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Realtime MR guided endomyocardial biopsy with an active visualization bioptome

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We performed realtime MR guided transcatheter endomyocardial biopsy using a novel active visualization MR conditional bioptome in swine... An active visualization MR conditional bioptome was designed and built for transcatheter endomyocardial biopsy... The bioptome was tested in a phantom and in vivo in swine to perform transcatheter right and left ventricular endomyocardial biopsy under realtime MR guidance... The bioptome shaft was actively visualized under realtime MR imaging... Using the curve of the sheath, it was possible to direct the bioptome to different locations with the ventricles and perform biopsy... Multiple biopsy samples were obtained to demonstrate cutting ability of the bioptome jaws (Figure 1B)... Future iterations of the device will include a deflection mechanism and additional active visualization of the jaws to confirm open/closed position... We have developed and tested in vivo an active visualization MR conditional endomyocardial bioptome... We have demonstrated clear visualization of the bioptome shaft and jaws under realtime MR guidance... In an animal experiment, the bioptome was steered to different locations with the ventricles and multiple biopsy samples were obtained.

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Mentions: The bioptome shaft was actively visualized under realtime MR imaging. The jaws appeared as a distinct signal void in the phantom and in vivo (arrow, Figure 1A). Device heating was negligible in a phantom. The bioptome was navigated to the right ventricular outflow tract and left ventricle through a standard 7Fr multipurpose curve biopsy sheath. Using the curve of the sheath, it was possible to direct the bioptome to different locations with the ventricles and perform biopsy. Multiple biopsy samples were obtained to demonstrate cutting ability of the bioptome jaws (Figure 1B). Future iterations of the device will include a deflection mechanism and additional active visualization of the jaws to confirm open/closed position.


Realtime MR guided endomyocardial biopsy with an active visualization bioptome
Figure 1
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4328989&req=5

Fig1: Figure 1
Mentions: The bioptome shaft was actively visualized under realtime MR imaging. The jaws appeared as a distinct signal void in the phantom and in vivo (arrow, Figure 1A). Device heating was negligible in a phantom. The bioptome was navigated to the right ventricular outflow tract and left ventricle through a standard 7Fr multipurpose curve biopsy sheath. Using the curve of the sheath, it was possible to direct the bioptome to different locations with the ventricles and perform biopsy. Multiple biopsy samples were obtained to demonstrate cutting ability of the bioptome jaws (Figure 1B). Future iterations of the device will include a deflection mechanism and additional active visualization of the jaws to confirm open/closed position.

View Article: PubMed Central

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

We performed realtime MR guided transcatheter endomyocardial biopsy using a novel active visualization MR conditional bioptome in swine... An active visualization MR conditional bioptome was designed and built for transcatheter endomyocardial biopsy... The bioptome was tested in a phantom and in vivo in swine to perform transcatheter right and left ventricular endomyocardial biopsy under realtime MR guidance... The bioptome shaft was actively visualized under realtime MR imaging... Using the curve of the sheath, it was possible to direct the bioptome to different locations with the ventricles and perform biopsy... Multiple biopsy samples were obtained to demonstrate cutting ability of the bioptome jaws (Figure 1B)... Future iterations of the device will include a deflection mechanism and additional active visualization of the jaws to confirm open/closed position... We have developed and tested in vivo an active visualization MR conditional endomyocardial bioptome... We have demonstrated clear visualization of the bioptome shaft and jaws under realtime MR guidance... In an animal experiment, the bioptome was steered to different locations with the ventricles and multiple biopsy samples were obtained.

No MeSH data available.