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Comparison of pap smear quality with anatomical spatula method and the common method (spatula-cytobrush): a single blind clinical trial.

Soleimani M, Abdali Kh, Khajehei M, Tabatabaee HR, Komar PV, Riaz Montazer N - Iran J Cancer Prev (2012)

Bottom Line: The most important factor in false negative result is inappropriate tool of sampling.Regarding infection and inflammatory reactions there was no statistically significant difference between two methods (p>0.05).Based on our findings in this study, results of sampling with anatomical spatula method were more acceptable and better than those with spatula-cytobrush sampling.

View Article: PubMed Central - PubMed

Affiliation: Dept. of Midwifery, Fatemeh College of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran.

ABSTRACT

Background: Cervical cancer is the third most common cancer in women in the world. Papanicolaou smear is known as a standard test for cervical cancer screening; however, the most important challenge is high rates of false negative results. The aim of this study was to compare the quality of smears obtained by anatomical spatula and spatula-cytobrush. The most important factor in false negative result is inappropriate tool of sampling.

Methods: One hundred married women participated in this single blind clinical trial. All participants were interviewed; two samples were obtained from every participant: one with spatula-cytobrush and another one with anatomical spatula. All slides were encoded and were assessed by two pathologists. Then, data were analyzed by means of kappa coefficient.

Results: Cell adequacy was 96.1 % in anatomical spatula method and 91.2 % in spatula-cytobrush method (p= 0.016). The rates for endocervical cells and metaplasia cells in anatomical spatula method were 70.6% and 24.5% respectively and these amounts were 69.6% and 24.5% respectively in the spatula-cytobrush method (p <0.001). No one reported any pain and the amount of bleeding was 38.2% in both methods (P>0.05). Regarding infection and inflammatory reactions there was no statistically significant difference between two methods (p>0.05).

Conclusion: Based on our findings in this study, results of sampling with anatomical spatula method were more acceptable and better than those with spatula-cytobrush sampling.

No MeSH data available.


Related in: MedlinePlus

Sample taking and spreading on slide with anatomical spatula
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f1-IJCP-05-033: Sample taking and spreading on slide with anatomical spatula

Mentions: Anatomical spatula is a wooden piece with length of 220 mm and width of 5 mm. This spatula has a long narrow arm with a length of 1.7 cm for sampling from endocervix, a shoulder and a completely flat curve for exocervical sampling and because of its anatomic structure is more compatible with women cervix. The arm of the spatula is placed inside the canal whilst its shoulder is on 3 o’clock position in exocervix. With gentle pressure, the spatula should be rotated in a clockwise direction through 360 degrees. Once the cells are spread on the slide, they are parallel to the slide edges and the slide is immediately fixed in a distance about 30 cm (Figure1).


Comparison of pap smear quality with anatomical spatula method and the common method (spatula-cytobrush): a single blind clinical trial.

Soleimani M, Abdali Kh, Khajehei M, Tabatabaee HR, Komar PV, Riaz Montazer N - Iran J Cancer Prev (2012)

Sample taking and spreading on slide with anatomical spatula
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4352524&req=5

f1-IJCP-05-033: Sample taking and spreading on slide with anatomical spatula
Mentions: Anatomical spatula is a wooden piece with length of 220 mm and width of 5 mm. This spatula has a long narrow arm with a length of 1.7 cm for sampling from endocervix, a shoulder and a completely flat curve for exocervical sampling and because of its anatomic structure is more compatible with women cervix. The arm of the spatula is placed inside the canal whilst its shoulder is on 3 o’clock position in exocervix. With gentle pressure, the spatula should be rotated in a clockwise direction through 360 degrees. Once the cells are spread on the slide, they are parallel to the slide edges and the slide is immediately fixed in a distance about 30 cm (Figure1).

Bottom Line: The most important factor in false negative result is inappropriate tool of sampling.Regarding infection and inflammatory reactions there was no statistically significant difference between two methods (p>0.05).Based on our findings in this study, results of sampling with anatomical spatula method were more acceptable and better than those with spatula-cytobrush sampling.

View Article: PubMed Central - PubMed

Affiliation: Dept. of Midwifery, Fatemeh College of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran.

ABSTRACT

Background: Cervical cancer is the third most common cancer in women in the world. Papanicolaou smear is known as a standard test for cervical cancer screening; however, the most important challenge is high rates of false negative results. The aim of this study was to compare the quality of smears obtained by anatomical spatula and spatula-cytobrush. The most important factor in false negative result is inappropriate tool of sampling.

Methods: One hundred married women participated in this single blind clinical trial. All participants were interviewed; two samples were obtained from every participant: one with spatula-cytobrush and another one with anatomical spatula. All slides were encoded and were assessed by two pathologists. Then, data were analyzed by means of kappa coefficient.

Results: Cell adequacy was 96.1 % in anatomical spatula method and 91.2 % in spatula-cytobrush method (p= 0.016). The rates for endocervical cells and metaplasia cells in anatomical spatula method were 70.6% and 24.5% respectively and these amounts were 69.6% and 24.5% respectively in the spatula-cytobrush method (p <0.001). No one reported any pain and the amount of bleeding was 38.2% in both methods (P>0.05). Regarding infection and inflammatory reactions there was no statistically significant difference between two methods (p>0.05).

Conclusion: Based on our findings in this study, results of sampling with anatomical spatula method were more acceptable and better than those with spatula-cytobrush sampling.

No MeSH data available.


Related in: MedlinePlus