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Comparison of pap smear quality with anatomical spatula method and the common method (spatula-cytobrush): a single blind clinical trial.

Soleimani M, Abdali Kh, Khajehei M, Tabatabaee HR, Komar PV, Riaz Montazer N - Iran J Cancer Prev (2012)

Bottom Line: The most important factor in false negative result is inappropriate tool of sampling.Regarding infection and inflammatory reactions there was no statistically significant difference between two methods (p>0.05).Based on our findings in this study, results of sampling with anatomical spatula method were more acceptable and better than those with spatula-cytobrush sampling.

View Article: PubMed Central - PubMed

Affiliation: Dept. of Midwifery, Fatemeh College of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran.

ABSTRACT

Background: Cervical cancer is the third most common cancer in women in the world. Papanicolaou smear is known as a standard test for cervical cancer screening; however, the most important challenge is high rates of false negative results. The aim of this study was to compare the quality of smears obtained by anatomical spatula and spatula-cytobrush. The most important factor in false negative result is inappropriate tool of sampling.

Methods: One hundred married women participated in this single blind clinical trial. All participants were interviewed; two samples were obtained from every participant: one with spatula-cytobrush and another one with anatomical spatula. All slides were encoded and were assessed by two pathologists. Then, data were analyzed by means of kappa coefficient.

Results: Cell adequacy was 96.1 % in anatomical spatula method and 91.2 % in spatula-cytobrush method (p= 0.016). The rates for endocervical cells and metaplasia cells in anatomical spatula method were 70.6% and 24.5% respectively and these amounts were 69.6% and 24.5% respectively in the spatula-cytobrush method (p <0.001). No one reported any pain and the amount of bleeding was 38.2% in both methods (P>0.05). Regarding infection and inflammatory reactions there was no statistically significant difference between two methods (p>0.05).

Conclusion: Based on our findings in this study, results of sampling with anatomical spatula method were more acceptable and better than those with spatula-cytobrush sampling.

No MeSH data available.


Related in: MedlinePlus

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Mentions: Data analysis was carried out using SPSS version15 for Windows. We used descriptive statistics in order to summarize demographic data. The kappa was used to compare the results of the two sampling tools.


Comparison of pap smear quality with anatomical spatula method and the common method (spatula-cytobrush): a single blind clinical trial.

Soleimani M, Abdali Kh, Khajehei M, Tabatabaee HR, Komar PV, Riaz Montazer N - Iran J Cancer Prev (2012)

© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4352524&req=5

Mentions: Data analysis was carried out using SPSS version15 for Windows. We used descriptive statistics in order to summarize demographic data. The kappa was used to compare the results of the two sampling tools.

Bottom Line: The most important factor in false negative result is inappropriate tool of sampling.Regarding infection and inflammatory reactions there was no statistically significant difference between two methods (p>0.05).Based on our findings in this study, results of sampling with anatomical spatula method were more acceptable and better than those with spatula-cytobrush sampling.

View Article: PubMed Central - PubMed

Affiliation: Dept. of Midwifery, Fatemeh College of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran.

ABSTRACT

Background: Cervical cancer is the third most common cancer in women in the world. Papanicolaou smear is known as a standard test for cervical cancer screening; however, the most important challenge is high rates of false negative results. The aim of this study was to compare the quality of smears obtained by anatomical spatula and spatula-cytobrush. The most important factor in false negative result is inappropriate tool of sampling.

Methods: One hundred married women participated in this single blind clinical trial. All participants were interviewed; two samples were obtained from every participant: one with spatula-cytobrush and another one with anatomical spatula. All slides were encoded and were assessed by two pathologists. Then, data were analyzed by means of kappa coefficient.

Results: Cell adequacy was 96.1 % in anatomical spatula method and 91.2 % in spatula-cytobrush method (p= 0.016). The rates for endocervical cells and metaplasia cells in anatomical spatula method were 70.6% and 24.5% respectively and these amounts were 69.6% and 24.5% respectively in the spatula-cytobrush method (p <0.001). No one reported any pain and the amount of bleeding was 38.2% in both methods (P>0.05). Regarding infection and inflammatory reactions there was no statistically significant difference between two methods (p>0.05).

Conclusion: Based on our findings in this study, results of sampling with anatomical spatula method were more acceptable and better than those with spatula-cytobrush sampling.

No MeSH data available.


Related in: MedlinePlus