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Microcystic adnexal carcinoma of the cheek-a case report with dermatoscopy and dermatopathology.

Inskip M, Magee J - Dermatol Pract Concept (2015)

Bottom Line: We present a case report of a microcystic adnexal carcinoma on the cheek of a 67-year-old man.Clinical, dermatoscopic and dermatopathologic images are presented.A search of the literature has not discovered any previously published dermatoscopy images of microcystic adenexal carcinoma.

View Article: PubMed Central - PubMed

Affiliation: Sun Patrol Skin Care Cancer Clinic, Berwick, Australia.

ABSTRACT
We present a case report of a microcystic adnexal carcinoma on the cheek of a 67-year-old man. Clinical, dermatoscopic and dermatopathologic images are presented. A search of the literature has not discovered any previously published dermatoscopy images of microcystic adenexal carcinoma.

No MeSH data available.


Related in: MedlinePlus

CEA stain marks some of the ductular lumina within the aggregates. This is a marker of eccrine and apocrine ducts, which would favor microcystic adnexal carcinoma. (Copyright: ©2014 Inskip, Magee.)
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f11-dp0501a07: CEA stain marks some of the ductular lumina within the aggregates. This is a marker of eccrine and apocrine ducts, which would favor microcystic adnexal carcinoma. (Copyright: ©2014 Inskip, Magee.)

Mentions: The differential diagnosis was between a microcystic adnexal carcinoma and a fibrosing basal cell carcinoma with follicular differentiation. Immunohistochemical stains were performed. The lesion stained positively for Ber-EP4. There was also strong CK15 positivity. CEA stained some lumina within the lesion. This staining pattern, although not entirely specific, was more in favour of microcystic adnexal carcinoma than fibrosing basal cell carcinoma. Ber-EP4 expression has been noted in 38% of microcystic adnexal carcinomas and 100% of basal cell carcinomas. However CK15 is expressed in 92% of microcystic adnexal carcinomas, whereas basal cell carcinomas are negative [6]. Hence, in conjunction with the positive CEA, the findings favoured a microcystic adnexal carcinoma (Figures 3 to 11).


Microcystic adnexal carcinoma of the cheek-a case report with dermatoscopy and dermatopathology.

Inskip M, Magee J - Dermatol Pract Concept (2015)

CEA stain marks some of the ductular lumina within the aggregates. This is a marker of eccrine and apocrine ducts, which would favor microcystic adnexal carcinoma. (Copyright: ©2014 Inskip, Magee.)
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4325690&req=5

f11-dp0501a07: CEA stain marks some of the ductular lumina within the aggregates. This is a marker of eccrine and apocrine ducts, which would favor microcystic adnexal carcinoma. (Copyright: ©2014 Inskip, Magee.)
Mentions: The differential diagnosis was between a microcystic adnexal carcinoma and a fibrosing basal cell carcinoma with follicular differentiation. Immunohistochemical stains were performed. The lesion stained positively for Ber-EP4. There was also strong CK15 positivity. CEA stained some lumina within the lesion. This staining pattern, although not entirely specific, was more in favour of microcystic adnexal carcinoma than fibrosing basal cell carcinoma. Ber-EP4 expression has been noted in 38% of microcystic adnexal carcinomas and 100% of basal cell carcinomas. However CK15 is expressed in 92% of microcystic adnexal carcinomas, whereas basal cell carcinomas are negative [6]. Hence, in conjunction with the positive CEA, the findings favoured a microcystic adnexal carcinoma (Figures 3 to 11).

Bottom Line: We present a case report of a microcystic adnexal carcinoma on the cheek of a 67-year-old man.Clinical, dermatoscopic and dermatopathologic images are presented.A search of the literature has not discovered any previously published dermatoscopy images of microcystic adenexal carcinoma.

View Article: PubMed Central - PubMed

Affiliation: Sun Patrol Skin Care Cancer Clinic, Berwick, Australia.

ABSTRACT
We present a case report of a microcystic adnexal carcinoma on the cheek of a 67-year-old man. Clinical, dermatoscopic and dermatopathologic images are presented. A search of the literature has not discovered any previously published dermatoscopy images of microcystic adenexal carcinoma.

No MeSH data available.


Related in: MedlinePlus