthritis, no reports have been made on such a case. Initial presentation of carcinoid syndrome in this patient was insidious and atypical with few symptoms, including shortness of breath and long standing abdominal bloating. Several years later a sudden change in bowel habit prompted a colonoscopy with biopsy that revealed a carcinoid rectal polyp. The case we report describes a rare presentation of carcinoid syndrome in chronic psoriatic arthropathy.

No MeSH data available.


Related in: MedlinePlus