Limits...
Accuracy of self-navigated free-breathing isotropic 3D whole heart inversion recovery magnetic resonance for detection of myocardial infarction

View Article: PubMed Central - HTML

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Cardiac magnetic resonance (CMR) allows detection of myocardial scar after myocardial infarction... Patients after myocardial infarction detected by late gadolinium enhancement on standard 2D inversion recovery sequences (2D LGE) underwent a CMR exam with 3D-SNIR on a 1.5T clinical CMR scanner (Aera, Siemens, Germany)... TI (= 250-300ms) was assessed with a 2D radial scout scan prior to 3D-SNIR... A total of about 12'000 radial readouts were acquired for each 3D scan during free breathing with 100% respiratory efficiency. 3D LGE datasets were compared to standard 2D LGE for scar tissue detection with Osirix® software... Scar tissue was segmented on reconstructed slices on standard 2D and 3D-SNIR LGE and multiplied by slice thickness... Thirteen patients (5 females, age 58±10y) were included... Time between 2D LGE and 3D LGE was 59 ± 64 days. 3D-SNIR successfully corrected for respiratory motion in all acquisitions... All scars visualized by 2D LGE could be identified by 3D-SNIR (example see figure 1)... Bland Altman-analyses and correlations showed a good agreement of quantification of scar volume obtained by 3D-SNIR compared to standard 2D LGE: -6.3±4.1ml, linear regression: r=0.977, p<0.001 (figure 2). 3D scar volume was 24.3±15ml vs. 2D 30.6±17ml, p<0.001... Intraobserver variability was 0.3±4.9ml, r=0.985, p<0.001; interobserver 1.5±9.9ml, r=0.74, p=0.014... Detection of myocardial scar by 3D-SNIR is feasible and shows a good agreement with standard 2D LGE... The mean difference of -6.3ml might be explained by the higher spatial resolution of the 3D sequence.

No MeSH data available.


Related in: MedlinePlus

Correlation of volume of scar determined by 2D and 3D late gadolinium enhancement
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
getmorefigures.php?uid=PMC4328904&req=5

Figure 2: Correlation of volume of scar determined by 2D and 3D late gadolinium enhancement

Mentions: Thirteen patients (5 females, age 58±10y) were included. Time between 2D LGE and 3D LGE was 59 ± 64 days. 3D-SNIR successfully corrected for respiratory motion in all acquisitions. All scars visualized by 2D LGE could be identified by 3D-SNIR (example see figure 1). Bland Altman-analyses and correlations showed a good agreement of quantification of scar volume obtained by 3D-SNIR compared to standard 2D LGE: -6.3±4.1ml, linear regression: r=0.977, p<0.001 (figure 2). 3D scar volume was 24.3±15ml vs. 2D 30.6±17ml, p<0.001. Intraobserver variability was 0.3±4.9ml, r=0.985, p<0.001; interobserver 1.5±9.9ml, r=0.74, p=0.014.


Accuracy of self-navigated free-breathing isotropic 3D whole heart inversion recovery magnetic resonance for detection of myocardial infarction
Correlation of volume of scar determined by 2D and 3D late gadolinium enhancement
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4328904&req=5

Figure 2: Correlation of volume of scar determined by 2D and 3D late gadolinium enhancement
Mentions: Thirteen patients (5 females, age 58±10y) were included. Time between 2D LGE and 3D LGE was 59 ± 64 days. 3D-SNIR successfully corrected for respiratory motion in all acquisitions. All scars visualized by 2D LGE could be identified by 3D-SNIR (example see figure 1). Bland Altman-analyses and correlations showed a good agreement of quantification of scar volume obtained by 3D-SNIR compared to standard 2D LGE: -6.3±4.1ml, linear regression: r=0.977, p<0.001 (figure 2). 3D scar volume was 24.3±15ml vs. 2D 30.6±17ml, p<0.001. Intraobserver variability was 0.3±4.9ml, r=0.985, p<0.001; interobserver 1.5±9.9ml, r=0.74, p=0.014.

View Article: PubMed Central - HTML

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Cardiac magnetic resonance (CMR) allows detection of myocardial scar after myocardial infarction... Patients after myocardial infarction detected by late gadolinium enhancement on standard 2D inversion recovery sequences (2D LGE) underwent a CMR exam with 3D-SNIR on a 1.5T clinical CMR scanner (Aera, Siemens, Germany)... TI (= 250-300ms) was assessed with a 2D radial scout scan prior to 3D-SNIR... A total of about 12'000 radial readouts were acquired for each 3D scan during free breathing with 100% respiratory efficiency. 3D LGE datasets were compared to standard 2D LGE for scar tissue detection with Osirix® software... Scar tissue was segmented on reconstructed slices on standard 2D and 3D-SNIR LGE and multiplied by slice thickness... Thirteen patients (5 females, age 58±10y) were included... Time between 2D LGE and 3D LGE was 59 ± 64 days. 3D-SNIR successfully corrected for respiratory motion in all acquisitions... All scars visualized by 2D LGE could be identified by 3D-SNIR (example see figure 1)... Bland Altman-analyses and correlations showed a good agreement of quantification of scar volume obtained by 3D-SNIR compared to standard 2D LGE: -6.3±4.1ml, linear regression: r=0.977, p<0.001 (figure 2). 3D scar volume was 24.3±15ml vs. 2D 30.6±17ml, p<0.001... Intraobserver variability was 0.3±4.9ml, r=0.985, p<0.001; interobserver 1.5±9.9ml, r=0.74, p=0.014... Detection of myocardial scar by 3D-SNIR is feasible and shows a good agreement with standard 2D LGE... The mean difference of -6.3ml might be explained by the higher spatial resolution of the 3D sequence.

No MeSH data available.


Related in: MedlinePlus