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Prevalence of human papillomavirus variants and genetic diversity in the L1 gene and long control region of HPV16, HPV31, and HPV58 found in North-East Brazil.

Gurgel AP, Chagas BS, do Amaral CM, Nascimento KC, Leal LR, Silva Neto Jda C, Cartaxo Muniz MT, de Freitas AC - Biomed Res Int (2015)

Bottom Line: This study showed the prevalence of human papillomavirus (HPV) variants as well as nucleotide changes within L1 gene and LCR of the HPV16, HPV31, and HPV58 found in cervical lesions of women from North-East Brazil.

View Article: PubMed Central - PubMed

Affiliation: Laboratory of Molecular Studies and Experimental Therapy (LEMTE), Department of Genetics, Federal University of Pernambuco, Avenida Professor Moraes Rego S/N, 50670-901 Recife, PE, Brazil.

ABSTRACT
This study showed the prevalence of human papillomavirus (HPV) variants as well as nucleotide changes within L1 gene and LCR of the HPV16, HPV31, and HPV58 found in cervical lesions of women from North-East Brazil.

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Related in: MedlinePlus

Neighbor joining phylogenetic tree of HPV31 variants based on 783 pb of LCR. Reference sequences are listed in Table 2. Three clusters were identified as lineages A, B, and C. Viral lineages analyzed in this study (KJ435060-KJ435067) are clustered into A and C branches. Only bootstrap values above 50% are represented in the branches.
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Related In: Results  -  Collection


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fig3: Neighbor joining phylogenetic tree of HPV31 variants based on 783 pb of LCR. Reference sequences are listed in Table 2. Three clusters were identified as lineages A, B, and C. Viral lineages analyzed in this study (KJ435060-KJ435067) are clustered into A and C branches. Only bootstrap values above 50% are represented in the branches.

Mentions: The phylogenetic analysis showed 62.5% of variants are clustered into A branches (n = 5) and 37.5% are clustered into C branches (n = 3) (Figure 3). However, there were no observed variants clustered into B branches.


Prevalence of human papillomavirus variants and genetic diversity in the L1 gene and long control region of HPV16, HPV31, and HPV58 found in North-East Brazil.

Gurgel AP, Chagas BS, do Amaral CM, Nascimento KC, Leal LR, Silva Neto Jda C, Cartaxo Muniz MT, de Freitas AC - Biomed Res Int (2015)

Neighbor joining phylogenetic tree of HPV31 variants based on 783 pb of LCR. Reference sequences are listed in Table 2. Three clusters were identified as lineages A, B, and C. Viral lineages analyzed in this study (KJ435060-KJ435067) are clustered into A and C branches. Only bootstrap values above 50% are represented in the branches.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4352477&req=5

fig3: Neighbor joining phylogenetic tree of HPV31 variants based on 783 pb of LCR. Reference sequences are listed in Table 2. Three clusters were identified as lineages A, B, and C. Viral lineages analyzed in this study (KJ435060-KJ435067) are clustered into A and C branches. Only bootstrap values above 50% are represented in the branches.
Mentions: The phylogenetic analysis showed 62.5% of variants are clustered into A branches (n = 5) and 37.5% are clustered into C branches (n = 3) (Figure 3). However, there were no observed variants clustered into B branches.

Bottom Line: This study showed the prevalence of human papillomavirus (HPV) variants as well as nucleotide changes within L1 gene and LCR of the HPV16, HPV31, and HPV58 found in cervical lesions of women from North-East Brazil.

View Article: PubMed Central - PubMed

Affiliation: Laboratory of Molecular Studies and Experimental Therapy (LEMTE), Department of Genetics, Federal University of Pernambuco, Avenida Professor Moraes Rego S/N, 50670-901 Recife, PE, Brazil.

ABSTRACT
This study showed the prevalence of human papillomavirus (HPV) variants as well as nucleotide changes within L1 gene and LCR of the HPV16, HPV31, and HPV58 found in cervical lesions of women from North-East Brazil.

Show MeSH
Related in: MedlinePlus