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Multiple painful brownish plaques associated with local hyperhidrosis.

Duman N, Erkin G, Atakan N, Gököz Ö - Dermatol Pract Concept (2015)

Bottom Line: Eccrine angiomatous hamartoma is a rare hamartomatous lesion characterized by proliferation of eccrine glands and small blood vessels, and occasionally other elements.It generally arises congenitally or later in childhood, as solitary or multiple lesions on the distal extremities.Adult-onset multiple lesions are very rare.

View Article: PubMed Central - PubMed

Affiliation: Afyon Kocatepe University, School of Medicine, Department of Dermatology, Afyonkarahisar, Turkey.

ABSTRACT
Eccrine angiomatous hamartoma is a rare hamartomatous lesion characterized by proliferation of eccrine glands and small blood vessels, and occasionally other elements. It generally arises congenitally or later in childhood, as solitary or multiple lesions on the distal extremities. Adult-onset multiple lesions are very rare. Herein we describe a 33-year-old male with symptomatic multiple eccrine angiomatous hamartoma lesions.

No MeSH data available.


Related in: MedlinePlus

Proliferative lobules with mucinous stroma in the deep dermis and subcutaneous tissue (H&E, ×10 original magnification). (Copyright: ©2015 Duman et al.)
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f2-dp0501a17: Proliferative lobules with mucinous stroma in the deep dermis and subcutaneous tissue (H&E, ×10 original magnification). (Copyright: ©2015 Duman et al.)

Mentions: To perform this test the plaque on the patient’s right leg was painted with iodine solution and allowed to dry thoroughly. Then, a starch powder was sprinkled on the surface and the appearance of purple-black speckling was observed, indicating presence of hyperhidrosis. Next, an incisional biopsy specimen was obtained from the same lesion. Hematoxylineosin (H&E) staining of the biopsy specimen showed lobules with mucinous stroma in the deep dermis and subcutaneous tissue (Figure 2). The lobules were composed of hyperplastic and proliferated eccrine glands, and numerous small blood vessels (Figure 3). With the clinical and histopathological findings, a diagnosis of eccrine angiomatous hamartoma (EAH) was made.


Multiple painful brownish plaques associated with local hyperhidrosis.

Duman N, Erkin G, Atakan N, Gököz Ö - Dermatol Pract Concept (2015)

Proliferative lobules with mucinous stroma in the deep dermis and subcutaneous tissue (H&E, ×10 original magnification). (Copyright: ©2015 Duman et al.)
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4325700&req=5

f2-dp0501a17: Proliferative lobules with mucinous stroma in the deep dermis and subcutaneous tissue (H&E, ×10 original magnification). (Copyright: ©2015 Duman et al.)
Mentions: To perform this test the plaque on the patient’s right leg was painted with iodine solution and allowed to dry thoroughly. Then, a starch powder was sprinkled on the surface and the appearance of purple-black speckling was observed, indicating presence of hyperhidrosis. Next, an incisional biopsy specimen was obtained from the same lesion. Hematoxylineosin (H&E) staining of the biopsy specimen showed lobules with mucinous stroma in the deep dermis and subcutaneous tissue (Figure 2). The lobules were composed of hyperplastic and proliferated eccrine glands, and numerous small blood vessels (Figure 3). With the clinical and histopathological findings, a diagnosis of eccrine angiomatous hamartoma (EAH) was made.

Bottom Line: Eccrine angiomatous hamartoma is a rare hamartomatous lesion characterized by proliferation of eccrine glands and small blood vessels, and occasionally other elements.It generally arises congenitally or later in childhood, as solitary or multiple lesions on the distal extremities.Adult-onset multiple lesions are very rare.

View Article: PubMed Central - PubMed

Affiliation: Afyon Kocatepe University, School of Medicine, Department of Dermatology, Afyonkarahisar, Turkey.

ABSTRACT
Eccrine angiomatous hamartoma is a rare hamartomatous lesion characterized by proliferation of eccrine glands and small blood vessels, and occasionally other elements. It generally arises congenitally or later in childhood, as solitary or multiple lesions on the distal extremities. Adult-onset multiple lesions are very rare. Herein we describe a 33-year-old male with symptomatic multiple eccrine angiomatous hamartoma lesions.

No MeSH data available.


Related in: MedlinePlus