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Granuloma annulare and necrobiosis lipoidica with sequential occurrence in a patient: report and review of literature.

Rupley KA, Riahi RR, Hooper DO - Dermatol Pract Concept (2015)

Bottom Line: GA and NL are characterized histologically by areas of necrobiosis of collagen.We report on a 67-year-old Caucasian woman with a history of NL on the anterior shins that later developed lesions of GA on the breasts, trunk, and wrist.We also review the literature and discuss the characteristics of patients with concomitant GA and NL.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Louisiana State University, Baton Rouge, Louisiana, USA.

ABSTRACT
Granuloma annulare (GA) and necrobiosis lipoidica (NL) are granulomatous diseases of undetermined etiology. Rarely, both dermatoses have been reported to occur concomitantly in patients. GA and NL are characterized histologically by areas of necrobiosis of collagen. The two diseases share some common characteristics, which may suggest that these dermatoses could occur as a spectrum in some patients or possibly share a similar pathogenesis. We report on a 67-year-old Caucasian woman with a history of NL on the anterior shins that later developed lesions of GA on the breasts, trunk, and wrist. We also review the literature and discuss the characteristics of patients with concomitant GA and NL.

No MeSH data available.


Related in: MedlinePlus

Lower legs with irregular, annular plaques with erythematous rim and yellow, atrophic centers. (Copyright: ©2015 Rupley et al.)
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Related In: Results  -  Collection


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f1-dp0501a03: Lower legs with irregular, annular plaques with erythematous rim and yellow, atrophic centers. (Copyright: ©2015 Rupley et al.)

Mentions: Physical examination demonstrated erythematous annular plaques with an erythematous rim and atrophic center with yellow discoloration over the lower extremities bilaterally (Figure 1). The patient was treated with intralesional Kenalog with significant improvement.


Granuloma annulare and necrobiosis lipoidica with sequential occurrence in a patient: report and review of literature.

Rupley KA, Riahi RR, Hooper DO - Dermatol Pract Concept (2015)

Lower legs with irregular, annular plaques with erythematous rim and yellow, atrophic centers. (Copyright: ©2015 Rupley et al.)
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4325686&req=5

f1-dp0501a03: Lower legs with irregular, annular plaques with erythematous rim and yellow, atrophic centers. (Copyright: ©2015 Rupley et al.)
Mentions: Physical examination demonstrated erythematous annular plaques with an erythematous rim and atrophic center with yellow discoloration over the lower extremities bilaterally (Figure 1). The patient was treated with intralesional Kenalog with significant improvement.

Bottom Line: GA and NL are characterized histologically by areas of necrobiosis of collagen.We report on a 67-year-old Caucasian woman with a history of NL on the anterior shins that later developed lesions of GA on the breasts, trunk, and wrist.We also review the literature and discuss the characteristics of patients with concomitant GA and NL.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Louisiana State University, Baton Rouge, Louisiana, USA.

ABSTRACT
Granuloma annulare (GA) and necrobiosis lipoidica (NL) are granulomatous diseases of undetermined etiology. Rarely, both dermatoses have been reported to occur concomitantly in patients. GA and NL are characterized histologically by areas of necrobiosis of collagen. The two diseases share some common characteristics, which may suggest that these dermatoses could occur as a spectrum in some patients or possibly share a similar pathogenesis. We report on a 67-year-old Caucasian woman with a history of NL on the anterior shins that later developed lesions of GA on the breasts, trunk, and wrist. We also review the literature and discuss the characteristics of patients with concomitant GA and NL.

No MeSH data available.


Related in: MedlinePlus