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A comparative analysis of endoscopic thyroidectomy versus conventional thyroidectomy in clinically lymph node negative thyroid cancer.

Cho MJ, Park KS, Cho MJ, Yoo YB, Yang JH - Ann Surg Treat Res (2015)

Bottom Line: We practiced comparative analysis for clinicopathologic characteristics, surgical outcomes including postoperative complications, and recurred cases during follow-up periods of each group.Meanwhile, in postoperative complications, there were no statistically significant differences.During short follow-up periods, no recurrence or mortality case was observed.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Konkuk University School of Medicine, Seoul, Korea.

ABSTRACT

Purpose: Differentiated thyroid cancer has a good prognosis and high incidence in young women. Since endoscopic techniques were first recorded in 1996, surgical indications of endoscopic thyroidectomy have broadened. Therefore, the aim of this study is to investigate the usefulness of endoscopic thyroidectomy in clinically lymph node negative (cN0) thyroid cancer patients, based on oncologic completeness and safety, considering cosmetic outcomes.

Methods: From July 2009 to June 2011, a total of 166 cases had undergone endoscopic thyroidectomy using the BABA (bilateral axillo-breast approach) method or conventional open thyroidectomy by one surgeon. Finally, excluding 72 patients, 94 patients with cN0 thyroid cancer were divided into two groups according to operative methods and analyzed to compare differences between the two methods retrospectively (endoscopic group, n = 49; conventional open group, n = 45).

Results: We practiced comparative analysis for clinicopathologic characteristics, surgical outcomes including postoperative complications, and recurred cases during follow-up periods of each group. The results showed there was a tendency for patients, young, women rather than men, and having small size of thyroid cancer, to prefer endoscopic surgery to open surgery. Meanwhile, in postoperative complications, there were no statistically significant differences. During short follow-up periods, no recurrence or mortality case was observed.

Conclusion: Endoscopic thyroidectomy is a feasible and safe method for the treatment of clinically lymph node negative (cN0) thyroid cancer.

No MeSH data available.


Related in: MedlinePlus

Flow chart of accrued patients. LN, lymph node.
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Figure 1: Flow chart of accrued patients. LN, lymph node.

Mentions: From July 2009 to June 2011, we performed analyses for a total of 166 patients undergoing thyroidectomy with or without central LN dissection whose thyroids were diagnosed as a malignancy by preoperative ultrasound (US)-guided fine needle aspiration and cytology (FNAC) or suspicious of malignancy by preoperative neck US, neck CT, PET-CT. Of those, 72 patients were excluded from this study; 46 patients were excluded with more than one clinically positive LN in preoperative evaluation, one with no preoperative evaluation for regional LNs, two less than 18 years old, and 23 diagnosed as benign neoplasm in postoperative pathology. Finally, 94 patients with thyroid cancer of clinically radiological node negative were adopted for analysis, classified under two groups. That is, we divided 94 patients into group A including 49 patients undergoing endoscopic surgery using BABA (bilateral axillo-breast approach) and group B including 45 patients undergoing conventional open thyroidectomy (Fig. 1) (endoscopic group, n = 49; open group, n = 45). In each group, all patients were analyzed for clinicopathologic characteristics, operative extents, operative time, postoperative complications, and the existence of recurrence during follow-up periods by various tests including off-T4 Tg levels. We applied 1 ng/mL as cutoff Tg level to suggest a postoperative recurrence.


A comparative analysis of endoscopic thyroidectomy versus conventional thyroidectomy in clinically lymph node negative thyroid cancer.

Cho MJ, Park KS, Cho MJ, Yoo YB, Yang JH - Ann Surg Treat Res (2015)

Flow chart of accrued patients. LN, lymph node.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4325647&req=5

Figure 1: Flow chart of accrued patients. LN, lymph node.
Mentions: From July 2009 to June 2011, we performed analyses for a total of 166 patients undergoing thyroidectomy with or without central LN dissection whose thyroids were diagnosed as a malignancy by preoperative ultrasound (US)-guided fine needle aspiration and cytology (FNAC) or suspicious of malignancy by preoperative neck US, neck CT, PET-CT. Of those, 72 patients were excluded from this study; 46 patients were excluded with more than one clinically positive LN in preoperative evaluation, one with no preoperative evaluation for regional LNs, two less than 18 years old, and 23 diagnosed as benign neoplasm in postoperative pathology. Finally, 94 patients with thyroid cancer of clinically radiological node negative were adopted for analysis, classified under two groups. That is, we divided 94 patients into group A including 49 patients undergoing endoscopic surgery using BABA (bilateral axillo-breast approach) and group B including 45 patients undergoing conventional open thyroidectomy (Fig. 1) (endoscopic group, n = 49; open group, n = 45). In each group, all patients were analyzed for clinicopathologic characteristics, operative extents, operative time, postoperative complications, and the existence of recurrence during follow-up periods by various tests including off-T4 Tg levels. We applied 1 ng/mL as cutoff Tg level to suggest a postoperative recurrence.

Bottom Line: We practiced comparative analysis for clinicopathologic characteristics, surgical outcomes including postoperative complications, and recurred cases during follow-up periods of each group.Meanwhile, in postoperative complications, there were no statistically significant differences.During short follow-up periods, no recurrence or mortality case was observed.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Konkuk University School of Medicine, Seoul, Korea.

ABSTRACT

Purpose: Differentiated thyroid cancer has a good prognosis and high incidence in young women. Since endoscopic techniques were first recorded in 1996, surgical indications of endoscopic thyroidectomy have broadened. Therefore, the aim of this study is to investigate the usefulness of endoscopic thyroidectomy in clinically lymph node negative (cN0) thyroid cancer patients, based on oncologic completeness and safety, considering cosmetic outcomes.

Methods: From July 2009 to June 2011, a total of 166 cases had undergone endoscopic thyroidectomy using the BABA (bilateral axillo-breast approach) method or conventional open thyroidectomy by one surgeon. Finally, excluding 72 patients, 94 patients with cN0 thyroid cancer were divided into two groups according to operative methods and analyzed to compare differences between the two methods retrospectively (endoscopic group, n = 49; conventional open group, n = 45).

Results: We practiced comparative analysis for clinicopathologic characteristics, surgical outcomes including postoperative complications, and recurred cases during follow-up periods of each group. The results showed there was a tendency for patients, young, women rather than men, and having small size of thyroid cancer, to prefer endoscopic surgery to open surgery. Meanwhile, in postoperative complications, there were no statistically significant differences. During short follow-up periods, no recurrence or mortality case was observed.

Conclusion: Endoscopic thyroidectomy is a feasible and safe method for the treatment of clinically lymph node negative (cN0) thyroid cancer.

No MeSH data available.


Related in: MedlinePlus