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Incidence of defibrillator shocks after elective generator exchange following uneventful first battery life.

Merchant FM, Jones P, Wehrenberg S, Lloyd MS, Saxon LA - J Am Heart Assoc (2014)

Bottom Line: Elective generator exchange (GE) has been associated with increased risk of infection and ICD lead failure.In this large cohort of ICD patients implanted across the United States, two thirds did not receive ICD shock therapy prior to GE.These data should support informed decision making for patients and physicians at the time of ICD generator end of service.

View Article: PubMed Central - PubMed

Affiliation: Cardiology Division, Emory University School of Medicine, Atlanta, GA (F.M.M., M.S.L.).

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Related in: MedlinePlus

Cumulative rate of ICD shocks following generator exchange in groups A and B. Cumulative rate and number at risk are specified beneath each time point. ICD indicates implantable cardioverter‐defibrillator.
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fig01: Cumulative rate of ICD shocks following generator exchange in groups A and B. Cumulative rate and number at risk are specified beneath each time point. ICD indicates implantable cardioverter‐defibrillator.

Mentions: During an average follow‐up of 1.9±1.2 years after GE, the percentage of patients with shocks and the risk of ICD shocks were lower in group A (9.9% versus 27.7%, HR 0.36, 95% CI 0.34 to 0.38, P<0.001). The cumulative rate of ICD shocks at 5 years after GE was 25.7% in group A and 51.1% in group B (Figure 1). As shown in Figure 1, the frequency of ICD shocks after GE in both groups was relatively constant, beginning within the first year after GE and without evidence of reaching a plateau by 5 years.


Incidence of defibrillator shocks after elective generator exchange following uneventful first battery life.

Merchant FM, Jones P, Wehrenberg S, Lloyd MS, Saxon LA - J Am Heart Assoc (2014)

Cumulative rate of ICD shocks following generator exchange in groups A and B. Cumulative rate and number at risk are specified beneath each time point. ICD indicates implantable cardioverter‐defibrillator.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4338723&req=5

fig01: Cumulative rate of ICD shocks following generator exchange in groups A and B. Cumulative rate and number at risk are specified beneath each time point. ICD indicates implantable cardioverter‐defibrillator.
Mentions: During an average follow‐up of 1.9±1.2 years after GE, the percentage of patients with shocks and the risk of ICD shocks were lower in group A (9.9% versus 27.7%, HR 0.36, 95% CI 0.34 to 0.38, P<0.001). The cumulative rate of ICD shocks at 5 years after GE was 25.7% in group A and 51.1% in group B (Figure 1). As shown in Figure 1, the frequency of ICD shocks after GE in both groups was relatively constant, beginning within the first year after GE and without evidence of reaching a plateau by 5 years.

Bottom Line: Elective generator exchange (GE) has been associated with increased risk of infection and ICD lead failure.In this large cohort of ICD patients implanted across the United States, two thirds did not receive ICD shock therapy prior to GE.These data should support informed decision making for patients and physicians at the time of ICD generator end of service.

View Article: PubMed Central - PubMed

Affiliation: Cardiology Division, Emory University School of Medicine, Atlanta, GA (F.M.M., M.S.L.).

Show MeSH
Related in: MedlinePlus