Limits...
Case characteristics, hyperacute treatment, and outcome information from the clinical research center for stroke-fifth division registry in South Korea.

Kim BJ, Park JM, Kang K, Lee SJ, Ko Y, Kim JG, Cha JK, Kim DH, Nah HW, Han MK, Park TH, Park SS, Lee KB, Lee J, Hong KS, Cho YJ, Lee BC, Yu KH, Oh MS, Kim DE, Ryu WS, Cho KH, Kim JT, Choi JC, Kim WJ, Shin DI, Yeo MJ, Sohn SI, Hong JH, Lee J, Lee JS, Yoon BW, Bae HJ - J Stroke (2015)

Bottom Line: The rate of symptomatic hemorrhagic transformation (HT) was 7%, and that of any HT was 27% among recanalization-treated cases.Early neurological deterioration occurred in 15% of cases and were associated with longer length of stay and poorer 3-month outcomes.The above findings will be compared with other Asian and US registry data in this article.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea.

ABSTRACT
Characteristics of stroke cases, acute stroke care, and outcomes after stroke differ according to geographical and cultural background. To provide epidemiological and clinical data on stroke care in South Korea, we analyzed a prospective multicenter clinical stroke registry, the Clinical Research Center for Stroke-Fifth Division (CRCS-5). Patients were 58% male with a mean age of 67.2±12.9 years and median National Institutes of Health Stroke Scale score of 3 [1-8] points. Over the 6 years of operation, temporal trends were documented including increasing utilization of recanalization treatment with shorter onset-to-arrival delay and decremental length of stay. Acute recanalization treatment was performed in 12.7% of cases with endovascular treatment utilized in 36%, but the proportion of endovascular recanalization varied across centers. Door-to-IV alteplase delay had a median of 45 [33-68] min. The rate of symptomatic hemorrhagic transformation (HT) was 7%, and that of any HT was 27% among recanalization-treated cases. Early neurological deterioration occurred in 15% of cases and were associated with longer length of stay and poorer 3-month outcomes. The proportion of mRS scores of 0-1 was 42% on discharge, 50% at 3 months, and 55% at 1 year after the index stroke. Recurrent stroke up to 1 year occurred in 4.5% of patients; the rate was higher among older individuals and those with neurologically severe deficits. The above findings will be compared with other Asian and US registry data in this article.

No MeSH data available.


Related in: MedlinePlus

Failure curves for recurrent stroke events (A) and composite outcomes (B) after the index stroke.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4325643&req=5

Figure 7: Failure curves for recurrent stroke events (A) and composite outcomes (B) after the index stroke.

Mentions: Among the 19,441 cases whose long-term outcomes were available, recurrent stroke occurred in 4.5%, vascular death in 3.0%, and composite events of recurrent stroke, myocardial infarction and vascular death in 6.8% within 365 days of the index stroke (Table 8). The median time between stroke onset and the first event was 34 [7-116] days for recurrent stroke, 78 [21-237] days for myocardial infarction, 8 [3-44] days for vascular death, and 18 [5-90] days for composite events. The median observation period was 365 [116-382] days. Overall, the rate of vascular events after stroke was higher in the early period after stroke but decreased thereafter, for both recurrent stroke and composite events (Figure. 7).


Case characteristics, hyperacute treatment, and outcome information from the clinical research center for stroke-fifth division registry in South Korea.

Kim BJ, Park JM, Kang K, Lee SJ, Ko Y, Kim JG, Cha JK, Kim DH, Nah HW, Han MK, Park TH, Park SS, Lee KB, Lee J, Hong KS, Cho YJ, Lee BC, Yu KH, Oh MS, Kim DE, Ryu WS, Cho KH, Kim JT, Choi JC, Kim WJ, Shin DI, Yeo MJ, Sohn SI, Hong JH, Lee J, Lee JS, Yoon BW, Bae HJ - J Stroke (2015)

Failure curves for recurrent stroke events (A) and composite outcomes (B) after the index stroke.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4325643&req=5

Figure 7: Failure curves for recurrent stroke events (A) and composite outcomes (B) after the index stroke.
Mentions: Among the 19,441 cases whose long-term outcomes were available, recurrent stroke occurred in 4.5%, vascular death in 3.0%, and composite events of recurrent stroke, myocardial infarction and vascular death in 6.8% within 365 days of the index stroke (Table 8). The median time between stroke onset and the first event was 34 [7-116] days for recurrent stroke, 78 [21-237] days for myocardial infarction, 8 [3-44] days for vascular death, and 18 [5-90] days for composite events. The median observation period was 365 [116-382] days. Overall, the rate of vascular events after stroke was higher in the early period after stroke but decreased thereafter, for both recurrent stroke and composite events (Figure. 7).

Bottom Line: The rate of symptomatic hemorrhagic transformation (HT) was 7%, and that of any HT was 27% among recanalization-treated cases.Early neurological deterioration occurred in 15% of cases and were associated with longer length of stay and poorer 3-month outcomes.The above findings will be compared with other Asian and US registry data in this article.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea.

ABSTRACT
Characteristics of stroke cases, acute stroke care, and outcomes after stroke differ according to geographical and cultural background. To provide epidemiological and clinical data on stroke care in South Korea, we analyzed a prospective multicenter clinical stroke registry, the Clinical Research Center for Stroke-Fifth Division (CRCS-5). Patients were 58% male with a mean age of 67.2±12.9 years and median National Institutes of Health Stroke Scale score of 3 [1-8] points. Over the 6 years of operation, temporal trends were documented including increasing utilization of recanalization treatment with shorter onset-to-arrival delay and decremental length of stay. Acute recanalization treatment was performed in 12.7% of cases with endovascular treatment utilized in 36%, but the proportion of endovascular recanalization varied across centers. Door-to-IV alteplase delay had a median of 45 [33-68] min. The rate of symptomatic hemorrhagic transformation (HT) was 7%, and that of any HT was 27% among recanalization-treated cases. Early neurological deterioration occurred in 15% of cases and were associated with longer length of stay and poorer 3-month outcomes. The proportion of mRS scores of 0-1 was 42% on discharge, 50% at 3 months, and 55% at 1 year after the index stroke. Recurrent stroke up to 1 year occurred in 4.5% of patients; the rate was higher among older individuals and those with neurologically severe deficits. The above findings will be compared with other Asian and US registry data in this article.

No MeSH data available.


Related in: MedlinePlus