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Puffing topography and nicotine intake of electronic cigarette users.

Behar RZ, Hua M, Talbot P - PLoS ONE (2015)

Bottom Line: All parameters except total puff count were significantly different for Blu versus V2 EC.EC puffing topography was variable among participants in the study, but often similar within an individual between brands or days.These data can contribute to the development of a standard protocol for laboratory testing of EC products.

View Article: PubMed Central - PubMed

Affiliation: Cell Molecular and Developmental Biology Graduate Program, University of California Riverside, Riverside, California, United States of America; Department of Cell Biology and Neuroscience, University of California Riverside, Riverside, California, United States of America.

ABSTRACT

Background: Prior electronic cigarette (EC) topography data are based on two video analyses with limited parameters. Alternate methods for measuring topography are needed to understand EC use and nicotine intake.

Objectives: This study evaluated EC topography with a CReSS Pocket device and quantified nicotine intake.

Methods: Validation tests on pressure drop, flow rate, and volume confirmed reliable performance of the CReSS Pocket device. Twenty participants used Blu Cigs and V2 Cigs for 10 minute intervals with a 10-15 minute break between brands. Brand order was reversed and repeated within 7 days Data were analyzed to determine puff duration, puff count, volume, flow rate, peak flow, and inter-puff interval. Nicotine intake was estimated from cartomizer fluid consumption and topography data.

Results: Nine patterns of EC use were identified. The average puff count and inter-puff interval were 32 puffs and 17.9 seconds. All participants, except one, took more than 20 puffs/10 minutes. The averages for puff duration (2.65 seconds/puff), volume/puff (51 ml/puff), total puff volume (1,579 ml), EC fluid consumption (79.6 mg), flow rate (20 ml/s), and peak flow rate (27 ml/s) were determined for 10-minute sessions. All parameters except total puff count were significantly different for Blu versus V2 EC. Total volume for Blu versus V2 was four-times higher than for conventional cigarettes. Average nicotine intake for Blu and V2 across both sessions was 1.2 ± 0.5 mg and 1.4 ± 0.7 mg, respectively, which is similar to conventional smokers.

Conclusions: EC puffing topography was variable among participants in the study, but often similar within an individual between brands or days. Puff duration, inter-puff interval, and puff volume varied from conventional cigarette standards. Data on total puff volume and nicotine intake are consistent with compensatory usage of EC. These data can contribute to the development of a standard protocol for laboratory testing of EC products.

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Frequency distribution of puff count for all users.Frequency distribution of total puff counts for all users broken down into different puff number intervals (N = 20).
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pone.0117222.g002: Frequency distribution of puff count for all users.Frequency distribution of total puff counts for all users broken down into different puff number intervals (N = 20).

Mentions: The total number of puffs/10 minutes ranged from 13 to 42. As shown in the frequency graph (Fig. 2), most users took between 20–39 puffs/10 minutes, while fewer users took 40–43 puffs, and only one user took between 10–19 puffs.


Puffing topography and nicotine intake of electronic cigarette users.

Behar RZ, Hua M, Talbot P - PLoS ONE (2015)

Frequency distribution of puff count for all users.Frequency distribution of total puff counts for all users broken down into different puff number intervals (N = 20).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4321841&req=5

pone.0117222.g002: Frequency distribution of puff count for all users.Frequency distribution of total puff counts for all users broken down into different puff number intervals (N = 20).
Mentions: The total number of puffs/10 minutes ranged from 13 to 42. As shown in the frequency graph (Fig. 2), most users took between 20–39 puffs/10 minutes, while fewer users took 40–43 puffs, and only one user took between 10–19 puffs.

Bottom Line: All parameters except total puff count were significantly different for Blu versus V2 EC.EC puffing topography was variable among participants in the study, but often similar within an individual between brands or days.These data can contribute to the development of a standard protocol for laboratory testing of EC products.

View Article: PubMed Central - PubMed

Affiliation: Cell Molecular and Developmental Biology Graduate Program, University of California Riverside, Riverside, California, United States of America; Department of Cell Biology and Neuroscience, University of California Riverside, Riverside, California, United States of America.

ABSTRACT

Background: Prior electronic cigarette (EC) topography data are based on two video analyses with limited parameters. Alternate methods for measuring topography are needed to understand EC use and nicotine intake.

Objectives: This study evaluated EC topography with a CReSS Pocket device and quantified nicotine intake.

Methods: Validation tests on pressure drop, flow rate, and volume confirmed reliable performance of the CReSS Pocket device. Twenty participants used Blu Cigs and V2 Cigs for 10 minute intervals with a 10-15 minute break between brands. Brand order was reversed and repeated within 7 days Data were analyzed to determine puff duration, puff count, volume, flow rate, peak flow, and inter-puff interval. Nicotine intake was estimated from cartomizer fluid consumption and topography data.

Results: Nine patterns of EC use were identified. The average puff count and inter-puff interval were 32 puffs and 17.9 seconds. All participants, except one, took more than 20 puffs/10 minutes. The averages for puff duration (2.65 seconds/puff), volume/puff (51 ml/puff), total puff volume (1,579 ml), EC fluid consumption (79.6 mg), flow rate (20 ml/s), and peak flow rate (27 ml/s) were determined for 10-minute sessions. All parameters except total puff count were significantly different for Blu versus V2 EC. Total volume for Blu versus V2 was four-times higher than for conventional cigarettes. Average nicotine intake for Blu and V2 across both sessions was 1.2 ± 0.5 mg and 1.4 ± 0.7 mg, respectively, which is similar to conventional smokers.

Conclusions: EC puffing topography was variable among participants in the study, but often similar within an individual between brands or days. Puff duration, inter-puff interval, and puff volume varied from conventional cigarette standards. Data on total puff volume and nicotine intake are consistent with compensatory usage of EC. These data can contribute to the development of a standard protocol for laboratory testing of EC products.

Show MeSH