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Long term follow up of breast cancer patients treated with acupuncture for hot flashes.

Hervik J, Mjåland O - Springerplus (2014)

Bottom Line: The control group receiving sham (minimal acupuncture) demonstrated a HF reduction only at night during treatment, however the effect did not remain significant during the following 12 weeks.A mixed models procedure with diagonal covariance matrix was used for statistical analyses.However scores at the end of treatment and after 3 months showed a statistically significant difference between the groups, this difference lost its significance when scores were analyzed after 2 years.

View Article: PubMed Central - PubMed

Affiliation: Pain Clinic, Vestfold Hospital, Tønsberg, Norway.

ABSTRACT

Objective: Short term effects of acupuncture treatment for hot flashes (HF) in breast cancer patients have been demonstrated in several studies, including a randomized controlled trial, by the present authors. Results for the first 59 Tamoxifen medicated women receiving a 10 week course of acupuncture treatment have already been published. A significant reduction in the number of hot flashes was demonstrated both day and night, for up to three months following treatment in the women receiving traditional Chinese acupuncture. The control group receiving sham (minimal acupuncture) demonstrated a HF reduction only at night during treatment, however the effect did not remain significant during the following 12 weeks. The study was continued in order to investigate longer term effects of acupuncture treatment, and patient's quality of life two years after treatment.

Methods and materials: Eighty patients, who had 2 years previously been randomized to either a course of 15 acupuncture treatments or sham acupuncture (control) over a period of 10 weeks, were asked to fill out a Kupperman index (KI) indicating health related quality of life.

Results: Sixty one women returned KI questionnaires. A mixed models procedure with diagonal covariance matrix was used for statistical analyses. Baseline values between the sham-group and acupuncture group were not significantly different. However scores at the end of treatment and after 3 months showed a statistically significant difference between the groups, this difference lost its significance when scores were analyzed after 2 years.

Conclusion: Acupuncture seems to have a positive effect on health related quality of life for up three months post-treatment, this study suggests that these effects may be longer-term, however there was no significant effect 2 years later.

No MeSH data available.


Related in: MedlinePlus

Shows differences in KI scores between the two groups from baseline, through treatment, up until 2 years post treatment.
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Fig1: Shows differences in KI scores between the two groups from baseline, through treatment, up until 2 years post treatment.

Mentions: Group 2 – Sham/control (Figure 1).Figure 1


Long term follow up of breast cancer patients treated with acupuncture for hot flashes.

Hervik J, Mjåland O - Springerplus (2014)

Shows differences in KI scores between the two groups from baseline, through treatment, up until 2 years post treatment.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4320138&req=5

Fig1: Shows differences in KI scores between the two groups from baseline, through treatment, up until 2 years post treatment.
Mentions: Group 2 – Sham/control (Figure 1).Figure 1

Bottom Line: The control group receiving sham (minimal acupuncture) demonstrated a HF reduction only at night during treatment, however the effect did not remain significant during the following 12 weeks.A mixed models procedure with diagonal covariance matrix was used for statistical analyses.However scores at the end of treatment and after 3 months showed a statistically significant difference between the groups, this difference lost its significance when scores were analyzed after 2 years.

View Article: PubMed Central - PubMed

Affiliation: Pain Clinic, Vestfold Hospital, Tønsberg, Norway.

ABSTRACT

Objective: Short term effects of acupuncture treatment for hot flashes (HF) in breast cancer patients have been demonstrated in several studies, including a randomized controlled trial, by the present authors. Results for the first 59 Tamoxifen medicated women receiving a 10 week course of acupuncture treatment have already been published. A significant reduction in the number of hot flashes was demonstrated both day and night, for up to three months following treatment in the women receiving traditional Chinese acupuncture. The control group receiving sham (minimal acupuncture) demonstrated a HF reduction only at night during treatment, however the effect did not remain significant during the following 12 weeks. The study was continued in order to investigate longer term effects of acupuncture treatment, and patient's quality of life two years after treatment.

Methods and materials: Eighty patients, who had 2 years previously been randomized to either a course of 15 acupuncture treatments or sham acupuncture (control) over a period of 10 weeks, were asked to fill out a Kupperman index (KI) indicating health related quality of life.

Results: Sixty one women returned KI questionnaires. A mixed models procedure with diagonal covariance matrix was used for statistical analyses. Baseline values between the sham-group and acupuncture group were not significantly different. However scores at the end of treatment and after 3 months showed a statistically significant difference between the groups, this difference lost its significance when scores were analyzed after 2 years.

Conclusion: Acupuncture seems to have a positive effect on health related quality of life for up three months post-treatment, this study suggests that these effects may be longer-term, however there was no significant effect 2 years later.

No MeSH data available.


Related in: MedlinePlus