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Squamous cell carcinoma of the middle rectum: Report of a case and literature overview.

Scaringi S, Bisogni D, Messerini L, Bechi P - Int J Surg Case Rep (2014)

Bottom Line: Risk factors for SCC of the rectum are unknown and many hypotheses have been evocated.Because of its rarity, the interpretation of available information is clouded by a lack of uniformity in diagnosis and treatment.Treatment of SCC remains very challenging, and the acquisition of more consistent data is needed.

View Article: PubMed Central - PubMed

Affiliation: Second General Surgery, Department of Surgery and Translational Medicine, Careggi Teaching Hospital, Florence, Italy.

No MeSH data available.


Related in: MedlinePlus

Squamous epithelial cells in the context of glandular mucosa infiltrating the submucosa. The simple tubular glands show superficial hyperkeratinization. Evidence of extensive infiltration of lympho-monocytic cells in the submucosa (hematoxylin–eosin ×20).
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fig0015: Squamous epithelial cells in the context of glandular mucosa infiltrating the submucosa. The simple tubular glands show superficial hyperkeratinization. Evidence of extensive infiltration of lympho-monocytic cells in the submucosa (hematoxylin–eosin ×20).

Mentions: After multidisciplinary discussion neoadjuvant treatment was excluded because of the previous radiotherapy for prostate cancer. The patient was addressed to surgical treatment. A lower anterior resection with total mesorectal excision combined to the right ureteral resection was performed. Histology confirmed an atypical squamous cell rectal cancer, that was classificated pT3N1, and an inverted papilloma of the right ureter (Fig. 3). Post-operative outcome was uneventful. Patient died 4 months later for local recurrence and distant dissemination (nodal and pulmonary).


Squamous cell carcinoma of the middle rectum: Report of a case and literature overview.

Scaringi S, Bisogni D, Messerini L, Bechi P - Int J Surg Case Rep (2014)

Squamous epithelial cells in the context of glandular mucosa infiltrating the submucosa. The simple tubular glands show superficial hyperkeratinization. Evidence of extensive infiltration of lympho-monocytic cells in the submucosa (hematoxylin–eosin ×20).
© Copyright Policy - CC BY-NC-ND
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4336389&req=5

fig0015: Squamous epithelial cells in the context of glandular mucosa infiltrating the submucosa. The simple tubular glands show superficial hyperkeratinization. Evidence of extensive infiltration of lympho-monocytic cells in the submucosa (hematoxylin–eosin ×20).
Mentions: After multidisciplinary discussion neoadjuvant treatment was excluded because of the previous radiotherapy for prostate cancer. The patient was addressed to surgical treatment. A lower anterior resection with total mesorectal excision combined to the right ureteral resection was performed. Histology confirmed an atypical squamous cell rectal cancer, that was classificated pT3N1, and an inverted papilloma of the right ureter (Fig. 3). Post-operative outcome was uneventful. Patient died 4 months later for local recurrence and distant dissemination (nodal and pulmonary).

Bottom Line: Risk factors for SCC of the rectum are unknown and many hypotheses have been evocated.Because of its rarity, the interpretation of available information is clouded by a lack of uniformity in diagnosis and treatment.Treatment of SCC remains very challenging, and the acquisition of more consistent data is needed.

View Article: PubMed Central - PubMed

Affiliation: Second General Surgery, Department of Surgery and Translational Medicine, Careggi Teaching Hospital, Florence, Italy.

No MeSH data available.


Related in: MedlinePlus