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Prevalence of human papillomavirus variants and genetic diversity in the L1 gene and long control region of HPV16, HPV31, and HPV58 found in North-East Brazil.

Gurgel AP, Chagas BS, do Amaral CM, Nascimento KC, Leal LR, Silva Neto Jda C, Cartaxo Muniz MT, de Freitas AC - Biomed Res Int (2015)

Bottom Line: This study showed the prevalence of human papillomavirus (HPV) variants as well as nucleotide changes within L1 gene and LCR of the HPV16, HPV31, and HPV58 found in cervical lesions of women from North-East Brazil.

View Article: PubMed Central - PubMed

Affiliation: Laboratory of Molecular Studies and Experimental Therapy (LEMTE), Department of Genetics, Federal University of Pernambuco, Avenida Professor Moraes Rego S/N, 50670-901 Recife, PE, Brazil.

ABSTRACT
This study showed the prevalence of human papillomavirus (HPV) variants as well as nucleotide changes within L1 gene and LCR of the HPV16, HPV31, and HPV58 found in cervical lesions of women from North-East Brazil.

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Related in: MedlinePlus

Neighbor joining phylogenetic tree of HPV16 variants based on 759 pb of LCR. Four clusters were identified as lineages A, B, C, and D. Reference sequences are listed in Table 2. Viral lineages analyzed in this study (KJ452220-452242) are clustered into A and D branches. Only bootstrap values above 50% are represented in the branches.
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Related In: Results  -  Collection


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fig2: Neighbor joining phylogenetic tree of HPV16 variants based on 759 pb of LCR. Four clusters were identified as lineages A, B, C, and D. Reference sequences are listed in Table 2. Viral lineages analyzed in this study (KJ452220-452242) are clustered into A and D branches. Only bootstrap values above 50% are represented in the branches.

Mentions: The phylogenetic analyses showed that 63.63% (14/22) samples belong to the A variant and 36.36% (8/22) samples belong to the D variant (Figure 2). No variants in the B or C variant were found in this study (Figure 2).


Prevalence of human papillomavirus variants and genetic diversity in the L1 gene and long control region of HPV16, HPV31, and HPV58 found in North-East Brazil.

Gurgel AP, Chagas BS, do Amaral CM, Nascimento KC, Leal LR, Silva Neto Jda C, Cartaxo Muniz MT, de Freitas AC - Biomed Res Int (2015)

Neighbor joining phylogenetic tree of HPV16 variants based on 759 pb of LCR. Four clusters were identified as lineages A, B, C, and D. Reference sequences are listed in Table 2. Viral lineages analyzed in this study (KJ452220-452242) are clustered into A and D branches. Only bootstrap values above 50% are represented in the branches.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4352477&req=5

fig2: Neighbor joining phylogenetic tree of HPV16 variants based on 759 pb of LCR. Four clusters were identified as lineages A, B, C, and D. Reference sequences are listed in Table 2. Viral lineages analyzed in this study (KJ452220-452242) are clustered into A and D branches. Only bootstrap values above 50% are represented in the branches.
Mentions: The phylogenetic analyses showed that 63.63% (14/22) samples belong to the A variant and 36.36% (8/22) samples belong to the D variant (Figure 2). No variants in the B or C variant were found in this study (Figure 2).

Bottom Line: This study showed the prevalence of human papillomavirus (HPV) variants as well as nucleotide changes within L1 gene and LCR of the HPV16, HPV31, and HPV58 found in cervical lesions of women from North-East Brazil.

View Article: PubMed Central - PubMed

Affiliation: Laboratory of Molecular Studies and Experimental Therapy (LEMTE), Department of Genetics, Federal University of Pernambuco, Avenida Professor Moraes Rego S/N, 50670-901 Recife, PE, Brazil.

ABSTRACT
This study showed the prevalence of human papillomavirus (HPV) variants as well as nucleotide changes within L1 gene and LCR of the HPV16, HPV31, and HPV58 found in cervical lesions of women from North-East Brazil.

Show MeSH
Related in: MedlinePlus