Haemonchotolerance in West African Dwarf goats: contribution to sustainable, anthelmintics-free helminth control in traditionally managed Nigerian dwarf goats.
Bottom Line: Here, we summarise the history of this breed and explain its economic importance in rural West Africa.If haemonchotolerance can be shown to be genetically controlled, it should be possible to exploit the underlying genes to improve GIN resistance among productive fibre and milk producing breeds of goats, most of which are highly susceptible to nematode infections.Either introgression of resistance alleles into susceptible breeds by conventional breeding, or transgenesis could be used to develop novel parasite-resistant, but highly productive breeds, or to improve the resistance of existing breeds, benefitting the local West African rural economy as well as global caprine livestock agriculture.
Affiliation: Faculty of Veterinary Medicine, University of Nigeria, Nsukka, Nigeria.Show MeSH
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Mentions: Correlations between total worm burden at necropsy and mean faecal egg counts (rs = 0.563, n = 32, P = 0.001) of goats during challenge infection with H. contortus in the experiment described in Figure 8. The best-fit line was calculated by least squares methods and is given only to guide the eye.
Affiliation: Faculty of Veterinary Medicine, University of Nigeria, Nsukka, Nigeria.