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Incidental Merkel cell carcinoma in a cutaneous horn: a case report.

Schick BA, Tobe JS, Joseph MG, Rouse TB, Gabril MY - Dermatol Pract Concept (2015)

Bottom Line: Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy, which usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin.We present a 93-year-old female who presented with a "cutaneous horn" on the face.This case report highlights the significant association between MCC and squamous cell carcinoma and the uncommon clinical presentation of this combined tumor in the form of a cutaneous horn.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, London Health Sciences Centre and Western University, London, Ontario, Canada.

ABSTRACT
Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy, which usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin. We present a 93-year-old female who presented with a "cutaneous horn" on the face. On excision, histologic examination revealed a combined squamous cell carcinoma in situ with underlying MCC. Merkel cell polyomavirus immunohistochemistry was negative in this lesion. This case report highlights the significant association between MCC and squamous cell carcinoma and the uncommon clinical presentation of this combined tumor in the form of a cutaneous horn.

No MeSH data available.


Related in: MedlinePlus

The MCC cells demonstrate dot-like positivity for CK20. (Copyright: ©2015 Schick et al.)
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f3B-dp0501a08: The MCC cells demonstrate dot-like positivity for CK20. (Copyright: ©2015 Schick et al.)


Incidental Merkel cell carcinoma in a cutaneous horn: a case report.

Schick BA, Tobe JS, Joseph MG, Rouse TB, Gabril MY - Dermatol Pract Concept (2015)

The MCC cells demonstrate dot-like positivity for CK20. (Copyright: ©2015 Schick et al.)
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4325691&req=5

f3B-dp0501a08: The MCC cells demonstrate dot-like positivity for CK20. (Copyright: ©2015 Schick et al.)
Bottom Line: Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy, which usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin.We present a 93-year-old female who presented with a "cutaneous horn" on the face.This case report highlights the significant association between MCC and squamous cell carcinoma and the uncommon clinical presentation of this combined tumor in the form of a cutaneous horn.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, London Health Sciences Centre and Western University, London, Ontario, Canada.

ABSTRACT
Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine malignancy, which usually presents as an asymptomatic, rapidly growing, firm nodule on sun-damaged skin. We present a 93-year-old female who presented with a "cutaneous horn" on the face. On excision, histologic examination revealed a combined squamous cell carcinoma in situ with underlying MCC. Merkel cell polyomavirus immunohistochemistry was negative in this lesion. This case report highlights the significant association between MCC and squamous cell carcinoma and the uncommon clinical presentation of this combined tumor in the form of a cutaneous horn.

No MeSH data available.


Related in: MedlinePlus