Limits...
Perianal median raphe cyst: a rare lesion with unusual histology and localization.

Ünal B, Başsorgun Cİ, Eren Karanis Mİ, Elpek GÖ - Case Rep Dermatol Med (2015)

Bottom Line: The cysts can occur at parameatus, glans penis, penile shaft, scrotum, or perineum.Perianal region is an extremely rare location for these lesions.Here we present a 50-year-old male patient who presented with a cystic, fluctuant lesion, located at 12 o'clock in perianal region.

View Article: PubMed Central - PubMed

Affiliation: School of Medicine, Department of Pathology, Akdeniz University, 07070 Antalya, Turkey.

ABSTRACT
Median raphe cysts present anywhere between the external urethral meatus and the anus. The cysts can occur at parameatus, glans penis, penile shaft, scrotum, or perineum. Perianal region is an extremely rare location for these lesions. Here we present a 50-year-old male patient who presented with a cystic, fluctuant lesion, located at 12 o'clock in perianal region. Microscopic examination revealed a cystic lesion with keratinized and nonkeratinized stratified squamous epithelium, pseudostratified ciliated epithelium, and scattered goblet cells. The final diagnosis of the lesion was median raphe cyst. Ciliated cells and perianal localization in median raphe cysts are extremely rare characteristics.

No MeSH data available.


Related in: MedlinePlus

(a) Pigmented macrophages under stratified squamous epithelium. (b) This pigmented area consisted of blue colored hemosiderin and brown colored melanin ((a) hematoxylin and eosin and (b) Prussian blue, magnifications (a) and (b) ×100).
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC4352436&req=5

fig4: (a) Pigmented macrophages under stratified squamous epithelium. (b) This pigmented area consisted of blue colored hemosiderin and brown colored melanin ((a) hematoxylin and eosin and (b) Prussian blue, magnifications (a) and (b) ×100).

Mentions: A 50-year-old male patient presented with a cystic, fluctuant lesion, located at 12 o'clock in perianal region. Any other pathology was not detected in perineal, scrotal, and perineal area. Surgical procedure was performed and cystic lesion was excised. Microscopic examination revealed a cystic lesion with a diameter of 37 mm and 3 mm wall thickness which was located in the dermis (Figure 1(a)). The epithelial lining of cyst consisted of keratinized and nonkeratinized stratified squamous epithelium (Figure 1(b)), pseudostratified ciliated epithelium (Figure 2), and scattered goblet cells (Figure 3(a)). Under the cyst epithelium, in some areas, hemosiderin laden macrophages, pigment of melanin, were seen. Immunohistochemical Melan-A and histochemical Prussian blue were performed for these areas (Figures 4(a) and 4(b)). Mucin secretion in goblet cells was shown by histochemical mucicarmine staining (Figure 3(b)). At 4 years of followup there was no evidence of recurrence.


Perianal median raphe cyst: a rare lesion with unusual histology and localization.

Ünal B, Başsorgun Cİ, Eren Karanis Mİ, Elpek GÖ - Case Rep Dermatol Med (2015)

(a) Pigmented macrophages under stratified squamous epithelium. (b) This pigmented area consisted of blue colored hemosiderin and brown colored melanin ((a) hematoxylin and eosin and (b) Prussian blue, magnifications (a) and (b) ×100).
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4352436&req=5

fig4: (a) Pigmented macrophages under stratified squamous epithelium. (b) This pigmented area consisted of blue colored hemosiderin and brown colored melanin ((a) hematoxylin and eosin and (b) Prussian blue, magnifications (a) and (b) ×100).
Mentions: A 50-year-old male patient presented with a cystic, fluctuant lesion, located at 12 o'clock in perianal region. Any other pathology was not detected in perineal, scrotal, and perineal area. Surgical procedure was performed and cystic lesion was excised. Microscopic examination revealed a cystic lesion with a diameter of 37 mm and 3 mm wall thickness which was located in the dermis (Figure 1(a)). The epithelial lining of cyst consisted of keratinized and nonkeratinized stratified squamous epithelium (Figure 1(b)), pseudostratified ciliated epithelium (Figure 2), and scattered goblet cells (Figure 3(a)). Under the cyst epithelium, in some areas, hemosiderin laden macrophages, pigment of melanin, were seen. Immunohistochemical Melan-A and histochemical Prussian blue were performed for these areas (Figures 4(a) and 4(b)). Mucin secretion in goblet cells was shown by histochemical mucicarmine staining (Figure 3(b)). At 4 years of followup there was no evidence of recurrence.

Bottom Line: The cysts can occur at parameatus, glans penis, penile shaft, scrotum, or perineum.Perianal region is an extremely rare location for these lesions.Here we present a 50-year-old male patient who presented with a cystic, fluctuant lesion, located at 12 o'clock in perianal region.

View Article: PubMed Central - PubMed

Affiliation: School of Medicine, Department of Pathology, Akdeniz University, 07070 Antalya, Turkey.

ABSTRACT
Median raphe cysts present anywhere between the external urethral meatus and the anus. The cysts can occur at parameatus, glans penis, penile shaft, scrotum, or perineum. Perianal region is an extremely rare location for these lesions. Here we present a 50-year-old male patient who presented with a cystic, fluctuant lesion, located at 12 o'clock in perianal region. Microscopic examination revealed a cystic lesion with keratinized and nonkeratinized stratified squamous epithelium, pseudostratified ciliated epithelium, and scattered goblet cells. The final diagnosis of the lesion was median raphe cyst. Ciliated cells and perianal localization in median raphe cysts are extremely rare characteristics.

No MeSH data available.


Related in: MedlinePlus