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Comparison of pap smear quality with anatomical spatula method and the common method (spatula-cytobrush): a single blind clinical trial.

Soleimani M, Abdali Kh, Khajehei M, Tabatabaee HR, Komar PV, Riaz Montazer N - Iran J Cancer Prev (2012)

Bottom Line: The most important factor in false negative result is inappropriate tool of sampling.Regarding infection and inflammatory reactions there was no statistically significant difference between two methods (p>0.05).Based on our findings in this study, results of sampling with anatomical spatula method were more acceptable and better than those with spatula-cytobrush sampling.

View Article: PubMed Central - PubMed

Affiliation: Dept. of Midwifery, Fatemeh College of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran.

ABSTRACT

Background: Cervical cancer is the third most common cancer in women in the world. Papanicolaou smear is known as a standard test for cervical cancer screening; however, the most important challenge is high rates of false negative results. The aim of this study was to compare the quality of smears obtained by anatomical spatula and spatula-cytobrush. The most important factor in false negative result is inappropriate tool of sampling.

Methods: One hundred married women participated in this single blind clinical trial. All participants were interviewed; two samples were obtained from every participant: one with spatula-cytobrush and another one with anatomical spatula. All slides were encoded and were assessed by two pathologists. Then, data were analyzed by means of kappa coefficient.

Results: Cell adequacy was 96.1 % in anatomical spatula method and 91.2 % in spatula-cytobrush method (p= 0.016). The rates for endocervical cells and metaplasia cells in anatomical spatula method were 70.6% and 24.5% respectively and these amounts were 69.6% and 24.5% respectively in the spatula-cytobrush method (p <0.001). No one reported any pain and the amount of bleeding was 38.2% in both methods (P>0.05). Regarding infection and inflammatory reactions there was no statistically significant difference between two methods (p>0.05).

Conclusion: Based on our findings in this study, results of sampling with anatomical spatula method were more acceptable and better than those with spatula-cytobrush sampling.

No MeSH data available.


Related in: MedlinePlus

Resolution of cells in sampling with anatomical spatula
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Related In: Results  -  Collection

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f2-IJCP-05-033: Resolution of cells in sampling with anatomical spatula

Mentions: Although slides which were prepared with anatomical spatula had a higher resolution, there was no significant difference between the slides in both methods which had the same quality and showed the same cells (Figure 2 and Figure 3).


Comparison of pap smear quality with anatomical spatula method and the common method (spatula-cytobrush): a single blind clinical trial.

Soleimani M, Abdali Kh, Khajehei M, Tabatabaee HR, Komar PV, Riaz Montazer N - Iran J Cancer Prev (2012)

Resolution of cells in sampling with anatomical spatula
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4352524&req=5

f2-IJCP-05-033: Resolution of cells in sampling with anatomical spatula
Mentions: Although slides which were prepared with anatomical spatula had a higher resolution, there was no significant difference between the slides in both methods which had the same quality and showed the same cells (Figure 2 and Figure 3).

Bottom Line: The most important factor in false negative result is inappropriate tool of sampling.Regarding infection and inflammatory reactions there was no statistically significant difference between two methods (p>0.05).Based on our findings in this study, results of sampling with anatomical spatula method were more acceptable and better than those with spatula-cytobrush sampling.

View Article: PubMed Central - PubMed

Affiliation: Dept. of Midwifery, Fatemeh College of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran.

ABSTRACT

Background: Cervical cancer is the third most common cancer in women in the world. Papanicolaou smear is known as a standard test for cervical cancer screening; however, the most important challenge is high rates of false negative results. The aim of this study was to compare the quality of smears obtained by anatomical spatula and spatula-cytobrush. The most important factor in false negative result is inappropriate tool of sampling.

Methods: One hundred married women participated in this single blind clinical trial. All participants were interviewed; two samples were obtained from every participant: one with spatula-cytobrush and another one with anatomical spatula. All slides were encoded and were assessed by two pathologists. Then, data were analyzed by means of kappa coefficient.

Results: Cell adequacy was 96.1 % in anatomical spatula method and 91.2 % in spatula-cytobrush method (p= 0.016). The rates for endocervical cells and metaplasia cells in anatomical spatula method were 70.6% and 24.5% respectively and these amounts were 69.6% and 24.5% respectively in the spatula-cytobrush method (p <0.001). No one reported any pain and the amount of bleeding was 38.2% in both methods (P>0.05). Regarding infection and inflammatory reactions there was no statistically significant difference between two methods (p>0.05).

Conclusion: Based on our findings in this study, results of sampling with anatomical spatula method were more acceptable and better than those with spatula-cytobrush sampling.

No MeSH data available.


Related in: MedlinePlus