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Tumour endoprosthetic reconstruction for primary aggressive and malignant bone tumours of the distal femur.

Rubio D, Serrano M, Wang E - Malays Orthop J (2013)

Bottom Line: Outcome measures included prosthetic survival, functional outcome and complications.Survival rates, failure modes and functional outcomes are comparable to other reported studies.Supracondylar humerus, K-wire fixation, day care procedure.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopedics, Philippine General Hospital, Manila, Philippines.

ABSTRACT

Unlabelled: At the Philippine General Hospital, tumour endoprostheses have become an option for reconstruction after limb saving surgery for primary bone tumors. We performed a retrospective review of patients with primary bone tumors of the distal femur who underwent tumor excision and reconstruction using tumor endoprostheses. Outcome measures included prosthetic survival, functional outcome and complications. Twenty-two patients were evaluated; 14 males and 8 females, with a mean age of 18 years and a mean follow-up of 56 months. The overall 2-year endoprosthetic survival rate was 86%. Mean MSTS was 23/30. There were a total of 6 revisions. Failure modes included 3 infections, 3 aseptic loosening, 4 structural failures, 2 soft tissue failures and 3 tumor progression. Our early results show that tumor endoprosthesis reconstruction is an acceptable option for patients with primary bone tumor of the distal femur. Survival rates, failure modes and functional outcomes are comparable to other reported studies.

Key words: Supracondylar humerus, K-wire fixation, day care procedure.

No MeSH data available.


Related in: MedlinePlus

: A. knee radiograph of a patient with osteosarcoma of the distal femur. B. MRI of the distal femur in the same patient C. 1st stagereconstruction – resection of tumor, application of kunstcher nail and cement spacer D. Second stage tumor endoprosthesisreconstruction.
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Figure 1: : A. knee radiograph of a patient with osteosarcoma of the distal femur. B. MRI of the distal femur in the same patient C. 1st stagereconstruction – resection of tumor, application of kunstcher nail and cement spacer D. Second stage tumor endoprosthesisreconstruction.

Mentions: A total of 22 patients were included and evaluated: 14 malesand 8 females. Ten patients underwent a single stageprocedure (tumor excision and endoprosthetic reconstructionin a single surgery). Twelve (12) patients underwent a 2-stage reconstruction, with the first stage being resection oftumor, application of a long intramedullary Kuntscher nailand a cement spacer around the nail (figure 1). Mean age was 18 years (9 to 65), and mean follow-up was 56 months(24 to 180 months). Diagnoses included 20 patients withclassic high grade osteosarcoma and 2 patients with GiantCell Tumor of bone. All osteosarcoma patients received atleast 3 cycles of neoadjuvant chemotherapy prior to tumorEPR followed by another 3 courses of postoperativechemotherapy. For those patients who underwent stagedEPR, chemotherapy had already been completed prior to thesecond reconstructive surgery.


Tumour endoprosthetic reconstruction for primary aggressive and malignant bone tumours of the distal femur.

Rubio D, Serrano M, Wang E - Malays Orthop J (2013)

: A. knee radiograph of a patient with osteosarcoma of the distal femur. B. MRI of the distal femur in the same patient C. 1st stagereconstruction – resection of tumor, application of kunstcher nail and cement spacer D. Second stage tumor endoprosthesisreconstruction.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4322133&req=5

Figure 1: : A. knee radiograph of a patient with osteosarcoma of the distal femur. B. MRI of the distal femur in the same patient C. 1st stagereconstruction – resection of tumor, application of kunstcher nail and cement spacer D. Second stage tumor endoprosthesisreconstruction.
Mentions: A total of 22 patients were included and evaluated: 14 malesand 8 females. Ten patients underwent a single stageprocedure (tumor excision and endoprosthetic reconstructionin a single surgery). Twelve (12) patients underwent a 2-stage reconstruction, with the first stage being resection oftumor, application of a long intramedullary Kuntscher nailand a cement spacer around the nail (figure 1). Mean age was 18 years (9 to 65), and mean follow-up was 56 months(24 to 180 months). Diagnoses included 20 patients withclassic high grade osteosarcoma and 2 patients with GiantCell Tumor of bone. All osteosarcoma patients received atleast 3 cycles of neoadjuvant chemotherapy prior to tumorEPR followed by another 3 courses of postoperativechemotherapy. For those patients who underwent stagedEPR, chemotherapy had already been completed prior to thesecond reconstructive surgery.

Bottom Line: Outcome measures included prosthetic survival, functional outcome and complications.Survival rates, failure modes and functional outcomes are comparable to other reported studies.Supracondylar humerus, K-wire fixation, day care procedure.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopedics, Philippine General Hospital, Manila, Philippines.

ABSTRACT

Unlabelled: At the Philippine General Hospital, tumour endoprostheses have become an option for reconstruction after limb saving surgery for primary bone tumors. We performed a retrospective review of patients with primary bone tumors of the distal femur who underwent tumor excision and reconstruction using tumor endoprostheses. Outcome measures included prosthetic survival, functional outcome and complications. Twenty-two patients were evaluated; 14 males and 8 females, with a mean age of 18 years and a mean follow-up of 56 months. The overall 2-year endoprosthetic survival rate was 86%. Mean MSTS was 23/30. There were a total of 6 revisions. Failure modes included 3 infections, 3 aseptic loosening, 4 structural failures, 2 soft tissue failures and 3 tumor progression. Our early results show that tumor endoprosthesis reconstruction is an acceptable option for patients with primary bone tumor of the distal femur. Survival rates, failure modes and functional outcomes are comparable to other reported studies.

Key words: Supracondylar humerus, K-wire fixation, day care procedure.

No MeSH data available.


Related in: MedlinePlus