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Effects of acupressure on fatigue and depression in hepatocellular carcinoma patients treated with transcatheter arterial chemoembolization: a quasi-experimental study.

Lan SC, Lin YE, Chen SC, Lin YF, Wang YJ - Evid Based Complement Alternat Med (2015)

Bottom Line: A quasiexperimental study design was used.There were no differences between the groups on depression.Acupressure can improve fatigue in HCC patients during treatment with TACE but did not alleviate depression.

View Article: PubMed Central - PubMed

Affiliation: Department of Nursing, Chang Gung Medical Foundation, Chang Gung Memorial Hospital, Linkou District 33305, Taiwan.

ABSTRACT
This study was to examine the effects of acupressure on fatigue and depression in HCC patients undergoing TACE. A quasiexperimental study design was used. Patients were evaluated at five time points: before treatment (T1) and 2, 3, 4, and 5 days after treating TACE (T2, T3, T4, and T5). Fatigue and depression were assessed by a VAS fatigue scale and a VAS depression scale at each time point. TFRS and BDI were administered at T1 and T5. Patients' fatigue and depression were significantly higher at T5 than at T1 in two groups. Fatigue and depression increased in both the experimental and control groups' patients over the five days of hospitalization during which TACE and chemotherapy were administered. The experimental group had significantly less fatigue than the control group, with lower subscale scores on physical, psychosocial, daily, and overall fatigue. There were no differences between the groups on depression. At posttest, the experimental group experienced lower physical, psychosocial, daily, and overall fatigue than the control group. Acupressure can improve fatigue in HCC patients during treatment with TACE but did not alleviate depression. Discharge planning should include home care for management of fatigue and depression.

No MeSH data available.


Related in: MedlinePlus

The flowchart of recruiting and TACE protocol.
© Copyright Policy - open-access
Related In: Results  -  Collection


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fig1: The flowchart of recruiting and TACE protocol.

Mentions: Before the study was conducted, it was approved by the Institutional Review Board of the study hospital. Written informed consent was obtained from the participants before collecting data. Subjects were randomized to groups because all patients at Chang Gung Memorial Hospital were treated with the same TACE protocol. To prevent contamination the nonrandomized assignment was used in this study, data collection for the control group was arranged first, and the experimental group was collected later. The control group received standard care, and the experimental group received acupressure (Figure 1).


Effects of acupressure on fatigue and depression in hepatocellular carcinoma patients treated with transcatheter arterial chemoembolization: a quasi-experimental study.

Lan SC, Lin YE, Chen SC, Lin YF, Wang YJ - Evid Based Complement Alternat Med (2015)

The flowchart of recruiting and TACE protocol.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4353412&req=5

fig1: The flowchart of recruiting and TACE protocol.
Mentions: Before the study was conducted, it was approved by the Institutional Review Board of the study hospital. Written informed consent was obtained from the participants before collecting data. Subjects were randomized to groups because all patients at Chang Gung Memorial Hospital were treated with the same TACE protocol. To prevent contamination the nonrandomized assignment was used in this study, data collection for the control group was arranged first, and the experimental group was collected later. The control group received standard care, and the experimental group received acupressure (Figure 1).

Bottom Line: A quasiexperimental study design was used.There were no differences between the groups on depression.Acupressure can improve fatigue in HCC patients during treatment with TACE but did not alleviate depression.

View Article: PubMed Central - PubMed

Affiliation: Department of Nursing, Chang Gung Medical Foundation, Chang Gung Memorial Hospital, Linkou District 33305, Taiwan.

ABSTRACT
This study was to examine the effects of acupressure on fatigue and depression in HCC patients undergoing TACE. A quasiexperimental study design was used. Patients were evaluated at five time points: before treatment (T1) and 2, 3, 4, and 5 days after treating TACE (T2, T3, T4, and T5). Fatigue and depression were assessed by a VAS fatigue scale and a VAS depression scale at each time point. TFRS and BDI were administered at T1 and T5. Patients' fatigue and depression were significantly higher at T5 than at T1 in two groups. Fatigue and depression increased in both the experimental and control groups' patients over the five days of hospitalization during which TACE and chemotherapy were administered. The experimental group had significantly less fatigue than the control group, with lower subscale scores on physical, psychosocial, daily, and overall fatigue. There were no differences between the groups on depression. At posttest, the experimental group experienced lower physical, psychosocial, daily, and overall fatigue than the control group. Acupressure can improve fatigue in HCC patients during treatment with TACE but did not alleviate depression. Discharge planning should include home care for management of fatigue and depression.

No MeSH data available.


Related in: MedlinePlus