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Alteration in regional tissue oxygenation of preterm infants during placement in the semi-upright seating position.

Petrova A, Mehta R - Sci Rep (2015)

Bottom Line: Decrease in rSO2-C and rSO2-R (more than 1SD below baseline mean) was recorded in 26.7% and 6.6% of infants respectively, which persisted even after adjustment for variation in heart and respiratory rate, and pulse oximeter measured oxygen saturation (P, 0.0001).Re-positioning the infants from the car seat to supine position was associated with normalization of the rSO2-C.We concluded that approximately one-third of preterm infants show minor reduction of cerebral tissue oxygenation in the semi-upright (car seat) position.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901.

ABSTRACT
We investigated whether the cerebral (rSO2-C %) and renal (rSO2-R %) tissue oxygenation of preterm infants is altered by repositioning from the supine to semi-upright position for pre-discharge car seat testing. Near-infrared spectroscopy was used to measure rSO2-C and rSO2-R, which were recorded simultaneously with vital signs in 15 preterm infants for 30 minutes in supine, 60 minutes in the semi-upright (at 45 degrees in a car seat), and 30 minutes in the post-semi-upright (supine) position. Changes in rSO2-C and SO2-R were mostly within 1 Standard Deviation (SD) of baseline mean levels in the supine position. Decrease in rSO2-C and rSO2-R (more than 1SD below baseline mean) was recorded in 26.7% and 6.6% of infants respectively, which persisted even after adjustment for variation in heart and respiratory rate, and pulse oximeter measured oxygen saturation (P, 0.0001). Re-positioning the infants from the car seat to supine position was associated with normalization of the rSO2-C. Alteration in rSO2-C and rSO2-R in a car seat was independent from the gestational and post-conception age, weight and presence of anemia. We concluded that approximately one-third of preterm infants show minor reduction of cerebral tissue oxygenation in the semi-upright (car seat) position.

No MeSH data available.


Related in: MedlinePlus

Distribution of SDs of rSO2-C in the semi-upright position compared to the mean of rSO2-C in the supine position for each participant.
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f1: Distribution of SDs of rSO2-C in the semi-upright position compared to the mean of rSO2-C in the supine position for each participant.

Mentions: Individual analysis showed that in 60% of infants, changes in rSO2-C (%) and rSO2-R (%) in the semi-upright position were within +/−1SD of baseline mean, and 26.7% and 6.6% of infants respectively, had rSO2-C (%) and rSO2-R (%) levels more than 1SD below the mean in baseline supine position (Figure 1 and Figure 2). Concordant decrease in rSO2-C (%) and rSO2-R (%) levels of more than 1SD was recorded in one infant, who was born vaginally at 36 weeks with birth weight of 2075 grams, was not intubated, did not show evidence of anemia of prematurity, and was diagnosed with hyperbilirubinemia. Variation within +/−1SD of the baseline mean of rSO2-C (%) and rSO2-R (%) was seen in 86.7% and 66.7% of the infants respectively in the post semi-upright (supine) position. In one infant, the rSO2-C (%) and rSO2-R (%) were more than 1SD below the mean in the post semi-upright (supine) position. Significant changes in cerebral and renal tissue oxygenation seen in the semi-upright position were not associated with lower gestational age, post-conception age, weight at discharge, or presence of anemia (Table 3). Anemia was recorded in 25% of infants with rSO2-C levels more than 1SD below the baseline mean in the semi-upright position as compared to 55.0% of infants with rSO2-C changes that were less than 1SD below baseline mean.


Alteration in regional tissue oxygenation of preterm infants during placement in the semi-upright seating position.

Petrova A, Mehta R - Sci Rep (2015)

Distribution of SDs of rSO2-C in the semi-upright position compared to the mean of rSO2-C in the supine position for each participant.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4321184&req=5

f1: Distribution of SDs of rSO2-C in the semi-upright position compared to the mean of rSO2-C in the supine position for each participant.
Mentions: Individual analysis showed that in 60% of infants, changes in rSO2-C (%) and rSO2-R (%) in the semi-upright position were within +/−1SD of baseline mean, and 26.7% and 6.6% of infants respectively, had rSO2-C (%) and rSO2-R (%) levels more than 1SD below the mean in baseline supine position (Figure 1 and Figure 2). Concordant decrease in rSO2-C (%) and rSO2-R (%) levels of more than 1SD was recorded in one infant, who was born vaginally at 36 weeks with birth weight of 2075 grams, was not intubated, did not show evidence of anemia of prematurity, and was diagnosed with hyperbilirubinemia. Variation within +/−1SD of the baseline mean of rSO2-C (%) and rSO2-R (%) was seen in 86.7% and 66.7% of the infants respectively in the post semi-upright (supine) position. In one infant, the rSO2-C (%) and rSO2-R (%) were more than 1SD below the mean in the post semi-upright (supine) position. Significant changes in cerebral and renal tissue oxygenation seen in the semi-upright position were not associated with lower gestational age, post-conception age, weight at discharge, or presence of anemia (Table 3). Anemia was recorded in 25% of infants with rSO2-C levels more than 1SD below the baseline mean in the semi-upright position as compared to 55.0% of infants with rSO2-C changes that were less than 1SD below baseline mean.

Bottom Line: Decrease in rSO2-C and rSO2-R (more than 1SD below baseline mean) was recorded in 26.7% and 6.6% of infants respectively, which persisted even after adjustment for variation in heart and respiratory rate, and pulse oximeter measured oxygen saturation (P, 0.0001).Re-positioning the infants from the car seat to supine position was associated with normalization of the rSO2-C.We concluded that approximately one-third of preterm infants show minor reduction of cerebral tissue oxygenation in the semi-upright (car seat) position.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901.

ABSTRACT
We investigated whether the cerebral (rSO2-C %) and renal (rSO2-R %) tissue oxygenation of preterm infants is altered by repositioning from the supine to semi-upright position for pre-discharge car seat testing. Near-infrared spectroscopy was used to measure rSO2-C and rSO2-R, which were recorded simultaneously with vital signs in 15 preterm infants for 30 minutes in supine, 60 minutes in the semi-upright (at 45 degrees in a car seat), and 30 minutes in the post-semi-upright (supine) position. Changes in rSO2-C and SO2-R were mostly within 1 Standard Deviation (SD) of baseline mean levels in the supine position. Decrease in rSO2-C and rSO2-R (more than 1SD below baseline mean) was recorded in 26.7% and 6.6% of infants respectively, which persisted even after adjustment for variation in heart and respiratory rate, and pulse oximeter measured oxygen saturation (P, 0.0001). Re-positioning the infants from the car seat to supine position was associated with normalization of the rSO2-C. Alteration in rSO2-C and rSO2-R in a car seat was independent from the gestational and post-conception age, weight and presence of anemia. We concluded that approximately one-third of preterm infants show minor reduction of cerebral tissue oxygenation in the semi-upright (car seat) position.

No MeSH data available.


Related in: MedlinePlus