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Measuring ventricular volumes during exercise with vertical long axis cines

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Imaging cardiac function during exercise remains difficult... La Gerche et al (Circ... Cardiovasc... Imaging 2013) may have solved this by linking the short axis images to the respiratory cycle with additional long axis imaging, but using a not widely available in-house software... VLA is perpendicular to the diaphragm, so the diaphragmatic motion and the breathing cycle can be followed... The VLA plane shows the atrioventricular border, hence reduces error... Imaging was carried out at rest (10 second/slice to include a full breathing cycle in each cine) and during two stages of exercise, at target heart rates of 150% and 180% of resting... All images were diagnostic regarding endocardium detection, atrioventricular valve position and breathing cycle detection (Image)... Standard volumes correlated well with real-time VLA volumes (LVEDV 169.73+-39.51ml vs 210.39+-40.36ml r=0.975 p< 0.0005, LVESV 68.13+-21.91ml vs 84.97+-16ml r=0.956 p<0.001, LVSV 101.6+-18.91ml vs 125.42+-26.97ml r=0.931, p<0.005)... Physiological response was observed: 1) Ejection fraction of both ventricles increased significantly from rest through moderate to higher level of exercise, either measured on inspiration or expiration (from 7 to 13 percentage points, p<0.05 in each cases). 2) Left ventricular stroke volume increased significantly from rest to moderate and from rest to high level of exercise on expiration, 125.42+-26.97ml vs 135.56+-23.35ml (p<0.005) and 141.71+-34.78 (p<0.02), respectively. 3) A difference between RV stroke volume on inspiration (RVSVinsp) and RV stroke volume on expiration (RVSVexp) became significant at peak exercise (RVSVinsp 136.24+-43.09ml vs RVSVexp 115.98ml+-34.62, p<0.02)... The latter two findings may show the effect of the respiratory pump on the circulation... Our pilot study shows that it is feasible measuring ventricular volumes during exercise, using a widely available sequence and without the need for additional customised software... Further work is being undertaken to confirm these results in a large scale population.

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Measuring ventricular volumes during exercise with vertical long axis cines
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4328864&req=5

View Article: PubMed Central - HTML

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Imaging cardiac function during exercise remains difficult... La Gerche et al (Circ... Cardiovasc... Imaging 2013) may have solved this by linking the short axis images to the respiratory cycle with additional long axis imaging, but using a not widely available in-house software... VLA is perpendicular to the diaphragm, so the diaphragmatic motion and the breathing cycle can be followed... The VLA plane shows the atrioventricular border, hence reduces error... Imaging was carried out at rest (10 second/slice to include a full breathing cycle in each cine) and during two stages of exercise, at target heart rates of 150% and 180% of resting... All images were diagnostic regarding endocardium detection, atrioventricular valve position and breathing cycle detection (Image)... Standard volumes correlated well with real-time VLA volumes (LVEDV 169.73+-39.51ml vs 210.39+-40.36ml r=0.975 p< 0.0005, LVESV 68.13+-21.91ml vs 84.97+-16ml r=0.956 p<0.001, LVSV 101.6+-18.91ml vs 125.42+-26.97ml r=0.931, p<0.005)... Physiological response was observed: 1) Ejection fraction of both ventricles increased significantly from rest through moderate to higher level of exercise, either measured on inspiration or expiration (from 7 to 13 percentage points, p<0.05 in each cases). 2) Left ventricular stroke volume increased significantly from rest to moderate and from rest to high level of exercise on expiration, 125.42+-26.97ml vs 135.56+-23.35ml (p<0.005) and 141.71+-34.78 (p<0.02), respectively. 3) A difference between RV stroke volume on inspiration (RVSVinsp) and RV stroke volume on expiration (RVSVexp) became significant at peak exercise (RVSVinsp 136.24+-43.09ml vs RVSVexp 115.98ml+-34.62, p<0.02)... The latter two findings may show the effect of the respiratory pump on the circulation... Our pilot study shows that it is feasible measuring ventricular volumes during exercise, using a widely available sequence and without the need for additional customised software... Further work is being undertaken to confirm these results in a large scale population.

No MeSH data available.