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A very rare case of primary meningococcal arthritis in an adult male.

Nihonyanagi S, Sunakawa K, Cui L, Masaki T, Wada T, Hoshiyama T, Nakamura M, Takayama Y, Kanoh Y, Ogawa A, Shichiri M, Hanaki H - Clin Case Rep (2014)

Bottom Line: We report here a very rare case of primary meningococcal arthritis of the knee joint without clinical features associated with meningococcemia, meningitis, or meningococcal complications.The patient suffered from diabetes mellitus and had experienced two episodes of joint trauma.Intravenous infusion of ampicillin/sulbactam for 18 consecutive days was successful.

View Article: PubMed Central - PubMed

Affiliation: Department of Medical Laboratory, Kitasato University Hospital 1-15-1 Kitasato, Sagamihara, Kanagawa, 252-0373, Japan ; Kitasato Institute for Life Sciences and Laboratory for Antimicrobial Agents, Kitasato University 1-15-1 Kitasato, Sagamihara, Kanagawa, 252-0373, Japan.

ABSTRACT
We report here a very rare case of primary meningococcal arthritis of the knee joint without clinical features associated with meningococcemia, meningitis, or meningococcal complications. The patient suffered from diabetes mellitus and had experienced two episodes of joint trauma. Intravenous infusion of ampicillin/sulbactam for 18 consecutive days was successful.

No MeSH data available.


Related in: MedlinePlus

Clinical findings, treatments, and laboratory data during hospitalization.
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fig01: Clinical findings, treatments, and laboratory data during hospitalization.

Mentions: Microscopic examination of the centrifuged and Gram-stained synovial fluid revealed Gram-negative diplococci. Therefore, he was first suspected of having purulent arthritis, so we immediately administered ampicillin/sulbactam (2:1, w/w ratio) intravenously at a dose of 1.5 g × 4 times per day, for 18 consecutive days. For the diabetes, insulin detemir was administered according to the regime shown in Fig.1. An electrolyte supplement was given as an intravenous infusion to treat the patient's dehydration. Magnetic resonance imaging (MRI) of the right knee joint taken on the day of admission revealed effusion of the synovial fluid, thickening of the inflamed synovium, and mild degenerative bone changes (Fig.2).


A very rare case of primary meningococcal arthritis in an adult male.

Nihonyanagi S, Sunakawa K, Cui L, Masaki T, Wada T, Hoshiyama T, Nakamura M, Takayama Y, Kanoh Y, Ogawa A, Shichiri M, Hanaki H - Clin Case Rep (2014)

Clinical findings, treatments, and laboratory data during hospitalization.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4352356&req=5

fig01: Clinical findings, treatments, and laboratory data during hospitalization.
Mentions: Microscopic examination of the centrifuged and Gram-stained synovial fluid revealed Gram-negative diplococci. Therefore, he was first suspected of having purulent arthritis, so we immediately administered ampicillin/sulbactam (2:1, w/w ratio) intravenously at a dose of 1.5 g × 4 times per day, for 18 consecutive days. For the diabetes, insulin detemir was administered according to the regime shown in Fig.1. An electrolyte supplement was given as an intravenous infusion to treat the patient's dehydration. Magnetic resonance imaging (MRI) of the right knee joint taken on the day of admission revealed effusion of the synovial fluid, thickening of the inflamed synovium, and mild degenerative bone changes (Fig.2).

Bottom Line: We report here a very rare case of primary meningococcal arthritis of the knee joint without clinical features associated with meningococcemia, meningitis, or meningococcal complications.The patient suffered from diabetes mellitus and had experienced two episodes of joint trauma.Intravenous infusion of ampicillin/sulbactam for 18 consecutive days was successful.

View Article: PubMed Central - PubMed

Affiliation: Department of Medical Laboratory, Kitasato University Hospital 1-15-1 Kitasato, Sagamihara, Kanagawa, 252-0373, Japan ; Kitasato Institute for Life Sciences and Laboratory for Antimicrobial Agents, Kitasato University 1-15-1 Kitasato, Sagamihara, Kanagawa, 252-0373, Japan.

ABSTRACT
We report here a very rare case of primary meningococcal arthritis of the knee joint without clinical features associated with meningococcemia, meningitis, or meningococcal complications. The patient suffered from diabetes mellitus and had experienced two episodes of joint trauma. Intravenous infusion of ampicillin/sulbactam for 18 consecutive days was successful.

No MeSH data available.


Related in: MedlinePlus